Matches in SemOpenAlex for { <https://semopenalex.org/work/W4379982861> ?p ?o ?g. }
- W4379982861 endingPage "102622" @default.
- W4379982861 startingPage "102622" @default.
- W4379982861 abstract "Mammalian chromosomes are organized at different length scales within the cell nucleus. Topologically Associating Domains (TADs) are structural units of 3D genome organization with functions in gene regulation, DNA replication, recombination and repair. Whereas TADs were initially interpreted as insulated domains, recent studies are revealing that these domains should be interpreted as dynamic collections of actively extruding loops. This process of loop extrusion is subsequently blocked at dedicated TAD boundaries, thereby promoting intra-domain interactions over their surroundings. In this review, we discuss how mammalian TAD structure can emerge from this dynamic process and we discuss recent evidence that TAD boundaries can have regulatory functions." @default.
- W4379982861 created "2023-06-10" @default.
- W4379982861 creator A5038339937 @default.
- W4379982861 creator A5046701563 @default.
- W4379982861 date "2023-08-01" @default.
- W4379982861 modified "2023-10-14" @default.
- W4379982861 title "TADs: Dynamic structures to create stable regulatory functions" @default.
- W4379982861 cites W1558882143 @default.
- W4379982861 cites W1831401007 @default.
- W4379982861 cites W1859117663 @default.
- W4379982861 cites W1873772354 @default.
- W4379982861 cites W1965813899 @default.
- W4379982861 cites W1965863160 @default.
- W4379982861 cites W1973062929 @default.
- W4379982861 cites W2007324420 @default.
- W4379982861 cites W2018658338 @default.
- W4379982861 cites W2028022357 @default.
- W4379982861 cites W2032140335 @default.
- W4379982861 cites W2047005748 @default.
- W4379982861 cites W2070021921 @default.
- W4379982861 cites W2090037139 @default.
- W4379982861 cites W2114866946 @default.
- W4379982861 cites W2123564569 @default.
- W4379982861 cites W2159479483 @default.
- W4379982861 cites W2222531233 @default.
- W4379982861 cites W2401568148 @default.
- W4379982861 cites W2567008309 @default.
- W4379982861 cites W2610160407 @default.
- W4379982861 cites W2614144400 @default.
- W4379982861 cites W2757387674 @default.
- W4379982861 cites W2761461280 @default.
- W4379982861 cites W2775505403 @default.
- W4379982861 cites W2800216985 @default.
- W4379982861 cites W2898514070 @default.
- W4379982861 cites W2949389238 @default.
- W4379982861 cites W2950463539 @default.
- W4379982861 cites W2965729444 @default.
- W4379982861 cites W2981928885 @default.
- W4379982861 cites W2989713781 @default.
- W4379982861 cites W2991248607 @default.
- W4379982861 cites W2998161914 @default.
- W4379982861 cites W2998399076 @default.
- W4379982861 cites W3007279945 @default.
- W4379982861 cites W3009045514 @default.
- W4379982861 cites W3035891096 @default.
- W4379982861 cites W3044002183 @default.
- W4379982861 cites W3093374260 @default.
- W4379982861 cites W3094879970 @default.
- W4379982861 cites W3114643239 @default.
- W4379982861 cites W3126332871 @default.
- W4379982861 cites W3132847906 @default.
- W4379982861 cites W3158393751 @default.
- W4379982861 cites W3161556485 @default.
- W4379982861 cites W4225259708 @default.
- W4379982861 cites W4225320261 @default.
- W4379982861 cites W4226081743 @default.
- W4379982861 cites W4226302594 @default.
- W4379982861 cites W4282915758 @default.
- W4379982861 cites W4283010781 @default.
- W4379982861 cites W4285013803 @default.
- W4379982861 cites W4295509862 @default.
- W4379982861 cites W4295907576 @default.
- W4379982861 cites W4298055410 @default.
- W4379982861 cites W4311588897 @default.
- W4379982861 cites W4311662446 @default.
- W4379982861 cites W4318486619 @default.
- W4379982861 cites W4321185941 @default.
- W4379982861 cites W4323825363 @default.
- W4379982861 cites W4323834304 @default.
- W4379982861 cites W4362523504 @default.
- W4379982861 doi "https://doi.org/10.1016/j.sbi.2023.102622" @default.
- W4379982861 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37302180" @default.
- W4379982861 hasPublicationYear "2023" @default.
- W4379982861 type Work @default.
- W4379982861 citedByCount "4" @default.
- W4379982861 countsByYear W43799828612023 @default.
- W4379982861 crossrefType "journal-article" @default.
- W4379982861 hasAuthorship W4379982861A5038339937 @default.
- W4379982861 hasAuthorship W4379982861A5046701563 @default.
- W4379982861 hasBestOaLocation W43799828612 @default.
- W4379982861 hasConcept C104317684 @default.
- W4379982861 hasConcept C111919701 @default.
- W4379982861 hasConcept C121332964 @default.
- W4379982861 hasConcept C134306372 @default.
- W4379982861 hasConcept C141231307 @default.
- W4379982861 hasConcept C165864922 @default.
- W4379982861 hasConcept C2778512757 @default.
- W4379982861 hasConcept C33923547 @default.
- W4379982861 hasConcept C36503486 @default.
- W4379982861 hasConcept C41008148 @default.
- W4379982861 hasConcept C54355233 @default.
- W4379982861 hasConcept C552990157 @default.
- W4379982861 hasConcept C70721500 @default.
- W4379982861 hasConcept C73573662 @default.
- W4379982861 hasConcept C86803240 @default.
- W4379982861 hasConcept C98045186 @default.
- W4379982861 hasConceptScore W4379982861C104317684 @default.
- W4379982861 hasConceptScore W4379982861C111919701 @default.