Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380202010> ?p ?o ?g. }
- W4380202010 endingPage "107303" @default.
- W4380202010 startingPage "107303" @default.
- W4380202010 abstract "Background Cough is a troublesome symptom of asthma because it is associated with disease severity and poor asthma control. Bronchial thermoplasty (BT) may be effective in improving cough severity and cough-related quality of life in severe uncontrolled asthma. Objective To evaluate the efficacy of BT for cough in severe uncontrolled asthma. Methods Twelve patients with severe uncontrolled asthma were enrolled in this study between 2018 May and March 2021 and arbitrarily divided into cough-predominant [cough severity Visual Analog Scale (VAS) ≥ 40 mm, n = 8] and typical asthma (cough VAS <40 mm, n = 4) groups. Clinical parameters, such as capsaicin cough sensitivity [C-CS: the concentrations to inhaled capsaicin required to induce at least two (C2) and five (C5) coughs], lung function, and type-2–related biomarkers (fractional nitric oxides and absolute eosinophil counts) and cough-related indices [cough severity VAS and the Leicester Cough Questionnaire (LCQ)] were evaluated before and 3 months after performing BT. Results BT significantly improved both cough-related indices and C-CS in the cough-predominant group. Changes in C-CS were significantly correlated with changes in the LCQ scores (C5: r = 0.65, p = 0.02 for all patients, and r = 0.81, p = 0.01 for the cough-predominant group). Conclusions BT may be effective for cough in severe uncontrolled asthma by improving C-CS. However, further larger cohort studies are necessary to confirm the effect of BT for cough in asthma. Clinical trial registration This study was registered in the UMIN Clinical Trials Registry (Registry ID UMIN: 000031982)." @default.
- W4380202010 created "2023-06-11" @default.
- W4380202010 creator A5004282838 @default.
- W4380202010 creator A5018055530 @default.
- W4380202010 creator A5019508043 @default.
- W4380202010 creator A5019609240 @default.
- W4380202010 creator A5020399033 @default.
- W4380202010 creator A5037639067 @default.
- W4380202010 creator A5039848680 @default.
- W4380202010 creator A5048778164 @default.
- W4380202010 creator A5050972585 @default.
- W4380202010 creator A5052988767 @default.
- W4380202010 creator A5056483654 @default.
- W4380202010 creator A5061931232 @default.
- W4380202010 creator A5062245939 @default.
- W4380202010 creator A5069366555 @default.
- W4380202010 creator A5074171160 @default.
- W4380202010 creator A5079004348 @default.
- W4380202010 date "2023-09-01" @default.
- W4380202010 modified "2023-09-23" @default.
- W4380202010 title "Bronchial thermoplasty improves cough hypersensitivity and cough in severe asthmatics" @default.
- W4380202010 cites W1513929611 @default.
- W4380202010 cites W1780569891 @default.
- W4380202010 cites W1975537294 @default.
- W4380202010 cites W1976550936 @default.
- W4380202010 cites W1988745935 @default.
- W4380202010 cites W1996833509 @default.
- W4380202010 cites W2017933255 @default.
- W4380202010 cites W2022855386 @default.
- W4380202010 cites W2052570127 @default.
- W4380202010 cites W2063707526 @default.
- W4380202010 cites W2076738030 @default.
- W4380202010 cites W2086176435 @default.
- W4380202010 cites W2088814945 @default.
- W4380202010 cites W2098276532 @default.
- W4380202010 cites W2100457204 @default.
- W4380202010 cites W2110258679 @default.
- W4380202010 cites W2114695306 @default.
- W4380202010 cites W2128836390 @default.
- W4380202010 cites W2131303846 @default.
- W4380202010 cites W2151256680 @default.
- W4380202010 cites W2164981395 @default.
- W4380202010 cites W2167856282 @default.
- W4380202010 cites W2293188037 @default.
- W4380202010 cites W2334970314 @default.
- W4380202010 cites W2437690812 @default.
- W4380202010 cites W2507253876 @default.
- W4380202010 cites W2589473004 @default.
- W4380202010 cites W2593467376 @default.
- W4380202010 cites W2755761133 @default.
- W4380202010 cites W2766173624 @default.
- W4380202010 cites W2787537861 @default.
- W4380202010 cites W2790918910 @default.
- W4380202010 cites W2795665222 @default.
- W4380202010 cites W2810183610 @default.
- W4380202010 cites W2889871816 @default.
- W4380202010 cites W2909522739 @default.
- W4380202010 cites W2919179107 @default.
- W4380202010 cites W2924019086 @default.
- W4380202010 cites W2946075834 @default.
- W4380202010 cites W2954937818 @default.
- W4380202010 cites W2956481022 @default.
- W4380202010 cites W3003554406 @default.
- W4380202010 cites W3008838890 @default.
- W4380202010 cites W3045875957 @default.
- W4380202010 cites W3086975334 @default.
- W4380202010 cites W3126352194 @default.
- W4380202010 cites W3131835505 @default.
- W4380202010 cites W3174487394 @default.
- W4380202010 cites W3213362712 @default.
- W4380202010 cites W4207003023 @default.
- W4380202010 cites W4210797603 @default.
- W4380202010 cites W4214937922 @default.
- W4380202010 cites W4282919131 @default.
- W4380202010 cites W4308436328 @default.
- W4380202010 doi "https://doi.org/10.1016/j.rmed.2023.107303" @default.
- W4380202010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37307903" @default.
- W4380202010 hasPublicationYear "2023" @default.
- W4380202010 type Work @default.
- W4380202010 citedByCount "0" @default.
- W4380202010 crossrefType "journal-article" @default.
- W4380202010 hasAuthorship W4380202010A5004282838 @default.
- W4380202010 hasAuthorship W4380202010A5018055530 @default.
- W4380202010 hasAuthorship W4380202010A5019508043 @default.
- W4380202010 hasAuthorship W4380202010A5019609240 @default.
- W4380202010 hasAuthorship W4380202010A5020399033 @default.
- W4380202010 hasAuthorship W4380202010A5037639067 @default.
- W4380202010 hasAuthorship W4380202010A5039848680 @default.
- W4380202010 hasAuthorship W4380202010A5048778164 @default.
- W4380202010 hasAuthorship W4380202010A5050972585 @default.
- W4380202010 hasAuthorship W4380202010A5052988767 @default.
- W4380202010 hasAuthorship W4380202010A5056483654 @default.
- W4380202010 hasAuthorship W4380202010A5061931232 @default.
- W4380202010 hasAuthorship W4380202010A5062245939 @default.
- W4380202010 hasAuthorship W4380202010A5069366555 @default.
- W4380202010 hasAuthorship W4380202010A5074171160 @default.
- W4380202010 hasAuthorship W4380202010A5079004348 @default.
- W4380202010 hasConcept C126322002 @default.