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• W4379094599 abstract "Abstract Objective This study was undertaken to determine the short‐term and longer term impact of sociodemographic disadvantage on the emotional–behavioral status of youths with new onset epilepsy and their unaffected siblings at the time of diagnosis and the subsequent 3 years. Methods Three hundred twelve youths with newly diagnosed epilepsies and 223 unaffected siblings, aged 6–16 years, were independently assessed regarding their emotional and behavioral status by their parents and teachers at baseline, and at 18 at 36 months later; youths with seizures also completed self‐report measures of depression, anxiety, and hostility at those three time points. A sociodemographic disadvantage score was computed for each family (children with newly diagnosed seizures and their siblings), and families were separated into four categories from most disadvantaged to least disadvantaged. Results In both children and siblings, the least disadvantaged group exhibited the lowest level of neurobehavioral problems, whereas the most disadvantaged group showed a higher level of neurobehavioral problems across all the same behavior metrics. Findings remained stable and significant across all informants (parent, teacher, child) and across all time periods (throughout the 3‐year period). Furthermore, both corrected and uncorrected linear regression analyses indicated that disadvantage was a more constant and stable predictor of behavioral and emotional problems over time compared to clinical seizure characteristics and abnormalities in magnetic resonance imaging and electroencephalographic testing. Significance Sociodemographic disadvantage bears a strong relationship to youths with emotional and behavioral problems both at the time of diagnosis as well as prospectively. The relationship is robust and reflected in reports from multiple informants (parent, teacher, child self‐report), evident in siblings as well, and possibly more explanatory than traditional clinical seizure variables. Future studies will be needed to determine whether this disadvantage factor is modifiable with early intervention." @default.
• W4379094599 created "2023-06-03" @default.
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• W4379094599 date "2023-06-15" @default.
• W4379094599 modified "2023-10-17" @default.
• W4379094599 title "Impact of sociodemographic disadvantage on neurobehavioral outcomes in children with newly diagnosed seizures and their unaffected siblings over 36 months" @default.
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• W4379094599 doi "https://doi.org/10.1111/epi.17672" @default.
• W4379094599 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37264778" @default.
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