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• W4379197318 abstract "To evaluate the efficacy and safety of lidocaine patches in Chinese patients with postherpetic neuralgia (PHN).Patients were randomized to receive lidocaine patches or placebo every day for 4 weeks. Efficacy endpoints included the decrease of analogue scale score (VAS) value at week 4, 2 and 1 and the percentage of patients that achieved a 30% decrease of VAS value. Safety analyses were conducted as well.Two hundred forty Chinese patients were randomized. At week 1, lidocaine patch-treated patients had a higher clinical response versus placebo, and at week 4, the mean (SD) decreases of VAS value compared to the baseline were 14.01 (14.35) in the treatment group and 9.36 (12.03) in the placebo group (p = 0.0088). Overall, the safety profile in the treatment group was consistent with that observed in the placebo group [adverse event (AE) incidence rate: 33.33% versus 37.29%, p = 0.5857].Lidocaine patches resulted in improved clinical response versus placebo in the treatment of PHN patients and were well tolerated." @default.
• W4379197318 created "2023-06-04" @default.
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• W4379197318 date "2023-06-02" @default.
• W4379197318 modified "2023-10-12" @default.
• W4379197318 title "Randomized, Placebo-Controlled, Multicenter Clinical Study on the Efficacy and Safety of Lidocaine Patches in Chinese Patients with Postherpetic Neuralgia" @default.
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• W4379197318 doi "https://doi.org/10.1007/s13555-023-00938-8" @default.
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