FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378909249> ?p ?o ?g. }

• W4378909249 endingPage "906" @default.
• W4378909249 startingPage "896" @default.
• W4378909249 abstract "Background: The etiology of ovarian cancer is not well-understood; numerous metabolomics profiling, epidemiological, and hospital-based case control studies have associated abnormal levels of blood glucose and serum lipids with the risk and the prognosis of various types of cancers including ovarian cancer. The association between the risk of the incidence of ovarian cancer and the alterations in the levels of blood glucose and serum lipids is not well defined. Objective: In this study we aimed to compare the levels of blood glucose, triacylglycerols, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol in patients with different stages of ovarian cancer and healthy controls to determine how they relate to the risk and prognosis of ovarian cancer. Methodology: In a case-control cross sectional study, we enrolled ninety-nine Sudanese women, diagnosed with ovarian cancer but had not received any kind of treatment as the study group, and a control group of forty-one age-matched, apparently healthy women. The patients were classified according to the International Federation of Obstetricians and Gynecologists staging system into two groups: early stages (stage I & II) and late stages (stages III & IV). Blood glucose and serum lipids; triacylglycerols, total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol were determined by enzymatic colorimetric methods using commercially available analytical kits. The IBM SPSS version 20 software was used for statistical analysis. A Mann-Whitney U test was used for comparison of the median concentrations of blood glucose, triacylglycerols, total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol in the study groups. Logistic regression model was used to estimate the relative risk of ovarian cancer in relation to levels of blood glucose and serum lipids. P value of 0.05 was considered significant. Results: Our data indicated significantly higher levels of blood glucose (p , triacylglycerols (p = 0.002), and low-density lipoprotein cholesterol (p , and lower levels of high-density lipoprotein cholesterol (p = 0.023), in ovarian cancer patients compared to the control subjects. No significant difference was found in the levels of blood glucose or any of the serum lipids between patients in the early stages (stage I & II) and those in late stages (stage III & IV) of ovarian cancer. The logistic regression analysis indicated significant association between the elevated levels of the blood glucose, triacylglycerols and low-density lipoprotein cholesterol and the risk of the ovarian cancer. Conclusion: We conclude that the levels of blood glucose, triacylglycerols, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol differ significantly between ovarian cancer patients and the healthy control subjects. The risk of ovarian cancer was positively associated with the levels of blood glucose, triacylglycerols and low-density lipoprotein cholesterol, and negatively associated with levels of high-density lipoprotein cholesterol. Therefore, determination of blood glucose and serum lipids, particularly, triacylglycerols, low-density lipoprotein cholesterol may be helpful as diagnostic indicators of ovarian cancer (OC)." @default.
• W4378909249 created "2023-06-01" @default.
• W4378909249 creator A5002789251 @default.
• W4378909249 creator A5031490281 @default.
• W4378909249 creator A5049206398 @default.
• W4378909249 creator A5060651757 @default.
• W4378909249 date "2023-01-01" @default.
• W4378909249 modified "2023-10-01" @default.
• W4378909249 title "Altered Levels of Blood Glucose and Serum Lipids in Sudanese Patients with Ovarian Cancer" @default.
• W4378909249 cites W1946263363 @default.
• W4378909249 cites W1975065707 @default.
• W4378909249 cites W1983401297 @default.
• W4378909249 cites W1990089345 @default.
• W4378909249 cites W1991455406 @default.
• W4378909249 cites W2001875378 @default.
• W4378909249 cites W2059010575 @default.
• W4378909249 cites W2060399785 @default.
• W4378909249 cites W2062552860 @default.
• W4378909249 cites W2069813771 @default.
• W4378909249 cites W2076790491 @default.
• W4378909249 cites W2116404316 @default.
• W4378909249 cites W2118313918 @default.
• W4378909249 cites W2122321408 @default.
• W4378909249 cites W2424671667 @default.
• W4378909249 cites W2516506539 @default.
• W4378909249 cites W2887171816 @default.
• W4378909249 cites W2910523209 @default.
• W4378909249 cites W2943415606 @default.
• W4378909249 cites W2971196963 @default.
• W4378909249 cites W3010765451 @default.
• W4378909249 cites W3032008135 @default.
• W4378909249 cites W3176057307 @default.
• W4378909249 cites W3193400153 @default.
• W4378909249 cites W3199080466 @default.
• W4378909249 cites W4225155319 @default.
• W4378909249 cites W4310086081 @default.
• W4378909249 cites W4321496222 @default.
• W4378909249 cites W2920832361 @default.
• W4378909249 doi "https://doi.org/10.4236/ojog.2023.135077" @default.
• W4378909249 hasPublicationYear "2023" @default.
• W4378909249 type Work @default.
• W4378909249 citedByCount "0" @default.
• W4378909249 crossrefType "journal-article" @default.
• W4378909249 hasAuthorship W4378909249A5002789251 @default.
• W4378909249 hasAuthorship W4378909249A5031490281 @default.
• W4378909249 hasAuthorship W4378909249A5049206398 @default.
• W4378909249 hasAuthorship W4378909249A5060651757 @default.
• W4378909249 hasBestOaLocation W43789092491 @default.
• W4378909249 hasConcept C120665830 @default.
• W4378909249 hasConcept C121332964 @default.
• W4378909249 hasConcept C121608353 @default.
• W4378909249 hasConcept C126322002 @default.
• W4378909249 hasConcept C134018914 @default.
• W4378909249 hasConcept C139572402 @default.
• W4378909249 hasConcept C143998085 @default.
• W4378909249 hasConcept C2778163477 @default.
• W4378909249 hasConcept C2780072125 @default.
• W4378909249 hasConcept C2780427987 @default.
• W4378909249 hasConcept C2780541478 @default.
• W4378909249 hasConcept C42407357 @default.
• W4378909249 hasConcept C61511704 @default.
• W4378909249 hasConcept C71924100 @default.
• W4378909249 hasConcept C90924648 @default.
• W4378909249 hasConceptScore W4378909249C120665830 @default.
• W4378909249 hasConceptScore W4378909249C121332964 @default.
• W4378909249 hasConceptScore W4378909249C121608353 @default.
• W4378909249 hasConceptScore W4378909249C126322002 @default.
• W4378909249 hasConceptScore W4378909249C134018914 @default.
• W4378909249 hasConceptScore W4378909249C139572402 @default.
• W4378909249 hasConceptScore W4378909249C143998085 @default.
• W4378909249 hasConceptScore W4378909249C2778163477 @default.
• W4378909249 hasConceptScore W4378909249C2780072125 @default.
• W4378909249 hasConceptScore W4378909249C2780427987 @default.
• W4378909249 hasConceptScore W4378909249C2780541478 @default.
• W4378909249 hasConceptScore W4378909249C42407357 @default.
• W4378909249 hasConceptScore W4378909249C61511704 @default.
• W4378909249 hasConceptScore W4378909249C71924100 @default.
• W4378909249 hasConceptScore W4378909249C90924648 @default.
• W4378909249 hasIssue "05" @default.
• W4378909249 hasLocation W43789092491 @default.
• W4378909249 hasOpenAccess W4378909249 @default.
• W4378909249 hasPrimaryLocation W43789092491 @default.
• W4378909249 hasRelatedWork W1976602105 @default.
• W4378909249 hasRelatedWork W2005998106 @default.
• W4378909249 hasRelatedWork W2044844051 @default.
• W4378909249 hasRelatedWork W2068768710 @default.
• W4378909249 hasRelatedWork W2108336629 @default.
• W4378909249 hasRelatedWork W2118738696 @default.
• W4378909249 hasRelatedWork W2157219243 @default.
• W4378909249 hasRelatedWork W2413861530 @default.
• W4378909249 hasRelatedWork W4233524856 @default.
• W4378909249 hasRelatedWork W4244653511 @default.
• W4378909249 hasVolume "13" @default.
• W4378909249 isParatext "false" @default.
• W4378909249 isRetracted "false" @default.
• W4378909249 workType "article" @default.