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- W4378974429 abstract "•This is the first report of a germline DICER1-associated Sertoli-Leydig cell tumor (SLCT) diagnosed in pregnancy.•SLCT is linked to DICER1 pathogenic variants, but little is known about management of DICER1-associated SLCT.•There is an extended risk for metachronous SLCT in patients with germline DICER1 pathogenic variants who retain an ovary.•Prophylactic contralateral salpingo-oophorectomy may be offered with shared decision making to patients with inherited SLCT.•Genetic testing for DICER1 should be offered to all patients with moderately or poorly differentiated SLCT." @default.
- W4378974429 created "2023-06-02" @default.
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- W4378974429 date "2023-08-01" @default.
- W4378974429 modified "2023-09-30" @default.
- W4378974429 title "Sertoli-Leydig cell tumor associated with a germline DICER1 pathogenic variant diagnosed during pregnancy: Considerations for treatment, surveillance, and prevention" @default.
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- W4378974429 doi "https://doi.org/10.1016/j.gore.2023.101215" @default.
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