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• W4379646794 abstract "<h3>Background</h3> Mucocutaneous lesions are one of the most characteristic signs of Behçet’s Disease (BD) and are included in different classification criteria <b>[1].</b> <h3>Objectives</h3> To describe the mucocutaneous manifestations and to assess it accordingly to age and sex. <h3>Methods</h3> Descriptive study of a cohort of 120 patients diagnosed with BD from January 1, 1980 to December 31, 2019. Finally, we included 92 patients following the 2014 International Criteria for Behçet’s Disease (ICBD) <b>[2].</b> <h3>Results</h3> 92 patients (45 men/ 47 women) had mucocutaneous involvement. Mean age at diagnosis was (36.3±12.6) years. 27 (29.3%) were young adults (<30 years), 61 (66.3%) middle-aged adults (30-60) and 4 (4.3%) elderly adults (>60 years). The most frequent mucocutaneous manifestations were oral ulcers (OU) (n=92, 97.9%), genital ulcers (GU) (n=69, 73.4%), pseudofolliculitis (n=47, 50%), erythema nodosum-like lesions (EN) (n=28, 29.8%) and Raynaud’s phenomenon (n=2, 2%). OU, GU, EN-like lesions and Raynaud’s phenomenon were more frequent in women. GU and pseudofollicullitis were more frequent in men. No statistical differences were found between sexes (χ² test). Pathergy test was positive in 4 patients. Histopathology of EN-like lesions was performed in 5 patients, 3 (60%) showed septal panniculitis and 2 (40%) vasculitis with neutrophil infiltration, which is a typical pathological finding of EN-like lesion in BD [2]. <b>Table 1</b>. Mucocutaneous lesions divided by age groups are represented in <b>Figure 1</b>. <h3>Conclusion</h3> Identifying characteristic mucocutaneous lesions of BD, as OU, GU, pseudofollicullitis and EN-like lesions may allow early diagnosis and treatment of the disease. There were no gender differences in mucocutaneous lesions. <h3>References</h3> [1]Nakamura K et al, Med (Lausanne). 2021 Feb 1; 7:613432. [2]International Team for the Revision of the International Criteria for Behçet’s Disease (ITR-ICBD). J Eur Acad Dermatol Venereol. 2014 Mar;28(3):338-47. <h3>Acknowledgements:</h3> NIL. <h3>Disclosure of Interests</h3> Carmen Álvarez-Reguera: None declared, Alba Herrero-Morant: None declared, Lara Sanchez-Bilbao: None declared, David Martínez-López: None declared, José Luis Martín-Varillas Grant/research support from: Abbvie, Pfizer, Janssen, Lilly and Celgene., Guillermo Suárez Amorín: None declared, Rosalía Demetrio-Pablo: None declared, Ricardo Blanco Speakers bureau: AbbVie, Pfizer, Roche, Bristol-Myers, Lilly, Janssen, and MSD. Janssen, and MSD., Grant/research support from: AbbVie, MSD, and Roche." @default.
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• W4379646794 date "2023-05-30" @default.
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• W4379646794 title "AB1515 EPIDEMIOLOGY AND CLINICAL FEATURES OF MUCOCUTANEOUS LESIONS IN BEHÇET’S DISEASE: STUDY FROM A COHORT OF 120 PATIENTS IN A REGION IN NORTHERN SPAIN" @default.
• W4379646794 doi "https://doi.org/10.1136/annrheumdis-2023-eular.2587" @default.
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