FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4379600625> ?p ?o ?g. }

• W4379600625 endingPage "8019" @default.
• W4379600625 startingPage "8005" @default.
• W4379600625 abstract "Abstract Broad-host-range (BHR) plasmids in human gut bacteria are of considerable interest for their ability to mediate horizontal gene transfer (HGT) across large phylogenetic distance. However, the human gut plasmids, especially the BHR plasmids, remain largely unknown. Here, we identified the plasmids in the draft genomes of gut bacterial isolates from Chinese and American donors, resulting in 5372 plasmid-like clusters (PLCs), of which, 820 PLCs (comPLCs) were estimated with &gt; 60% completeness genomes and only 155 (18.9%) were classified to known replicon types (n = 37). We observed that 175 comPLCs had a broad host range across distinct bacterial genera, of which, 71 were detected in at least two human populations of Chinese, American, Spanish, and Danish, and 13 were highly prevalent (&gt;10%) in at least one human population. Haplotype analyses of two widespread PLCs demonstrated their spreading and evolutionary trajectory, suggesting frequent and recent exchanges of the BHR plasmids in environments. In conclusion, we obtained a large collection of plasmid sequences in human gut bacteria and demonstrated that a subset of the BHR plasmids can be transmitted globally, thus facilitating extensive HGT (e.g. antibiotic resistance genes) events. This study highlights the potential implications of the plasmids for global human health." @default.
• W4379600625 created "2023-06-08" @default.
• W4379600625 creator A5033247634 @default.
• W4379600625 creator A5038336906 @default.
• W4379600625 creator A5049439879 @default.
• W4379600625 creator A5052151397 @default.
• W4379600625 creator A5065347293 @default.
• W4379600625 creator A5068708518 @default.
• W4379600625 creator A5080093402 @default.
• W4379600625 date "2023-06-07" @default.
• W4379600625 modified "2023-10-05" @default.
• W4379600625 title "Global transmission of broad-host-range plasmids derived from the human gut microbiome" @default.
• W4379600625 cites W1762378002 @default.
• W4379600625 cites W1946252112 @default.
• W4379600625 cites W1966549106 @default.
• W4379600625 cites W1967134059 @default.
• W4379600625 cites W1979696774 @default.
• W4379600625 cites W1996423252 @default.
• W4379600625 cites W2038043390 @default.
• W4379600625 cites W2045204781 @default.
• W4379600625 cites W2070040136 @default.
• W4379600625 cites W2088861893 @default.
• W4379600625 cites W2092454947 @default.
• W4379600625 cites W2097124003 @default.
• W4379600625 cites W2108929776 @default.
• W4379600625 cites W2113679889 @default.
• W4379600625 cites W2114850508 @default.
• W4379600625 cites W2116913446 @default.
• W4379600625 cites W2119888547 @default.
• W4379600625 cites W2120902911 @default.
• W4379600625 cites W2121980713 @default.
• W4379600625 cites W2124166542 @default.
• W4379600625 cites W2124351063 @default.
• W4379600625 cites W2132926880 @default.
• W4379600625 cites W2142678478 @default.
• W4379600625 cites W2143325926 @default.
• W4379600625 cites W2143485490 @default.
• W4379600625 cites W2151372451 @default.
• W4379600625 cites W2159675211 @default.
• W4379600625 cites W2267957258 @default.
• W4379600625 cites W2513727910 @default.
• W4379600625 cites W2521321100 @default.
• W4379600625 cites W2755331695 @default.
• W4379600625 cites W2756538273 @default.
• W4379600625 cites W2782623083 @default.
• W4379600625 cites W2791729250 @default.
• W4379600625 cites W2803787045 @default.
• W4379600625 cites W2896447123 @default.
• W4379600625 cites W2900102202 @default.
• W4379600625 cites W2912990896 @default.
• W4379600625 cites W2921342657 @default.
• W4379600625 cites W2942757983 @default.
• W4379600625 cites W2949831026 @default.
• W4379600625 cites W2950150251 @default.
• W4379600625 cites W2951254987 @default.
• W4379600625 cites W2951325968 @default.
• W4379600625 cites W2951912016 @default.
• W4379600625 cites W2971887687 @default.
• W4379600625 cites W2975378700 @default.
• W4379600625 cites W2977770083 @default.
• W4379600625 cites W2982531601 @default.
• W4379600625 cites W2999988657 @default.
• W4379600625 cites W3024222188 @default.
• W4379600625 cites W3043497582 @default.
• W4379600625 cites W3055603547 @default.
• W4379600625 cites W3093335355 @default.
• W4379600625 cites W3121744581 @default.
• W4379600625 cites W3133381154 @default.
• W4379600625 cites W3173385890 @default.
• W4379600625 cites W3173711206 @default.
• W4379600625 doi "https://doi.org/10.1093/nar/gkad498" @default.
• W4379600625 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37283060" @default.
• W4379600625 hasPublicationYear "2023" @default.
• W4379600625 type Work @default.
• W4379600625 citedByCount "0" @default.
• W4379600625 crossrefType "journal-article" @default.
• W4379600625 hasAuthorship W4379600625A5033247634 @default.
• W4379600625 hasAuthorship W4379600625A5038336906 @default.
• W4379600625 hasAuthorship W4379600625A5049439879 @default.
• W4379600625 hasAuthorship W4379600625A5052151397 @default.
• W4379600625 hasAuthorship W4379600625A5065347293 @default.
• W4379600625 hasAuthorship W4379600625A5068708518 @default.
• W4379600625 hasAuthorship W4379600625A5080093402 @default.
• W4379600625 hasBestOaLocation W43796006251 @default.
• W4379600625 hasConcept C104317684 @default.
• W4379600625 hasConcept C141231307 @default.
• W4379600625 hasConcept C143121216 @default.
• W4379600625 hasConcept C144024400 @default.
• W4379600625 hasConcept C149923435 @default.
• W4379600625 hasConcept C18103114 @default.
• W4379600625 hasConcept C22744801 @default.
• W4379600625 hasConcept C2908647359 @default.
• W4379600625 hasConcept C54355233 @default.
• W4379600625 hasConcept C86803240 @default.
• W4379600625 hasConcept C89423630 @default.
• W4379600625 hasConcept C92938381 @default.
• W4379600625 hasConceptScore W4379600625C104317684 @default.
• W4379600625 hasConceptScore W4379600625C141231307 @default.

• next