Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378904285> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W4378904285 endingPage "39" @default.
- W4378904285 startingPage "34" @default.
- W4378904285 abstract "There is a great need for more efficient and more widely used preventive treatment of post-operative abdominal adhesions. Objective - to study the type of adhesions in the abdominal cavity after open operations in the experiment. Materials and methods. The study was conducted on 90 white outbred rats divided into three groups. We mechanically damaged the surface of the small bowel segment in all rats. The control group (group 1) included 30 rats not administered any drugs into the abdominal cavity after the small bowel segment damage. The comparison group (group 2) consisted of 30 rats, which were introduced one mL of mezogel. The study group comprised 30 rats, which were administered a 1 mL mixture of metronidazole, dextran, contrykal (in a ratio of 1:1:0.1, respectively) + O2 into the abdominal cavity; the wound of the latter was closed using a layered suture technique. On days 5, 10 and 21, the tissues taken from the suture site, peritoneum, damaged small bowel segment, liver, and omentum were analysed histologically. Results. On day 10 in groups 1 and 2, compared to day 5, the proportion of filmy adhesions decreased by 45.9% (p=0.004), but the proportion of dense adhesions increased by 64.7%. The comparative between-group analysis on day 5 in groups 1 and 2 revealed no difference in the proportion of filmy adhesions, whereas in group 3 the proportion of filmy adhesions was 4% higher and the proportion of dense adhesions was 16.5% lower. Planar adhesions predominated in all groups. Conclusions. There were more filmy adhesions seen on day 1, and the complete dense adhesion formation was observed by day 21. Planar adhesions predominated (54.5 60.0%). The area of postoperative sutures was involved in the adhesion formation. The adhesions in the sutures - peritoneum area as well as the omental adhesions were detected in all animals. Introduction of drugs, mezogel or a mixture of metronidazole, dextran, contrykal + O2, into the abdominal cavity contributed to the reduction of adhesions between the small bowel loops. The experiments with laboratory animals were provided in accordance with all bioethical norms and guidelines. No conflict of interests was declared by the author." @default.
- W4378904285 created "2023-06-01" @default.
- W4378904285 creator A5086388759 @default.
- W4378904285 date "2022-12-27" @default.
- W4378904285 modified "2023-09-27" @default.
- W4378904285 title "Types and Localization of Abdominal Adhesions after Open Operations (Experimental Study)" @default.
- W4378904285 doi "https://doi.org/10.15574/ps.2022.77.34" @default.
- W4378904285 hasPublicationYear "2022" @default.
- W4378904285 type Work @default.
- W4378904285 citedByCount "0" @default.
- W4378904285 crossrefType "journal-article" @default.
- W4378904285 hasAuthorship W4378904285A5086388759 @default.
- W4378904285 hasBestOaLocation W43789042851 @default.
- W4378904285 hasConcept C126322002 @default.
- W4378904285 hasConcept C141071460 @default.
- W4378904285 hasConcept C178790620 @default.
- W4378904285 hasConcept C185592680 @default.
- W4378904285 hasConcept C2776001837 @default.
- W4378904285 hasConcept C2777327002 @default.
- W4378904285 hasConcept C2778536324 @default.
- W4378904285 hasConcept C2778754067 @default.
- W4378904285 hasConcept C2780936613 @default.
- W4378904285 hasConcept C3018023364 @default.
- W4378904285 hasConcept C71924100 @default.
- W4378904285 hasConcept C84416704 @default.
- W4378904285 hasConceptScore W4378904285C126322002 @default.
- W4378904285 hasConceptScore W4378904285C141071460 @default.
- W4378904285 hasConceptScore W4378904285C178790620 @default.
- W4378904285 hasConceptScore W4378904285C185592680 @default.
- W4378904285 hasConceptScore W4378904285C2776001837 @default.
- W4378904285 hasConceptScore W4378904285C2777327002 @default.
- W4378904285 hasConceptScore W4378904285C2778536324 @default.
- W4378904285 hasConceptScore W4378904285C2778754067 @default.
- W4378904285 hasConceptScore W4378904285C2780936613 @default.
- W4378904285 hasConceptScore W4378904285C3018023364 @default.
- W4378904285 hasConceptScore W4378904285C71924100 @default.
- W4378904285 hasConceptScore W4378904285C84416704 @default.
- W4378904285 hasIssue "4(77)" @default.
- W4378904285 hasLocation W43789042851 @default.
- W4378904285 hasOpenAccess W4378904285 @default.
- W4378904285 hasPrimaryLocation W43789042851 @default.
- W4378904285 hasRelatedWork W2086321358 @default.
- W4378904285 hasRelatedWork W2146471587 @default.
- W4378904285 hasRelatedWork W2347352101 @default.
- W4378904285 hasRelatedWork W2366795316 @default.
- W4378904285 hasRelatedWork W2378978068 @default.
- W4378904285 hasRelatedWork W2421528425 @default.
- W4378904285 hasRelatedWork W3110115602 @default.
- W4378904285 hasRelatedWork W3201331352 @default.
- W4378904285 hasRelatedWork W4292510257 @default.
- W4378904285 hasRelatedWork W4378904285 @default.
- W4378904285 isParatext "false" @default.
- W4378904285 isRetracted "false" @default.
- W4378904285 workType "article" @default.