Matches in SemOpenAlex for { <https://semopenalex.org/work/W4379332769> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W4379332769 endingPage "e16204" @default.
- W4379332769 startingPage "e16204" @default.
- W4379332769 abstract "e16204 Background: To determine the safety and efficacy of transcatheter arterial chemoembolization with CalliSpheres beads loaded with arsenic trioxide (CBATO-TACE) in the first-line treatment of patients with large (5 cm ≤ maximum diameter＜10 cm) or huge (maximum diameter ≥10 cm) hepatocellular carcinoma (HCC). Methods: Patients were randomly allocated to the CBATO-TACE group and the cTACE group. The primary endpoint was progression-free survival (PFS). The secondary endpoint was overall survival (OS), treatment response, and treatment- related adverse events (TRAEs). The extrahepatic collateral arteries, liver function, and liver fibrosis after the first TACE were also evaluated. Results: From September 2018 to September 2020, a total of 207 patients underwent TACE were consecutively enrolled in this study. The median PFS was 9.5 months (range: 8.0-11.0) in the CBATO group, which was significantly longer than that in the cTACE group (6.0 months, range: 4.0-6.0) ( P< 0.0001). Patients in the CBATO group had a median OS of 22 months (range: 20.0-27.0) compared with 16 months (range:15.0-20.0）in the cTACE group ( P= 0.0084). The most common TRAEs were fever ( P= 0.043), nausea and vomiting ( P= 0.002), which were more observed in the cTACE group. In addition, the progressive disease time, pulmonary metastasis rate ( P= 0.01), the mean number of EHC arteries ( P= 0.01) and average number of TACE sessions ( P= 0.025) were significantly decreased in the CBATO group. Conclusions: CBATO-TACE achieved better therapeutic outcomes and similar safety profile compared to cTACE in large or huge HCC patients. Furthermore, CBATO-TACE was able to reduce extrahepatic collateral arteries production and extrahepatic lung metastasis. Clinical trial information: ChiCTR1800018418 ." @default.
- W4379332769 created "2023-06-05" @default.
- W4379332769 creator A5000286764 @default.
- W4379332769 creator A5011848072 @default.
- W4379332769 creator A5013996193 @default.
- W4379332769 creator A5018383129 @default.
- W4379332769 creator A5019560977 @default.
- W4379332769 creator A5035888073 @default.
- W4379332769 creator A5060365788 @default.
- W4379332769 creator A5076516501 @default.
- W4379332769 creator A5090014574 @default.
- W4379332769 creator A5090608407 @default.
- W4379332769 date "2023-06-01" @default.
- W4379332769 modified "2023-09-26" @default.
- W4379332769 title "Transcatheter arterial chemoembolization using CalliSpheres beads loaded with arsenic trioxide for unresectable large or huge hepatocellular carcinoma: A prospective study." @default.
- W4379332769 doi "https://doi.org/10.1200/jco.2023.41.16_suppl.e16204" @default.
- W4379332769 hasPublicationYear "2023" @default.
- W4379332769 type Work @default.
- W4379332769 citedByCount "0" @default.
- W4379332769 crossrefType "journal-article" @default.
- W4379332769 hasAuthorship W4379332769A5000286764 @default.
- W4379332769 hasAuthorship W4379332769A5011848072 @default.
- W4379332769 hasAuthorship W4379332769A5013996193 @default.
- W4379332769 hasAuthorship W4379332769A5018383129 @default.
- W4379332769 hasAuthorship W4379332769A5019560977 @default.
- W4379332769 hasAuthorship W4379332769A5035888073 @default.
- W4379332769 hasAuthorship W4379332769A5060365788 @default.
- W4379332769 hasAuthorship W4379332769A5076516501 @default.
- W4379332769 hasAuthorship W4379332769A5090014574 @default.
- W4379332769 hasAuthorship W4379332769A5090608407 @default.
- W4379332769 hasConcept C126322002 @default.
- W4379332769 hasConcept C168563851 @default.
- W4379332769 hasConcept C191897082 @default.
- W4379332769 hasConcept C192562407 @default.
- W4379332769 hasConcept C197934379 @default.
- W4379332769 hasConcept C203092338 @default.
- W4379332769 hasConcept C2778019345 @default.
- W4379332769 hasConcept C2778455285 @default.
- W4379332769 hasConcept C2780386689 @default.
- W4379332769 hasConcept C2780580376 @default.
- W4379332769 hasConcept C2780852908 @default.
- W4379332769 hasConcept C502230775 @default.
- W4379332769 hasConcept C71924100 @default.
- W4379332769 hasConcept C90924648 @default.
- W4379332769 hasConceptScore W4379332769C126322002 @default.
- W4379332769 hasConceptScore W4379332769C168563851 @default.
- W4379332769 hasConceptScore W4379332769C191897082 @default.
- W4379332769 hasConceptScore W4379332769C192562407 @default.
- W4379332769 hasConceptScore W4379332769C197934379 @default.
- W4379332769 hasConceptScore W4379332769C203092338 @default.
- W4379332769 hasConceptScore W4379332769C2778019345 @default.
- W4379332769 hasConceptScore W4379332769C2778455285 @default.
- W4379332769 hasConceptScore W4379332769C2780386689 @default.
- W4379332769 hasConceptScore W4379332769C2780580376 @default.
- W4379332769 hasConceptScore W4379332769C2780852908 @default.
- W4379332769 hasConceptScore W4379332769C502230775 @default.
- W4379332769 hasConceptScore W4379332769C71924100 @default.
- W4379332769 hasConceptScore W4379332769C90924648 @default.
- W4379332769 hasFunder F4320321001 @default.
- W4379332769 hasIssue "16_suppl" @default.
- W4379332769 hasLocation W43793327691 @default.
- W4379332769 hasOpenAccess W4379332769 @default.
- W4379332769 hasPrimaryLocation W43793327691 @default.
- W4379332769 hasRelatedWork W1965726515 @default.
- W4379332769 hasRelatedWork W2041128529 @default.
- W4379332769 hasRelatedWork W2164530441 @default.
- W4379332769 hasRelatedWork W2358248846 @default.
- W4379332769 hasRelatedWork W2366360108 @default.
- W4379332769 hasRelatedWork W2383841506 @default.
- W4379332769 hasRelatedWork W243857094 @default.
- W4379332769 hasRelatedWork W2893772422 @default.
- W4379332769 hasRelatedWork W2979514008 @default.
- W4379332769 hasRelatedWork W3031611473 @default.
- W4379332769 hasVolume "41" @default.
- W4379332769 isParatext "false" @default.
- W4379332769 isRetracted "false" @default.
- W4379332769 workType "article" @default.