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- W4380083012 abstract "Today, in the pharmaceutical industry, many manufacturers produce so-called combined drugs containing 2 or 3 or more active ingredients. There are many reviews and studies in the world literature proving that most combinations, in contrast to sequential administration, often have a more pronounced synergistic effect of combined drugs. The use of such therapy increases patient compliance, while at the same time causing positive pharmacokinetic and other effects inherent in the combination, providing the clinician with new opportunities in the treatment of infections. Although the combination of fluoroquinolone and fixed-dose nitroimidazole derivatives is not as widely used in clinical practice, we present a review of Simprazole®, a combination of ciprofloxacin and ornidazole, analyzing the available data on clinical use and possible prospects that new drug." @default.
- W4380083012 created "2023-06-10" @default.
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- W4380083012 date "2023-06-08" @default.
- W4380083012 modified "2023-09-27" @default.
- W4380083012 title "Prospects for use of combined antibacterial drugs. Simprazol®: When whole is greater than sum" @default.
- W4380083012 cites W2987180427 @default.
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- W4380083012 doi "https://doi.org/10.33667/2078-5631-2023-6-29-32" @default.
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