Matches in SemOpenAlex for { <https://semopenalex.org/work/W4379966098> ?p ?o ?g. }
- W4379966098 abstract "Natural behaviors are a coordinated symphony of motor acts which drive self-induced or reafferent sensory activation. Single sensors only signal presence and magnitude of a sensory cue; they cannot disambiguate exafferent (externally-induced) from reafferent sources. Nevertheless, animals readily differentiate between these sources of sensory signals to make appropriate decisions and initiate adaptive behavioral outcomes. This is mediated by predictive motor signaling mechanisms, which emanate from motor control pathways to sensory processing pathways, but how predictive motor signaling circuits function at the cellular and synaptic level is poorly understood. We use a variety of techniques, including connectomics from both male and female electron microscopy volumes, transcriptomics, neuroanatomical, physiological and behavioral approaches to resolve the network architecture of two pairs of ascending histaminergic neurons (AHNs), which putatively provide predictive motor signals to several sensory and motor neuropil. Both AHN pairs receive input primarily from an overlapping population of descending neurons, many of which drive wing motor output. The two AHN pairs target almost exclusively non-overlapping downstream neural networks including those that process visual, auditory and mechanosensory information as well as networks coordinating wing, haltere, and leg motor output. These results support the conclusion that the AHN pairs multi-task, integrating a large amount of common input, then tile their output in the brain, providing predictive motor signals to non-overlapping sensory networks affecting motor control both directly and indirectly." @default.
- W4379966098 created "2023-06-10" @default.
- W4379966098 creator A5000035161 @default.
- W4379966098 creator A5007319617 @default.
- W4379966098 creator A5015889105 @default.
- W4379966098 creator A5029018726 @default.
- W4379966098 creator A5034821942 @default.
- W4379966098 creator A5043059580 @default.
- W4379966098 creator A5048514347 @default.
- W4379966098 creator A5064386767 @default.
- W4379966098 creator A5068763335 @default.
- W4379966098 creator A5081863770 @default.
- W4379966098 creator A5085845618 @default.
- W4379966098 creator A5086159997 @default.
- W4379966098 creator A5087441093 @default.
- W4379966098 creator A5090392376 @default.
- W4379966098 creator A5091268346 @default.
- W4379966098 date "2023-06-09" @default.
- W4379966098 modified "2023-09-26" @default.
- W4379966098 title "Organization of an Ascending Circuit that Conveys Flight Motor State" @default.
- W4379966098 cites W1022321647 @default.
- W4379966098 cites W1218442431 @default.
- W4379966098 cites W1491075702 @default.
- W4379966098 cites W1605784135 @default.
- W4379966098 cites W1881223776 @default.
- W4379966098 cites W1900719141 @default.
- W4379966098 cites W1903106126 @default.
- W4379966098 cites W1965568388 @default.
- W4379966098 cites W1968331399 @default.
- W4379966098 cites W1968358311 @default.
- W4379966098 cites W1969271050 @default.
- W4379966098 cites W1971265527 @default.
- W4379966098 cites W1978157456 @default.
- W4379966098 cites W1981024652 @default.
- W4379966098 cites W1982013387 @default.
- W4379966098 cites W1985570871 @default.
- W4379966098 cites W1989648264 @default.
- W4379966098 cites W1994295371 @default.
- W4379966098 cites W1998684809 @default.
- W4379966098 cites W1999472091 @default.
- W4379966098 cites W2002322119 @default.
- W4379966098 cites W2002667643 @default.
- W4379966098 cites W2003203157 @default.
- W4379966098 cites W2008897356 @default.
- W4379966098 cites W2021607484 @default.
- W4379966098 cites W2024828917 @default.
- W4379966098 cites W2025185010 @default.
- W4379966098 cites W2025654941 @default.
- W4379966098 cites W2028568903 @default.
- W4379966098 cites W2030688466 @default.
- W4379966098 cites W2032869516 @default.
- W4379966098 cites W2035505151 @default.
- W4379966098 cites W2038689027 @default.
- W4379966098 cites W2039198384 @default.
- W4379966098 cites W2041832698 @default.
- W4379966098 cites W2047454296 @default.
- W4379966098 cites W2048063102 @default.
- W4379966098 cites W2057699169 @default.
- W4379966098 cites W2058082904 @default.
- W4379966098 cites W2058374663 @default.
- W4379966098 cites W2062324661 @default.
- W4379966098 cites W2063408409 @default.
- W4379966098 cites W2067871811 @default.
- W4379966098 cites W2068330517 @default.
- W4379966098 cites W2069385338 @default.
- W4379966098 cites W2069454459 @default.
- W4379966098 cites W2070925479 @default.
- W4379966098 cites W2071714786 @default.
- W4379966098 cites W2073086800 @default.
- W4379966098 cites W2088330265 @default.
- W4379966098 cites W2092098765 @default.
- W4379966098 cites W2093806389 @default.
- W4379966098 cites W2094037592 @default.
- W4379966098 cites W2104034261 @default.
- W4379966098 cites W2104897785 @default.
- W4379966098 cites W2109288660 @default.
- W4379966098 cites W2116955149 @default.
- W4379966098 cites W2119227505 @default.
- W4379966098 cites W2121071682 @default.
- W4379966098 cites W2132998763 @default.
- W4379966098 cites W2137753785 @default.
- W4379966098 cites W2145317060 @default.
- W4379966098 cites W2145890238 @default.
- W4379966098 cites W2158654359 @default.
- W4379966098 cites W2163314583 @default.
- W4379966098 cites W2167279371 @default.
- W4379966098 cites W2174844779 @default.
- W4379966098 cites W2184418779 @default.
- W4379966098 cites W2209916642 @default.
- W4379966098 cites W2233350458 @default.
- W4379966098 cites W2261263381 @default.
- W4379966098 cites W2273916944 @default.
- W4379966098 cites W2298995811 @default.
- W4379966098 cites W2464229795 @default.
- W4379966098 cites W2587139956 @default.
- W4379966098 cites W2614463946 @default.
- W4379966098 cites W2618420889 @default.
- W4379966098 cites W2699457337 @default.
- W4379966098 cites W2739214808 @default.
- W4379966098 cites W2761788149 @default.