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• W4378978503 abstract ": This study evaluated the impact of Fox Green (FG) against methylthioninium chloride (MTC)-facilitated photodynamic therapy (PDT) as an adjunctive to manual scaling (MS) on the peri-implant clinical and cytokine parameters in type-2 diabetes mellitus (DM) patients with peri-implantitis. : Patients were divided into group-A comprising 13 patients who received adjunctive FG-PDT using a diode laser (wavelength: 810 nm; irradiation power: 300 mW; irradiation time: 30 seconds; fluence: 56 Jcm−2), group-B comprising 12 patients who received adjunctive MTC-PDT using a diode laser (wavelength: 660 nm; irradiation power: 100 mW; irradiation time: 120 seconds/site; fluence: 30 Jcm−2), and group-C comprising 13 patients who received MS alone [control group]). After diagnosing the diabetics with peri-implantitis (established on eligibility criteria), a structured questionnaire was used to gather the information of the participants. Plaque (PS) and bleeding scores (BS), along with peri-implant probing scores (PPS) and peri-implant bone loss (PIBL), together with immunological variables (interleukin [IL]-6, tumor necrosis factor-alpha [TNF-α], and advanced glycation end products [AGEs]) were measured in all study group participants at baseline, 3-month, and 6-month follow-ups. : A significant reduction was observed for PS, BS, and PPS within all tested groups at each follow-up visits compared from their baseline values (p<0.05). However, a substantial decrease in PIBL was observed in all study group patients at 6-month follow-up as compared to 3-month follow-up (p<0.05). Regarding the levels of IL-6 and TNF-α, a substantial reduction was observed in all study groups until 6-month from their baseline scores (p<0.05). However, no changes were observed in the levels of AGEs in any group at either visit (p>0.05). : In DM patients with periimplantitis, adjunctive FG-PDT and MTC-PDT exhibited comparable outcomes in terms of peri-implant clinical as well as pro-inflammatory characteristics than MS alone among peri-implantitis patients with DM." @default.
• W4378978503 created "2023-06-02" @default.
• W4378978503 creator A5022480946 @default.
• W4378978503 date "2023-09-01" @default.
• W4378978503 modified "2023-09-27" @default.
• W4378978503 title "Effectiveness of two photosensitizer-mediated photodynamic therapy for treating moderate peri-implant infections in type-II diabetes mellitus patients: A randomized clinical trial" @default.
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• W4378978503 doi "https://doi.org/10.1016/j.pdpdt.2023.103643" @default.
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• W4378978503 hasPublicationYear "2023" @default.
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