FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4378966180> ?p ?o ?g. }

• W4378966180 abstract "<div>Abstract<p>Since its inception two years ago, the international, multicenter Pancreatic Cancer Early Detection (PRECEDE) Consortium has enrolled high-risk individuals (HRI) undergoing pancreatic ductal adenocarcinoma (PDAC) surveillance. Herein we aim to evaluate enrollment disparities in PRECEDE. Data on HRIs enrolled between May 2020 and March 2022 were collected, with HRIs defined as participants enrolled in PRECEDE meeting guideline-based criteria for PDAC surveillance. Of 1,273 HRIs enrolled, 1,113 were eligible for inclusion, with 47.2% meeting familial pancreatic cancer criteria without a known pathogenic variant (PV) and the remainder having a pathogenic variant in a PDAC-risk gene (<i>CDKN2A</i>, <i>STK11</i>, <i>PRSS1</i>, <i>BRCA1</i>, <i>BRCA2</i>, <i>PALB2</i>, <i>ATM</i>, <i>MLH1</i>, <i>MSH2</i>, <i>MSH6</i>, <i>PMS2</i>, or <i>EPCAM</i>). Study participants were predominantly from the United States (82.7%), the most common age range at enrollment was 60–69 years (37.4%), and a non-PDAC cancer was present in 32.4%. There were racial/ethnic- and sex-based disparities among enrolled subjects, as the majority of participants were female (65.9%) and self-reported white (87.7%), with only 2.9% having Hispanic ethnicity. While more than 97% of participants consented to utilize imaging data and biosamples for research, there was no difference in rate of consent based on race/ethnicity, sex, or age, thereby demonstrating uniform participation in research activities among all subgroups after enrollment. Ensuring that diversity of HRIs in PDAC surveillance programs mirrors the communities served by participating centers is important. Substantial racial/ethnic- and sex-based disparities persist among recently enrolled HRIs undergoing PDAC surveillance, and therefore reducing these disparities will be a major focus of the PRECEDE Consortium moving forward.</p>Prevention Relevance:<p>Pancreatic cancer surveillance is critical to decreasing pancreatic cancer mortality; therefore, it is important that pancreatic cancer surveillance studies enroll diverse patients. We demonstrate that substantial racial/ethnic- and sex-based disparities exist amongst enrollment in the international PRECEDE consortium, highlighting the dire need for future efforts to reduce these disparities.</p><p><i><a href=https://aacrjournals.org/cancerpreventionresearch/article/doi/10.1158/1940-6207.CAPR-23-0086 target=_blank>See related Spotlight, p. 305</a></i></p></div>" @default.
• W4378966180 created "2023-06-02" @default.
• W4378966180 creator A5008464992 @default.
• W4378966180 creator A5014224572 @default.
• W4378966180 creator A5018088794 @default.
• W4378966180 creator A5027783591 @default.
• W4378966180 creator A5030459924 @default.
• W4378966180 creator A5030627781 @default.
• W4378966180 creator A5032367500 @default.
• W4378966180 creator A5033918369 @default.
• W4378966180 creator A5034549343 @default.
• W4378966180 creator A5034561048 @default.
• W4378966180 creator A5035166264 @default.
• W4378966180 creator A5037038521 @default.
• W4378966180 creator A5037680432 @default.
• W4378966180 creator A5038045975 @default.
• W4378966180 creator A5039387801 @default.
• W4378966180 creator A5040251918 @default.
• W4378966180 creator A5043802158 @default.
• W4378966180 creator A5044335909 @default.
• W4378966180 creator A5045078700 @default.
• W4378966180 creator A5046617764 @default.
• W4378966180 creator A5051071221 @default.
• W4378966180 creator A5056335013 @default.
• W4378966180 creator A5063747371 @default.
• W4378966180 creator A5063856973 @default.
• W4378966180 creator A5069230382 @default.
• W4378966180 creator A5069874443 @default.
• W4378966180 creator A5070083610 @default.
• W4378966180 creator A5071888326 @default.
• W4378966180 creator A5072140815 @default.
• W4378966180 creator A5072357635 @default.
• W4378966180 creator A5072361619 @default.
• W4378966180 creator A5086897381 @default.
• W4378966180 creator A5087885378 @default.
• W4378966180 creator A5089839809 @default.
• W4378966180 creator A5092063033 @default.
• W4378966180 date "2023-06-01" @default.
• W4378966180 modified "2023-09-25" @default.
• W4378966180 title "Data from Racial, Ethnic, and Sex-based Disparities among High-risk Individuals Undergoing Pancreatic Cancer Surveillance" @default.
• W4378966180 doi "https://doi.org/10.1158/1940-6207.c.6674718.v1" @default.
• W4378966180 hasPublicationYear "2023" @default.
• W4378966180 type Work @default.
• W4378966180 citedByCount "0" @default.
• W4378966180 crossrefType "posted-content" @default.
• W4378966180 hasAuthorship W4378966180A5008464992 @default.
• W4378966180 hasAuthorship W4378966180A5014224572 @default.
• W4378966180 hasAuthorship W4378966180A5018088794 @default.
• W4378966180 hasAuthorship W4378966180A5027783591 @default.
• W4378966180 hasAuthorship W4378966180A5030459924 @default.
• W4378966180 hasAuthorship W4378966180A5030627781 @default.
• W4378966180 hasAuthorship W4378966180A5032367500 @default.
• W4378966180 hasAuthorship W4378966180A5033918369 @default.
• W4378966180 hasAuthorship W4378966180A5034549343 @default.
• W4378966180 hasAuthorship W4378966180A5034561048 @default.
• W4378966180 hasAuthorship W4378966180A5035166264 @default.
• W4378966180 hasAuthorship W4378966180A5037038521 @default.
• W4378966180 hasAuthorship W4378966180A5037680432 @default.
• W4378966180 hasAuthorship W4378966180A5038045975 @default.
• W4378966180 hasAuthorship W4378966180A5039387801 @default.
• W4378966180 hasAuthorship W4378966180A5040251918 @default.
• W4378966180 hasAuthorship W4378966180A5043802158 @default.
• W4378966180 hasAuthorship W4378966180A5044335909 @default.
• W4378966180 hasAuthorship W4378966180A5045078700 @default.
• W4378966180 hasAuthorship W4378966180A5046617764 @default.
• W4378966180 hasAuthorship W4378966180A5051071221 @default.
• W4378966180 hasAuthorship W4378966180A5056335013 @default.
• W4378966180 hasAuthorship W4378966180A5063747371 @default.
• W4378966180 hasAuthorship W4378966180A5063856973 @default.
• W4378966180 hasAuthorship W4378966180A5069230382 @default.
• W4378966180 hasAuthorship W4378966180A5069874443 @default.
• W4378966180 hasAuthorship W4378966180A5070083610 @default.
• W4378966180 hasAuthorship W4378966180A5071888326 @default.
• W4378966180 hasAuthorship W4378966180A5072140815 @default.
• W4378966180 hasAuthorship W4378966180A5072357635 @default.
• W4378966180 hasAuthorship W4378966180A5072361619 @default.
• W4378966180 hasAuthorship W4378966180A5086897381 @default.
• W4378966180 hasAuthorship W4378966180A5087885378 @default.
• W4378966180 hasAuthorship W4378966180A5089839809 @default.
• W4378966180 hasAuthorship W4378966180A5092063033 @default.
• W4378966180 hasConcept C121608353 @default.
• W4378966180 hasConcept C126322002 @default.
• W4378966180 hasConcept C143998085 @default.
• W4378966180 hasConcept C2780210213 @default.
• W4378966180 hasConcept C71924100 @default.
• W4378966180 hasConceptScore W4378966180C121608353 @default.
• W4378966180 hasConceptScore W4378966180C126322002 @default.
• W4378966180 hasConceptScore W4378966180C143998085 @default.
• W4378966180 hasConceptScore W4378966180C2780210213 @default.
• W4378966180 hasConceptScore W4378966180C71924100 @default.
• W4378966180 hasLocation W43789661801 @default.
• W4378966180 hasOpenAccess W4378966180 @default.
• W4378966180 hasPrimaryLocation W43789661801 @default.
• W4378966180 hasRelatedWork W2007737033 @default.
• W4378966180 hasRelatedWork W2043890160 @default.
• W4378966180 hasRelatedWork W2122804063 @default.
• W4378966180 hasRelatedWork W2337729630 @default.
• W4378966180 hasRelatedWork W2365364931 @default.
• W4378966180 hasRelatedWork W2401514044 @default.
• W4378966180 hasRelatedWork W2418638721 @default.

• next