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• W4380084825 abstract "Atrial fibrillation (AF) is a highly prevalent disease in the United States and globally. 1 Chugh SS Havmoeller R Narayanan K Singh D Rienstra M Benjamin EJ Gillum RF Kim YH McAnulty Jr, JH Zheng ZJ Forouzanfar MH Naghavi M Mensah GA Ezzati M Murray CJ. Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study. Circulation. 2014; 129: 837-847 Google Scholar Studies have shown aggressive risk factor (RF) management including sustained weight loss is associated with significant reduction of AF burden, maintenance of sinus rhythm, and improved event-free survival. 2 Pathak RK Middeldorp ME Meredith M Mehta AB Mahajan R Wong CX Twomey D Elliott AD Kalman JM Abhayaratna WP Lau DH Sanders P. Long-term effect of goal-directed weight management in an atrial fibrillation cohort: a long-term follow-up study (LEGACY). J Am Coll Cardiol. 2015; 65: 2159-2169 Google Scholar ,3 Pathak RK Middeldorp ME Lau DH Mehta AB Mahajan R Twomey D Alasady M Hanley L Antic NA McEvoy RD Kalman JM Abhayaratna WP Sanders P. Aggressive risk factor reduction study for atrial fibrillation and implications for the outcome of ablation: the ARREST-AF cohort study. J Am Coll Cardiol. 2014; 64: 2222-2231 Google Scholar These studies primarily included patients with higher body mass index (BMI). 2 Pathak RK Middeldorp ME Meredith M Mehta AB Mahajan R Wong CX Twomey D Elliott AD Kalman JM Abhayaratna WP Lau DH Sanders P. Long-term effect of goal-directed weight management in an atrial fibrillation cohort: a long-term follow-up study (LEGACY). J Am Coll Cardiol. 2015; 65: 2159-2169 Google Scholar ,3 Pathak RK Middeldorp ME Lau DH Mehta AB Mahajan R Twomey D Alasady M Hanley L Antic NA McEvoy RD Kalman JM Abhayaratna WP Sanders P. Aggressive risk factor reduction study for atrial fibrillation and implications for the outcome of ablation: the ARREST-AF cohort study. J Am Coll Cardiol. 2014; 64: 2222-2231 Google Scholar Another study indicated that aggressive lifestyle modifications in patients with metabolic syndrome and obstructive sleep apnea (OSA) provided a comparable arrhythmia-free survival to that of patients who underwent repeat ablation. 4 Mohanty S Mohanty P DI Biase L Bai R Trivedi C Santangeli P Santoro F Hongo R Hao S Beheiry S Burkhardt D Gallinghouse JG Horton R Sanchez JE Bailey S Hranitzky PM Zagrodzky J Natale A. Long-term outcome of catheter ablation in atrial fibrillation patients with coexistent metabolic syndrome and obstructive sleep apnea: impact of repeat procedures versus lifestyle changes. J Cardiovasc Electrophysiol. 2014; 25: 930-938 Google Scholar Although catheter ablation is a safe and effective procedure for maintaining sinus rhythm or decreasing the AF burden, the long-term benefits may diminish over time. The study by Ganesan et al 5 Ganesan AN Shipp NJ Brooks AG Kuklik P Lau DH Lim HS Sullivan T Roberts-Thomson KC Sanders P. Long-term outcomes of catheter ablation of atrial fibrillation: a systematic review and meta-analysis. J Am Heart Assoc. 2013; 2e004549 Google Scholar showed a single-procedure freedom from atrial arrhythmia with a mean follow-up ≥24 months after the index procedure was 53.1%. Therefore, RF modification plays a central role in preventing recurrence of AF, including patients who underwent AF ablation. The 2019 updated American College of Cardiology/American Heart Association/Heart Rhythm Society guidelines give a class I recommendation for weight loss, combined with other RF modification, to reduce AF burden and symptom severity in patients with overweight and obesity and with AF. 6 January CT Wann LS Calkins H Chen LY Cigarroa JE Cleveland Jr, JC Ellinor PT Ezekowitz MD Field ME Furie KL Heidenreich PA Murray KT Shea JB Tracy CM Yancy CW. 2019 AHA/ACC/HRS focused update of the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. 2019; 140: e125-e151 Google Scholar" @default.
• W4380084825 created "2023-06-10" @default.
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• W4380084825 date "2023-07-01" @default.
• W4380084825 modified "2023-09-23" @default.
• W4380084825 title "Controlling Risk Factors Is Always Right" @default.
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• W4380084825 doi "https://doi.org/10.1016/j.amjcard.2023.05.017" @default.
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