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• W4380051617 abstract "Recently, genuine motor abnormalities have been recognized as prodromal and predictive signs of psychosis onset and progression. Therefore, physical exercise could represent a potentially relevant clinical tool in promoting the reshaping of neural connections in motor circuitry. The aim of this review is to provide an overview of the literature on neuroimaging findings as a result of physical treatment in psychosis cohorts. Twenty-one studies, all research articles, were included and discussed in this narrative review. Here, we first outlined how the psychotic brain is susceptible to structural plastic changes after aerobic physical training in pathognomic brain areas (i.e., temporal, hippocampal and parahippocampal regions). Secondly, we focused on functional changes, both region-specific and in terms of connections, to gain insights into the involvement of distant but inter-related neural regions in the plastic process occurring after treatment. Third, we attempted to bridge neural plastic changes occurring after physical interventions with clinical and cognitive outcomes of psychotic patients in order to assess the relevance of such neural reshaping in the psychiatric rehabilitation field. In conclusion, we suggest that the current state of the art is presenting physical intervention as effective in promoting neural changes for patients with psychosis; it is not only useful at the onset of the pathology but also in improving the course of the illness and its functional outcome. However, more evidence is needed to improve our knowledge of the efficacy of physical exercise in plastically reorganizing the psychotic brain in the long term, especially within regions lacking specific investigations, such as motor circuitry." @default.
• W4380051617 created "2023-06-10" @default.
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• W4380051617 date "2023-06-07" @default.
• W4380051617 modified "2023-09-29" @default.
• W4380051617 title "The Effect of Physical Exercise on People with Psychosis: A Qualitative Critical Review of Neuroimaging Findings" @default.
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• W4380051617 doi "https://doi.org/10.3390/brainsci13060923" @default.
• W4380051617 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37371403" @default.
• W4380051617 hasPublicationYear "2023" @default.
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