Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380048706> ?p ?o ?g. }
- W4380048706 endingPage "35" @default.
- W4380048706 startingPage "35" @default.
- W4380048706 abstract "The ribosome is one of the largest complexes in the cell. Adding to its complexity are more than 200 RNA modification sites present on ribosomal RNAs (rRNAs) in a single human ribosome. These modifications occur in functionally important regions of the rRNA molecule, and they are vital for ribosome function and proper gene expression. Until recent technological advancements, the study of rRNA modifications and their profiles has been extremely laborious, leaving many questions unanswered. Small nucleolar RNAs (snoRNAs) are non-coding RNAs that facilitate and dictate the specificity of rRNA modification deposition, making them an attractive target for ribosome modulation. Here, we propose that through the mapping of rRNA modification profiles, we can identify cell-specific modifications with high therapeutic potential. We also describe the challenges of achieving the targeting specificity needed to implement snoRNAs as therapeutic targets in cancers." @default.
- W4380048706 created "2023-06-10" @default.
- W4380048706 creator A5013619132 @default.
- W4380048706 creator A5092125754 @default.
- W4380048706 date "2023-06-08" @default.
- W4380048706 modified "2023-09-30" @default.
- W4380048706 title "Small Nucleolar (Sno)RNA: Therapy Lays in Translation" @default.
- W4380048706 cites W1984965097 @default.
- W4380048706 cites W1996860050 @default.
- W4380048706 cites W2014881329 @default.
- W4380048706 cites W2027283441 @default.
- W4380048706 cites W2040743013 @default.
- W4380048706 cites W2041527069 @default.
- W4380048706 cites W2052322311 @default.
- W4380048706 cites W20619123 @default.
- W4380048706 cites W2087249772 @default.
- W4380048706 cites W2092915328 @default.
- W4380048706 cites W2115222513 @default.
- W4380048706 cites W2118633853 @default.
- W4380048706 cites W2121069903 @default.
- W4380048706 cites W2126360553 @default.
- W4380048706 cites W2129718981 @default.
- W4380048706 cites W2129874158 @default.
- W4380048706 cites W2133281227 @default.
- W4380048706 cites W2171707557 @default.
- W4380048706 cites W2382893801 @default.
- W4380048706 cites W2681714461 @default.
- W4380048706 cites W2742584148 @default.
- W4380048706 cites W2753767186 @default.
- W4380048706 cites W2754113619 @default.
- W4380048706 cites W2867990590 @default.
- W4380048706 cites W2891167139 @default.
- W4380048706 cites W2903926301 @default.
- W4380048706 cites W2904017395 @default.
- W4380048706 cites W2910341377 @default.
- W4380048706 cites W2914869182 @default.
- W4380048706 cites W2963537251 @default.
- W4380048706 cites W2967001684 @default.
- W4380048706 cites W2975526474 @default.
- W4380048706 cites W2979751848 @default.
- W4380048706 cites W2984219698 @default.
- W4380048706 cites W2994632666 @default.
- W4380048706 cites W3008188839 @default.
- W4380048706 cites W3082366190 @default.
- W4380048706 cites W3088559610 @default.
- W4380048706 cites W3113325921 @default.
- W4380048706 cites W3136384251 @default.
- W4380048706 cites W3165649127 @default.
- W4380048706 cites W3175292432 @default.
- W4380048706 cites W3178456908 @default.
- W4380048706 cites W3191464459 @default.
- W4380048706 cites W3207542540 @default.
- W4380048706 cites W4214717665 @default.
- W4380048706 cites W4221000712 @default.
- W4380048706 cites W4245613016 @default.
- W4380048706 cites W4247897378 @default.
- W4380048706 cites W4280506442 @default.
- W4380048706 cites W4283167167 @default.
- W4380048706 cites W4293084919 @default.
- W4380048706 cites W4296808020 @default.
- W4380048706 cites W4306793037 @default.
- W4380048706 cites W574760894 @default.
- W4380048706 doi "https://doi.org/10.3390/ncrna9030035" @default.
- W4380048706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37368335" @default.
- W4380048706 hasPublicationYear "2023" @default.
- W4380048706 type Work @default.
- W4380048706 citedByCount "0" @default.
- W4380048706 crossrefType "journal-article" @default.
- W4380048706 hasAuthorship W4380048706A5013619132 @default.
- W4380048706 hasAuthorship W4380048706A5092125754 @default.
- W4380048706 hasBestOaLocation W43800487061 @default.
- W4380048706 hasConcept C104317684 @default.
- W4380048706 hasConcept C105580179 @default.
- W4380048706 hasConcept C149364088 @default.
- W4380048706 hasConcept C179255354 @default.
- W4380048706 hasConcept C194993378 @default.
- W4380048706 hasConcept C54355233 @default.
- W4380048706 hasConcept C67705224 @default.
- W4380048706 hasConcept C67905577 @default.
- W4380048706 hasConcept C70721500 @default.
- W4380048706 hasConcept C86803240 @default.
- W4380048706 hasConcept C88478588 @default.
- W4380048706 hasConcept C95444343 @default.
- W4380048706 hasConcept C98098607 @default.
- W4380048706 hasConceptScore W4380048706C104317684 @default.
- W4380048706 hasConceptScore W4380048706C105580179 @default.
- W4380048706 hasConceptScore W4380048706C149364088 @default.
- W4380048706 hasConceptScore W4380048706C179255354 @default.
- W4380048706 hasConceptScore W4380048706C194993378 @default.
- W4380048706 hasConceptScore W4380048706C54355233 @default.
- W4380048706 hasConceptScore W4380048706C67705224 @default.
- W4380048706 hasConceptScore W4380048706C67905577 @default.
- W4380048706 hasConceptScore W4380048706C70721500 @default.
- W4380048706 hasConceptScore W4380048706C86803240 @default.
- W4380048706 hasConceptScore W4380048706C88478588 @default.
- W4380048706 hasConceptScore W4380048706C95444343 @default.
- W4380048706 hasConceptScore W4380048706C98098607 @default.
- W4380048706 hasFunder F4320322252 @default.