FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380202232> ?p ?o ?g. }

• W4380202232 abstract "Background Disturbed cerebral autoregulation has been reported in children with congenital heart disease before and during cardiopulmonary bypass surgery, but not after. We sought to characterize the cerebral autoregulation status in the early postoperative period in relation to perioperative variables and brain injuries. Methods and Results A prospective and observational study was conducted in 80 patients in the first 48 hours following cardiac surgery. Cerebral oximetry/pressure index (COPI) was retrospectively calculated as a moving linear correlation coefficient between mean arterial blood pressure and cerebral oxygen saturation. Disturbed autoregulation was defined as COPI >0.3. Correlations of COPI with demographic and perioperative variables as well as brain injuries on electroencephalogram and magnetic resonance imaging and early outcomes were analyzed. Thirty-six (45%) patients had periods of abnormal COPI for 7.81 hours (3.38 hours) either at hypotension (median <45 mm Hg) or hypertension (median >90 mm Hg) or both. Overall, COPI became significantly lower over time, suggesting improved autoregulatory status during the 48 postoperative hours. All of the demographic and perioperative variables were significantly associated with COPI, which in turn was associated with the degree of brain injuries and early outcomes. Conclusions Children with congenital heart disease following cardiac surgery often have disturbed autoregulation. Cerebral autoregulation is at least partly the underlying mechanism of brain injury in those children. Careful clinical management to manipulate the related and modifiable factors, particularly arterial blood pressure, may help to maintain adequate cerebral perfusion and reduce brain injury early after cardiopulmonary bypass surgery. Further studies are warranted to determine the significance of impaired cerebral autoregulation in relation to long-term neurodevelopment outcomes." @default.
• W4380202232 created "2023-06-11" @default.
• W4380202232 creator A5015066778 @default.
• W4380202232 creator A5021163747 @default.
• W4380202232 creator A5023364371 @default.
• W4380202232 creator A5029524147 @default.
• W4380202232 creator A5041492302 @default.
• W4380202232 creator A5055937253 @default.
• W4380202232 creator A5057752619 @default.
• W4380202232 creator A5059531929 @default.
• W4380202232 creator A5064204355 @default.
• W4380202232 creator A5065515714 @default.
• W4380202232 creator A5073983362 @default.
• W4380202232 creator A5080488785 @default.
• W4380202232 creator A5080893466 @default.
• W4380202232 creator A5087288464 @default.
• W4380202232 date "2023-06-20" @default.
• W4380202232 modified "2023-09-25" @default.
• W4380202232 title "Cerebral Autoregulation Status in Relation to Brain Injury on Electroencephalogram and Magnetic Resonance Imaging in Children Following Cardiac Surgery" @default.
• W4380202232 cites W1206391664 @default.
• W4380202232 cites W1902838673 @default.
• W4380202232 cites W1967299047 @default.
• W4380202232 cites W1975401574 @default.
• W4380202232 cites W1977425029 @default.
• W4380202232 cites W1992665942 @default.
• W4380202232 cites W1992731636 @default.
• W4380202232 cites W2002214289 @default.
• W4380202232 cites W2011897246 @default.
• W4380202232 cites W2020041770 @default.
• W4380202232 cites W2024313504 @default.
• W4380202232 cites W2042862484 @default.
• W4380202232 cites W2045176203 @default.
• W4380202232 cites W2053971257 @default.
• W4380202232 cites W2061744691 @default.
• W4380202232 cites W2075944017 @default.
• W4380202232 cites W2079492007 @default.
• W4380202232 cites W2088355838 @default.
• W4380202232 cites W2093569692 @default.
• W4380202232 cites W2098495928 @default.
• W4380202232 cites W2120637542 @default.
• W4380202232 cites W2134928333 @default.
• W4380202232 cites W2140627270 @default.
• W4380202232 cites W2141820229 @default.
• W4380202232 cites W2154362597 @default.
• W4380202232 cites W2340455827 @default.
• W4380202232 cites W2619022003 @default.
• W4380202232 cites W2705398737 @default.
• W4380202232 cites W2747633432 @default.
• W4380202232 cites W2894859763 @default.
• W4380202232 cites W2943479233 @default.
• W4380202232 cites W3121468319 @default.
• W4380202232 cites W3144606750 @default.
• W4380202232 cites W3184650415 @default.
• W4380202232 cites W4200083253 @default.
• W4380202232 doi "https://doi.org/10.1161/jaha.122.028147" @default.
• W4380202232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37301753" @default.
• W4380202232 hasPublicationYear "2023" @default.
• W4380202232 type Work @default.
• W4380202232 citedByCount "0" @default.
• W4380202232 crossrefType "journal-article" @default.
• W4380202232 hasAuthorship W4380202232A5015066778 @default.
• W4380202232 hasAuthorship W4380202232A5021163747 @default.
• W4380202232 hasAuthorship W4380202232A5023364371 @default.
• W4380202232 hasAuthorship W4380202232A5029524147 @default.
• W4380202232 hasAuthorship W4380202232A5041492302 @default.
• W4380202232 hasAuthorship W4380202232A5055937253 @default.
• W4380202232 hasAuthorship W4380202232A5057752619 @default.
• W4380202232 hasAuthorship W4380202232A5059531929 @default.
• W4380202232 hasAuthorship W4380202232A5064204355 @default.
• W4380202232 hasAuthorship W4380202232A5065515714 @default.
• W4380202232 hasAuthorship W4380202232A5073983362 @default.
• W4380202232 hasAuthorship W4380202232A5080488785 @default.
• W4380202232 hasAuthorship W4380202232A5080893466 @default.
• W4380202232 hasAuthorship W4380202232A5087288464 @default.
• W4380202232 hasBestOaLocation W43802022321 @default.
• W4380202232 hasConcept C111774379 @default.
• W4380202232 hasConcept C126322002 @default.
• W4380202232 hasConcept C154281038 @default.
• W4380202232 hasConcept C157767197 @default.
• W4380202232 hasConcept C164705383 @default.
• W4380202232 hasConcept C2778789114 @default.
• W4380202232 hasConcept C2778881276 @default.
• W4380202232 hasConcept C31174226 @default.
• W4380202232 hasConcept C42219234 @default.
• W4380202232 hasConcept C555175668 @default.
• W4380202232 hasConcept C71924100 @default.
• W4380202232 hasConcept C84359808 @default.
• W4380202232 hasConcept C84393581 @default.
• W4380202232 hasConceptScore W4380202232C111774379 @default.
• W4380202232 hasConceptScore W4380202232C126322002 @default.
• W4380202232 hasConceptScore W4380202232C154281038 @default.
• W4380202232 hasConceptScore W4380202232C157767197 @default.
• W4380202232 hasConceptScore W4380202232C164705383 @default.
• W4380202232 hasConceptScore W4380202232C2778789114 @default.
• W4380202232 hasConceptScore W4380202232C2778881276 @default.
• W4380202232 hasConceptScore W4380202232C31174226 @default.
• W4380202232 hasConceptScore W4380202232C42219234 @default.
• W4380202232 hasConceptScore W4380202232C555175668 @default.
• W4380202232 hasConceptScore W4380202232C71924100 @default.
• W4380202232 hasConceptScore W4380202232C84359808 @default.

• next