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- W4379520195 abstract "The myelin sheath is an insulating layer around the nerves of the brain and spinal cord which allows a fast and efficient nerve conduction. Myelin is made of protein and fatty substances and gives protection for the propagation of the electrical impulse. The myelin sheath is formed by oligodendrocytes in the central nervous system (CNS) and by Schwann cells in the peripheral nervous system (PNS). The myelin sheath presents a highly organized structure and expands both radially and longitudinally, but in a different way and with a different composition. Myelin alterations determine the onset of several neuropathies, as the electrical signal can be slowed or stopped. Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) and ras (rat sarcoma)-associated binding proteins (rabs) have been proved to contribute to several aspects regarding the formation of myelin or dysmyelination. Here, I will describe the role of these proteins in regulating membrane trafficking and nerve conduction, myelin biogenesis and maintenance." @default.
- W4379520195 created "2023-06-07" @default.
- W4379520195 creator A5031541740 @default.
- W4379520195 date "2023-06-05" @default.
- W4379520195 modified "2023-10-14" @default.
- W4379520195 title "Role of SNAREs and Rabs in Myelin Regulation" @default.
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- W4379520195 doi "https://doi.org/10.3390/ijms24119772" @default.
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