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- W4380201308 endingPage "102382" @default.
- W4380201308 startingPage "102382" @default.
- W4380201308 abstract "Gonadotropin-releasing hormone (GnRH) neurons are the final output pathway for the brain control of reproduction. The activity of this neuronal population, mainly located at the preoptic area of the hypothalamus, is controlled by a plethora of metabolic signals. However, it has been documented that most of these signal impact on GnRH neurons through indirect neuronal circuits, Kiss1, proopiomelanocortin, and neuropeptide Y/agouti-related peptide neurons being some of the most prominent mediators. In this context, compelling evidence has been gathered in recent years on the role of a large range of neuropeptides and energy sensors in the regulation of GnRH neuronal activity through both direct and indirect mechanisms. The present review summarizes some of the most prominent recent advances in our understanding of the peripheral factors and central mechanisms involved in the metabolic control of GnRH neurons." @default.
- W4380201308 created "2023-06-11" @default.
- W4380201308 creator A5009585563 @default.
- W4380201308 creator A5051664090 @default.
- W4380201308 creator A5060008004 @default.
- W4380201308 creator A5084819904 @default.
- W4380201308 date "2023-08-01" @default.
- W4380201308 modified "2023-09-27" @default.
- W4380201308 title "Central and peripheral mechanisms involved in the control of GnRH neuronal function by metabolic factors" @default.
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