FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380080416> ?p ?o ?g. }

• W4380080416 endingPage "3113" @default.
• W4380080416 startingPage "3113" @default.
• W4380080416 abstract "Gastric cancer has a poor prognosis and involves metastasis to the peritoneum in over 40% of patients. The optimal treatment modalities have not been established for gastric cancer patients with peritoneal carcinomatosis (GC/PC). Although studies have reported favourable prognostic factors, these have yet to be incorporated into treatment guidelines. Hence, our review aims to appraise the latest diagnostic and treatment developments in managing GC/PC.A systematic review of the literature was performed using MEDLINE, EMBASE, the Cochrane Review, and Scopus databases. Articles were evaluated for the use of hyperthermic intraperitoneal chemotherapy (HIPEC) and pressurised intraperitoneal aerosolised chemotherapy (PIPAC) in GC/PC. A meta-analysis of studies reporting on overall survival (OS) in HIPEC and comparing the extent of cytoreduction as a prognostic factor was also carried out.The database search yielded a total of 2297 studies. Seventeen studies were included in the qualitative and quantitative analyses. Eight studies reported the short-term OS at 1 year as the primary outcome measure, and our analysis showed a significantly higher OS for the HIPEC/CRS cohort compared to the CRS cohort (pooled OR = 0.53; p = 0.0005). This effect persisted longer term at five years as well (pooled OR = 0.52; p < 0.0001). HIPEC and CRS also showed a longer median OS compared to CRS (pooled SMD = 0.61; p < 0.00001). Three studies reporting on PIPAC demonstrated a pooled OS of 10.3 (2.2) months. Prognostic factors for longer OS include a more complete cytoreduction (pooled OR = 5.35; p < 0.00001), which correlated with a peritoneal carcinomatosis index below 7.Novel treatment strategies, such as HIPEC and PIPAC, are promising in the management of GC/PC. Further work is necessary to define their role within the treatment algorithm and identify relevant prognostic factors that will assist patient selection." @default.
• W4380080416 created "2023-06-10" @default.
• W4380080416 creator A5029868483 @default.
• W4380080416 creator A5030729362 @default.
• W4380080416 creator A5059825983 @default.
• W4380080416 date "2023-06-08" @default.
• W4380080416 modified "2023-10-03" @default.
• W4380080416 title "Novel Multi-Modal Therapies and Their Prognostic Potential in Gastric Cancer" @default.
• W4380080416 cites W1537972189 @default.
• W4380080416 cites W17791541 @default.
• W4380080416 cites W1853593785 @default.
• W4380080416 cites W1978904933 @default.
• W4380080416 cites W1992677330 @default.
• W4380080416 cites W1993145790 @default.
• W4380080416 cites W2004576106 @default.
• W4380080416 cites W2004607039 @default.
• W4380080416 cites W2008361031 @default.
• W4380080416 cites W2008906047 @default.
• W4380080416 cites W2029469088 @default.
• W4380080416 cites W2036542308 @default.
• W4380080416 cites W2057243823 @default.
• W4380080416 cites W2057849399 @default.
• W4380080416 cites W2061154403 @default.
• W4380080416 cites W2061256992 @default.
• W4380080416 cites W2064936790 @default.
• W4380080416 cites W2081516783 @default.
• W4380080416 cites W2089194878 @default.
• W4380080416 cites W2093696966 @default.
• W4380080416 cites W2107037361 @default.
• W4380080416 cites W2114163378 @default.
• W4380080416 cites W2127231441 @default.
• W4380080416 cites W2155960053 @default.
• W4380080416 cites W2168604990 @default.
• W4380080416 cites W2171531063 @default.
• W4380080416 cites W2197869810 @default.
• W4380080416 cites W2251541509 @default.
• W4380080416 cites W2299088199 @default.
• W4380080416 cites W2398159531 @default.
• W4380080416 cites W2466009129 @default.
• W4380080416 cites W2608748193 @default.
• W4380080416 cites W2613543961 @default.
• W4380080416 cites W2742957334 @default.
• W4380080416 cites W2777030709 @default.
• W4380080416 cites W2874953668 @default.
• W4380080416 cites W2893598005 @default.
• W4380080416 cites W2903280242 @default.
• W4380080416 cites W2942860188 @default.
• W4380080416 cites W2945459534 @default.
• W4380080416 cites W2946079442 @default.
• W4380080416 cites W2950495184 @default.
• W4380080416 cites W2966164240 @default.
• W4380080416 cites W2973951972 @default.
• W4380080416 cites W3004076032 @default.
• W4380080416 cites W3006084451 @default.
• W4380080416 cites W3032163077 @default.
• W4380080416 cites W3033123563 @default.
• W4380080416 cites W3034849107 @default.
• W4380080416 cites W3081802792 @default.
• W4380080416 cites W3089211305 @default.
• W4380080416 cites W3118615836 @default.
• W4380080416 cites W3128646645 @default.
• W4380080416 cites W3183971326 @default.
• W4380080416 cites W3211809215 @default.
• W4380080416 cites W33255888 @default.
• W4380080416 cites W4231424126 @default.
• W4380080416 cites W4250948394 @default.
• W4380080416 doi "https://doi.org/10.3390/cancers15123113" @default.
• W4380080416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37370723" @default.
• W4380080416 hasPublicationYear "2023" @default.
• W4380080416 type Work @default.
• W4380080416 citedByCount "0" @default.
• W4380080416 crossrefType "journal-article" @default.
• W4380080416 hasAuthorship W4380080416A5029868483 @default.
• W4380080416 hasAuthorship W4380080416A5030729362 @default.
• W4380080416 hasAuthorship W4380080416A5059825983 @default.
• W4380080416 hasBestOaLocation W43800804161 @default.
• W4380080416 hasConcept C121608353 @default.
• W4380080416 hasConcept C126322002 @default.
• W4380080416 hasConcept C141071460 @default.
• W4380080416 hasConcept C143998085 @default.
• W4380080416 hasConcept C2776694085 @default.
• W4380080416 hasConcept C2779458272 @default.
• W4380080416 hasConcept C2780427987 @default.
• W4380080416 hasConcept C2994223192 @default.
• W4380080416 hasConcept C71924100 @default.
• W4380080416 hasConcept C72563966 @default.
• W4380080416 hasConcept C95190672 @default.
• W4380080416 hasConceptScore W4380080416C121608353 @default.
• W4380080416 hasConceptScore W4380080416C126322002 @default.
• W4380080416 hasConceptScore W4380080416C141071460 @default.
• W4380080416 hasConceptScore W4380080416C143998085 @default.
• W4380080416 hasConceptScore W4380080416C2776694085 @default.
• W4380080416 hasConceptScore W4380080416C2779458272 @default.
• W4380080416 hasConceptScore W4380080416C2780427987 @default.
• W4380080416 hasConceptScore W4380080416C2994223192 @default.
• W4380080416 hasConceptScore W4380080416C71924100 @default.
• W4380080416 hasConceptScore W4380080416C72563966 @default.
• W4380080416 hasConceptScore W4380080416C95190672 @default.

• next