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- W4380050093 abstract "Esophageal cancer is a prevalent tumor of the digestive tract worldwide. The detection rate of early-stage esophageal cancer is very low, and most patients are diagnosed with metastasis. Metastasis of esophageal cancer mainly includes direct diffusion metastasis, hematogenous metastasis, and lymphatic metastasis. This article reviews the metabolic process of esophageal cancer metastasis and the mechanisms by which M2 macrophages, CAF, regulatory T cells, and their released cytokines, including chemokines, interleukins, and growth factors, form an immune barrier to the anti-tumor immune response mediated by CD8+ T cells, impeding their ability to kill tumor cells during tumor immune escape. The effect of Ferroptosis on the metastasis of esophageal cancer is briefly mentioned. Moreover, the paper also summarizes common drugs and research directions in chemotherapy, immunotherapy, and targeted therapy for advanced metastatic esophageal cancer. This review aims to serve as a foundation for further investigations into the mechanism and management of esophageal cancer metastasis." @default.
- W4380050093 created "2023-06-10" @default.
- W4380050093 creator A5003463555 @default.
- W4380050093 creator A5041740955 @default.
- W4380050093 creator A5049960776 @default.
- W4380050093 creator A5079491978 @default.
- W4380050093 date "2023-06-08" @default.
- W4380050093 modified "2023-09-29" @default.
- W4380050093 title "Mechanisms of esophageal cancer metastasis and treatment progress" @default.
- W4380050093 cites W1576773659 @default.
- W4380050093 cites W1672626186 @default.
- W4380050093 cites W1710493764 @default.
- W4380050093 cites W1913537710 @default.
- W4380050093 cites W1922959497 @default.
- W4380050093 cites W1967184464 @default.
- W4380050093 cites W1975113490 @default.
- W4380050093 cites W1975426777 @default.
- W4380050093 cites W1982669563 @default.
- W4380050093 cites W1983575915 @default.
- W4380050093 cites W1984621939 @default.
- W4380050093 cites W1993913242 @default.
- W4380050093 cites W1996964551 @default.
- W4380050093 cites W2002879831 @default.
- W4380050093 cites W2004785781 @default.
- W4380050093 cites W2007513287 @default.
- W4380050093 cites W2028060445 @default.
- W4380050093 cites W2038963002 @default.
- W4380050093 cites W2043249221 @default.
- W4380050093 cites W2045126684 @default.
- W4380050093 cites W2046284161 @default.
- W4380050093 cites W2046764077 @default.
- W4380050093 cites W2049185799 @default.
- W4380050093 cites W2049312927 @default.
- W4380050093 cites W2051766264 @default.
- W4380050093 cites W2053829861 @default.
- W4380050093 cites W2054013276 @default.
- W4380050093 cites W2056265598 @default.
- W4380050093 cites W2058648826 @default.
- W4380050093 cites W2069391739 @default.
- W4380050093 cites W2084824326 @default.
- W4380050093 cites W2097471654 @default.
- W4380050093 cites W2097820456 @default.
- W4380050093 cites W2098308961 @default.
- W4380050093 cites W2109495319 @default.
- W4380050093 cites W2109658199 @default.
- W4380050093 cites W2109811105 @default.
- W4380050093 cites W2116011814 @default.
- W4380050093 cites W2116488987 @default.
- W4380050093 cites W2117450795 @default.
- W4380050093 cites W2121870777 @default.
- W4380050093 cites W2127309607 @default.
- W4380050093 cites W2128484344 @default.
- W4380050093 cites W2129353670 @default.
- W4380050093 cites W2132002483 @default.
- W4380050093 cites W2137141910 @default.
- W4380050093 cites W2149255571 @default.
- W4380050093 cites W2159069780 @default.
- W4380050093 cites W2162616129 @default.
- W4380050093 cites W2164701887 @default.
- W4380050093 cites W2165904964 @default.
- W4380050093 cites W2190836196 @default.
- W4380050093 cites W2221426810 @default.
- W4380050093 cites W2290262760 @default.
- W4380050093 cites W2292907750 @default.
- W4380050093 cites W2327628688 @default.
- W4380050093 cites W2405276155 @default.
- W4380050093 cites W2412932050 @default.
- W4380050093 cites W2433756862 @default.
- W4380050093 cites W2468218000 @default.
- W4380050093 cites W2477234116 @default.
- W4380050093 cites W2515945623 @default.
- W4380050093 cites W2518249323 @default.
- W4380050093 cites W2544529171 @default.
- W4380050093 cites W2560156174 @default.
- W4380050093 cites W2561926137 @default.
- W4380050093 cites W2563470051 @default.
- W4380050093 cites W2567639438 @default.
- W4380050093 cites W2588831365 @default.
- W4380050093 cites W2595770436 @default.
- W4380050093 cites W2604478613 @default.
- W4380050093 cites W2618098950 @default.
- W4380050093 cites W2618549007 @default.
- W4380050093 cites W2622526068 @default.
- W4380050093 cites W2626773261 @default.
- W4380050093 cites W2736078726 @default.
- W4380050093 cites W2752476672 @default.
- W4380050093 cites W2765943070 @default.
- W4380050093 cites W2771395225 @default.
- W4380050093 cites W2774029267 @default.
- W4380050093 cites W2785934310 @default.
- W4380050093 cites W2793716456 @default.
- W4380050093 cites W2795686288 @default.
- W4380050093 cites W2795734554 @default.
- W4380050093 cites W2799822179 @default.
- W4380050093 cites W2808751821 @default.
- W4380050093 cites W2886256853 @default.
- W4380050093 cites W2899783597 @default.
- W4380050093 cites W2902604343 @default.
- W4380050093 cites W2903127846 @default.
- W4380050093 cites W2911515300 @default.