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- W4379619281 endingPage "101787" @default.
- W4379619281 startingPage "101787" @default.
- W4379619281 abstract "Neuroendocrine neoplasms are a unique form of malignancies as they can be accompanied by specific functioning hormonal syndromes that can impair survival and quality of life in patients. Functioning syndromes are defined by the combination of specific clinical signs and symptoms in combination with inappropriately elevated circulating levels of hormones. Clinicians should remain vigilant for the presence of functioning syndromes in neuroendocrine neoplasm patients at presentation as well as during follow-up. The correct diagnostic work-up should be initiated in cases of clinical suspicion of a neuroendocrine neoplasm-associated functioning syndrome. Management of a functional syndrome includes options from supportive, surgical, hormonal and antiproliferative treatment modalities. Here, we review the patient and tumour characteristics for each functioning syndrome that should be taken into account when deciding the optimum treatment strategy in neuroendocrine neoplasm patients." @default.
- W4379619281 created "2023-06-08" @default.
- W4379619281 creator A5023302477 @default.
- W4379619281 creator A5048006075 @default.
- W4379619281 date "2023-06-01" @default.
- W4379619281 modified "2023-09-23" @default.
- W4379619281 title "Effective strategies for adequate control of hormonal secretion in functioning neuroendocrine neoplasms" @default.
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- W4379619281 doi "https://doi.org/10.1016/j.beem.2023.101787" @default.
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