FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380052437> ?p ?o ?g. }

• W4380052437 endingPage "1706" @default.
• W4380052437 startingPage "1699" @default.
• W4380052437 abstract "Perioperative multimodal analgesia can prevent chronic pain after breast cancer surgery. This study aimed to investigate the efficacy of combined perioperative oral pregabalin and postoperative esketamine in preventing chronic pain after breast cancer surgery.Ninety patients undergoing elective breast cancer surgery were randomized into the combined pregabalin and esketamine group (EP group) and the general anesthesia alone group (Control group). The EP group received 150 mg of oral pregabalin 1 h before surgery and twice daily for seven days postoperatively, and a patient-controlled analgesia pump after surgery that delivered 100 μg sufentanil + 1.25 mg/kg esketamine + 4 mg tropisetron in 100 mL saline solution intravenously. The Control group received placebo capsules before and after the surgery and routine postoperative analgesia (100 μg sufentanil + 4 mg tropisetron in 100 mL saline solution). The primary outcome was the incidence of chronic pain three and six months after surgery. Secondary outcomes included acute postoperative pain, postoperative opioid consumption, and incidence of adverse events.The incidence of chronic pain in the EP group was significantly lower than in the Control group three (14.3% vs 46.3%, P = 0.005) and six (7.1% vs 31.7%, P = 0.009) months postoperatively. The rest numerical rating scale (NRS) pain scores 1-3 days postoperatively and coughing NRS pain scores 1-7 days postoperatively in the EP group were significantly lower than in the Control group (all P ˂ 0.05). The cumulative sufentanil consumption in the EP group during postoperative 0-12, 12-24, and 24-48, 0-24, and 0-48 hours were significantly lower than in the Control group (all P ˂ 0.05).Combined perioperative oral pregabalin and postoperative esketamine effectively prevented chronic pain after breast cancer surgery, improved acute postoperative pain, and reduced postoperative opioid consumption." @default.
• W4380052437 created "2023-06-10" @default.
• W4380052437 creator A5004594993 @default.
• W4380052437 creator A5012527696 @default.
• W4380052437 creator A5021935765 @default.
• W4380052437 creator A5034284013 @default.
• W4380052437 creator A5058200030 @default.
• W4380052437 creator A5062895384 @default.
• W4380052437 date "2023-06-01" @default.
• W4380052437 modified "2023-10-14" @default.
• W4380052437 title "Perioperative Administration of Pregabalin and Esketamine to Prevent Chronic Pain After Breast Cancer Surgery: A Randomized Controlled Trial" @default.
• W4380052437 cites W1981701335 @default.
• W4380052437 cites W2008023699 @default.
• W4380052437 cites W2057964296 @default.
• W4380052437 cites W2100082403 @default.
• W4380052437 cites W2176782486 @default.
• W4380052437 cites W2312745410 @default.
• W4380052437 cites W2325307851 @default.
• W4380052437 cites W2325474008 @default.
• W4380052437 cites W2472656837 @default.
• W4380052437 cites W2484403668 @default.
• W4380052437 cites W2512498541 @default.
• W4380052437 cites W2517126092 @default.
• W4380052437 cites W2620353503 @default.
• W4380052437 cites W2622856690 @default.
• W4380052437 cites W2800943038 @default.
• W4380052437 cites W2806113917 @default.
• W4380052437 cites W2895965163 @default.
• W4380052437 cites W2907714641 @default.
• W4380052437 cites W2913855113 @default.
• W4380052437 cites W2919081889 @default.
• W4380052437 cites W2947848164 @default.
• W4380052437 cites W3005233737 @default.
• W4380052437 cites W3087892568 @default.
• W4380052437 cites W3120401562 @default.
• W4380052437 cites W3157519654 @default.
• W4380052437 cites W4211048968 @default.
• W4380052437 cites W4291397432 @default.
• W4380052437 doi "https://doi.org/10.2147/dddt.s413273" @default.
• W4380052437 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37313456" @default.
• W4380052437 hasPublicationYear "2023" @default.
• W4380052437 type Work @default.
• W4380052437 citedByCount "1" @default.
• W4380052437 crossrefType "journal-article" @default.
• W4380052437 hasAuthorship W4380052437A5004594993 @default.
• W4380052437 hasAuthorship W4380052437A5012527696 @default.
• W4380052437 hasAuthorship W4380052437A5021935765 @default.
• W4380052437 hasAuthorship W4380052437A5034284013 @default.
• W4380052437 hasAuthorship W4380052437A5058200030 @default.
• W4380052437 hasAuthorship W4380052437A5062895384 @default.
• W4380052437 hasBestOaLocation W43800524371 @default.
• W4380052437 hasConcept C121608353 @default.
• W4380052437 hasConcept C126322002 @default.
• W4380052437 hasConcept C141071460 @default.
• W4380052437 hasConcept C168563851 @default.
• W4380052437 hasConcept C170493617 @default.
• W4380052437 hasConcept C2776468701 @default.
• W4380052437 hasConcept C2776885963 @default.
• W4380052437 hasConcept C2777019824 @default.
• W4380052437 hasConcept C2777704003 @default.
• W4380052437 hasConcept C2778144076 @default.
• W4380052437 hasConcept C2778300832 @default.
• W4380052437 hasConcept C2780120127 @default.
• W4380052437 hasConcept C2780795376 @default.
• W4380052437 hasConcept C31174226 @default.
• W4380052437 hasConcept C42219234 @default.
• W4380052437 hasConcept C530470458 @default.
• W4380052437 hasConcept C71924100 @default.
• W4380052437 hasConceptScore W4380052437C121608353 @default.
• W4380052437 hasConceptScore W4380052437C126322002 @default.
• W4380052437 hasConceptScore W4380052437C141071460 @default.
• W4380052437 hasConceptScore W4380052437C168563851 @default.
• W4380052437 hasConceptScore W4380052437C170493617 @default.
• W4380052437 hasConceptScore W4380052437C2776468701 @default.
• W4380052437 hasConceptScore W4380052437C2776885963 @default.
• W4380052437 hasConceptScore W4380052437C2777019824 @default.
• W4380052437 hasConceptScore W4380052437C2777704003 @default.
• W4380052437 hasConceptScore W4380052437C2778144076 @default.
• W4380052437 hasConceptScore W4380052437C2778300832 @default.
• W4380052437 hasConceptScore W4380052437C2780120127 @default.
• W4380052437 hasConceptScore W4380052437C2780795376 @default.
• W4380052437 hasConceptScore W4380052437C31174226 @default.
• W4380052437 hasConceptScore W4380052437C42219234 @default.
• W4380052437 hasConceptScore W4380052437C530470458 @default.
• W4380052437 hasConceptScore W4380052437C71924100 @default.
• W4380052437 hasLocation W43800524371 @default.
• W4380052437 hasLocation W43800524372 @default.
• W4380052437 hasLocation W43800524373 @default.
• W4380052437 hasOpenAccess W4380052437 @default.
• W4380052437 hasPrimaryLocation W43800524371 @default.
• W4380052437 hasRelatedWork W1977920092 @default.
• W4380052437 hasRelatedWork W2007588653 @default.
• W4380052437 hasRelatedWork W2031649560 @default.
• W4380052437 hasRelatedWork W2276670917 @default.
• W4380052437 hasRelatedWork W2373221152 @default.
• W4380052437 hasRelatedWork W2441917732 @default.
• W4380052437 hasRelatedWork W2808070933 @default.
• W4380052437 hasRelatedWork W2995547879 @default.

• next