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- W4380089895 abstract "Dynamic full-field optical coherence tomography (D-FFOCT) has recently emerged as an invaluable live label-free and non-invasive imaging modality able to image subcellular biological structures and their metabolic activity within complex 3D samples. However, D-FFOCT suffers from fringe artefacts when imaging near reflective surfaces and is highly sensitive to vibrations. Here, we present interface Self-Referenced (iSR) D-FFOCT, an alternative configuration to D-FFOCT that takes advantage of the presence of the sample coverslip in between the sample and the objective by using it as a defocused reference arm, thus avoiding the aforementioned artefacts. We demonstrate the ability of iSR D-FFOCT to image 2D fibroblast cell cultures, which are among the flattest mammalian cells." @default.
- W4380089895 created "2023-06-10" @default.
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- W4380089895 date "2023-06-21" @default.
- W4380089895 modified "2023-10-18" @default.
- W4380089895 title "Interface self-referenced dynamic full-field optical coherence tomography" @default.
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- W4380089895 doi "https://doi.org/10.1364/boe.488663" @default.
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