FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4379523081> ?p ?o ?g. }

• W4379523081 endingPage "318" @default.
• W4379523081 startingPage "318.1" @default.
• W4379523081 abstract "Background Systemic immune inflammatory index (SII) is a new marker of inflammation. SII is associated with increased cancer risk and mortality in cardiovascular and cancer patients. However, the effect of SII on mortality in gout patients is rarely reported in the literature. Objectives To study the relationship between SII level and all-cause mortality in gout patients. Methods This prospective cohort study included participants 20 years or older with gout enrolled from the 2007-2008 through 2017-2018 annual NHANES cycles. The data of mortality and its underlying causes to 31 December 2019 were obtained from the National Death Index records. The SII level was calculated as the platelet counts × neutrophil counts/lymphocyte counts. Gout patients were grouped according to low, middle and high tertile of SII. Generalize linear regression was used to study variables influencing SII. The relationship between SII level and mortality were analyzed by Cox proportional hazards analysis. Results A total of 1334 gout patients were included with median follow-up time 68 months (34 months, 106 months). As shown in the Table 1, gout patients with high SII level were characterized by more having chronic kidney diseases, diabetes mellitus and less fiber intake (P <0.05). The generalized linear model found that SII level was positively correlated with diabetes mellitus (P<0.05), and negatively correlated with men, eGFR, fiber intake (P<0.05). Kaplan Meier survival curve showed that mortality was highest in the high SII group (Figure 1). Cox proportional hazards analysis after multivariable adjustment showed that taking low SII group as the reference group, mortality was elevated in the high SII groups (Table 1). Conclusion High SII is a predictor of all-cause death in gout patients. Table 1. Characteristics of gout patients according to low, middle and high tertile of SII. SII tertile Low (N=445) Middle (N=444) High (N=445) P-value Age, years 60.0(53.0,69.0) 62.0(52.0,70.0) 63.0(54.0,71.0) 0.398 Sex, % 0.407 Male 69.3 (60.1,77.1) 73.1 (67.1,78.3) 66.5(59.8,72.5) Education 0.199 <high school，% 5.0 (3.3,7.5) 5.8 (3.7,8.8) 5.6 (3.9,7.8) High school，% 11.0 (8.0,15.0) 9.1 (6.6,12.4) 10.7 (7.6,14.8) High School Graduate or Equivalent，% 21.3 (16.4,27.2) 23.9 (18.2,30.8) 30.4(24.5,37.0) College and above，% 62.7 (55.7,69.2) 61.2 (54.1,68.0) 53.4(46.5,60.2) Body mass index, kg/m² 30.6(27.0,34.7) 31.2(28.0,35.2) 31.0(27.0,36.4) 0.465 Serum urate (sUA), mg/dL 6.4(5.2,7.4) 6.4(5.5,7.7) 6.6(5.3,7.7) 0.781 Estimated glomerular filtration rate (eGFR), ml/(min·1.73m2) 79.7(63.3,94.0) 78.8(61.5.3,92.8) 73.5(56.6,91.3) 0.060 Chronic kidney disease, % 27.2 (22.0,33.0) 38.9 (32.4,45.9) 40.4(34.4,46.6) 0.004 Cardiovascular disease, % 25.2 (19.8,31.4) 27.5 (22.8,32.8) 30.4(25.4,35.8) 0.387 Diabetes mellitus, % 26.2 (21.9,31.1) 36.7 (29.3,44.7) 38.6(31.8,45.8) 0.018 Hyperlipidemia, % 81.3 (73.6,87.2) 89.2 (85.2,92.1) 83.9(77.6,88.7) 0.075 Hypertension, % 73.7 (67.7,79.0) 75.1 (68.3,80.8) 78.5(72.3,83.6) 0.509 Fiber, g 16.4(10.0,23.3) 14.2(9.5,21.0) 13.2(8.1,19.9) 0.005 Number of death, % 12.1 (9.4,15.4) 15.0 (11.8,19.0) 22.3(18.0,27.3) <0.001 Hazard ratio (95% CI)* 1.0 1.07(0.73,1.58) 1.56(1.01-2.41) - *Hazard ratio analysis were adjusted by age, sex, race, education, BMI, smoking, cardiovascular disease, hyperlipidemia, hypertension and diabetes mellitus, eGFR and dietary covariates. Figure 1. The Kaplan–Meier curves for all-cause mortality by subgroups of SII. REFERENCES: NIL. Acknowledgements: NIL. Disclosure of Interests None Declared." @default.
• W4379523081 created "2023-06-07" @default.
• W4379523081 creator A5032024736 @default.
• W4379523081 creator A5067741522 @default.
• W4379523081 creator A5080298585 @default.
• W4379523081 creator A5085340388 @default.
• W4379523081 date "2023-05-30" @default.
• W4379523081 modified "2023-09-23" @default.
• W4379523081 title "POS0185 SYSTEMIC IMMUNE-INFLAMMATION INDEX TO ALL-CAUSE MORTALITY IN GOUT PATIENTS: NHANES 2007-2018" @default.
• W4379523081 doi "https://doi.org/10.1136/annrheumdis-2023-eular.3874" @default.
• W4379523081 hasPublicationYear "2023" @default.
• W4379523081 type Work @default.
• W4379523081 citedByCount "0" @default.
• W4379523081 crossrefType "journal-article" @default.
• W4379523081 hasAuthorship W4379523081A5032024736 @default.
• W4379523081 hasAuthorship W4379523081A5067741522 @default.
• W4379523081 hasAuthorship W4379523081A5080298585 @default.
• W4379523081 hasAuthorship W4379523081A5085340388 @default.
• W4379523081 hasBestOaLocation W43795230811 @default.
• W4379523081 hasConcept C126322002 @default.
• W4379523081 hasConcept C134018914 @default.
• W4379523081 hasConcept C207103383 @default.
• W4379523081 hasConcept C2777654188 @default.
• W4379523081 hasConcept C2780221984 @default.
• W4379523081 hasConcept C2780402116 @default.
• W4379523081 hasConcept C44249647 @default.
• W4379523081 hasConcept C50382708 @default.
• W4379523081 hasConcept C555293320 @default.
• W4379523081 hasConcept C71924100 @default.
• W4379523081 hasConcept C90924648 @default.
• W4379523081 hasConceptScore W4379523081C126322002 @default.
• W4379523081 hasConceptScore W4379523081C134018914 @default.
• W4379523081 hasConceptScore W4379523081C207103383 @default.
• W4379523081 hasConceptScore W4379523081C2777654188 @default.
• W4379523081 hasConceptScore W4379523081C2780221984 @default.
• W4379523081 hasConceptScore W4379523081C2780402116 @default.
• W4379523081 hasConceptScore W4379523081C44249647 @default.
• W4379523081 hasConceptScore W4379523081C50382708 @default.
• W4379523081 hasConceptScore W4379523081C555293320 @default.
• W4379523081 hasConceptScore W4379523081C71924100 @default.
• W4379523081 hasConceptScore W4379523081C90924648 @default.
• W4379523081 hasIssue "Suppl 1" @default.
• W4379523081 hasLocation W43795230811 @default.
• W4379523081 hasOpenAccess W4379523081 @default.
• W4379523081 hasPrimaryLocation W43795230811 @default.
• W4379523081 hasRelatedWork W1965659650 @default.
• W4379523081 hasRelatedWork W2117571685 @default.
• W4379523081 hasRelatedWork W2122347435 @default.
• W4379523081 hasRelatedWork W2789034072 @default.
• W4379523081 hasRelatedWork W2884628872 @default.
• W4379523081 hasRelatedWork W2888550302 @default.
• W4379523081 hasRelatedWork W2916193034 @default.
• W4379523081 hasRelatedWork W3108721673 @default.
• W4379523081 hasRelatedWork W4225701820 @default.
• W4379523081 hasRelatedWork W4353083550 @default.
• W4379523081 hasVolume "82" @default.
• W4379523081 isParatext "false" @default.
• W4379523081 isRetracted "false" @default.
• W4379523081 workType "article" @default.