FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380291032> ?p ?o ?g. }

• W4380291032 endingPage "2479" @default.
• W4380291032 startingPage "2472" @default.
• W4380291032 abstract "Background: Microfracture (MF) is frequently performed as a first-line treatment for articular cartilage defects. Although good clinical outcomes are often obtained in the short term, poor clinical outcomes sometimes occur because of subchondral bone deterioration. The condition of the subchondral bone treated with MF may affect the repair of the osteochondral unit. Purpose: To analyze histological findings of the osteochondral unit after performing MF on subchondral bone in different states—normal, absorption, and sclerosis—in a rat model. Study Design: Controlled laboratory study. Methods: Full-thickness cartilage defects (5.0 × 3.0 mm) were created in the weightbearing area of the medial femoral condyle in both knees of 47 Sprague-Dawley rats. Five MF holes were created within the cartilage defect using a 0.55-mm needle to a depth of 1 mm at 0 weeks (normal group), 2 weeks (absorption group), and 4 weeks (sclerosis group) after the cartilage defect was created. In the left knee, MF holes were filled with β-tricalcium phosphate (β-TCP). At 2 and 4 weeks after MF, knee joints were harvested and histologically analyzed. Results: MF holes were enlarged at 2 weeks and further enlarged at 4 weeks in all groups. In the absorption group, osteoclast accumulation around the MF holes and cyst formation were observed. The trabecular bone surrounding the MF holes was thickened in the sclerosis group. The diameter of the MF hole was largest in the absorption group at 2 and 4 weeks after MF compared with the other groups. No subchondral bone cysts were observed after β-TCP implantation. Pineda scores in all groups were significantly better with β-TCP implantation than without β-TCP implantation at 2 and 4 weeks. Conclusion: MF for subchondral bone with bone absorption induced enlargement of the MF holes, cyst formation, and delay of cartilage defect coverage. Implantation of β-TCP into the MF holes enhanced remodeling of the MF holes and improved repair of the osteochondral unit compared with MF only. Therefore, the condition of the subchondral bone treated with MF affects repair of the osteochondral unit in a cartilage defect." @default.
• W4380291032 created "2023-06-13" @default.
• W4380291032 creator A5005203064 @default.
• W4380291032 creator A5019027261 @default.
• W4380291032 creator A5025492054 @default.
• W4380291032 creator A5058184445 @default.
• W4380291032 creator A5086197180 @default.
• W4380291032 date "2023-06-12" @default.
• W4380291032 modified "2023-09-23" @default.
• W4380291032 title "The Subchondral Bone Condition During Microfracture Affects the Repair of the Osteochondral Unit in the Cartilage Defect in the Rat Model" @default.
• W4380291032 cites W1486270218 @default.
• W4380291032 cites W1964744563 @default.
• W4380291032 cites W1968517216 @default.
• W4380291032 cites W1983878023 @default.
• W4380291032 cites W1989524159 @default.
• W4380291032 cites W1996175079 @default.
• W4380291032 cites W1996593219 @default.
• W4380291032 cites W2015832973 @default.
• W4380291032 cites W2022804076 @default.
• W4380291032 cites W2024247198 @default.
• W4380291032 cites W2068529112 @default.
• W4380291032 cites W2071913484 @default.
• W4380291032 cites W2082227862 @default.
• W4380291032 cites W2119763108 @default.
• W4380291032 cites W2121372492 @default.
• W4380291032 cites W2127616408 @default.
• W4380291032 cites W2128447343 @default.
• W4380291032 cites W2129573593 @default.
• W4380291032 cites W2144152716 @default.
• W4380291032 cites W2152072350 @default.
• W4380291032 cites W2163629389 @default.
• W4380291032 cites W2171354897 @default.
• W4380291032 cites W2314036874 @default.
• W4380291032 cites W2317951900 @default.
• W4380291032 cites W2599977362 @default.
• W4380291032 cites W2613784806 @default.
• W4380291032 cites W2761795298 @default.
• W4380291032 cites W2769862774 @default.
• W4380291032 cites W2887322464 @default.
• W4380291032 cites W2888787767 @default.
• W4380291032 cites W3124962483 @default.
• W4380291032 cites W4251818394 @default.
• W4380291032 cites W4288436654 @default.
• W4380291032 cites W4295837929 @default.
• W4380291032 cites W4320857381 @default.
• W4380291032 doi "https://doi.org/10.1177/03635465231177586" @default.
• W4380291032 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37306063" @default.
• W4380291032 hasPublicationYear "2023" @default.
• W4380291032 type Work @default.
• W4380291032 citedByCount "0" @default.
• W4380291032 crossrefType "journal-article" @default.
• W4380291032 hasAuthorship W4380291032A5005203064 @default.
• W4380291032 hasAuthorship W4380291032A5019027261 @default.
• W4380291032 hasAuthorship W4380291032A5025492054 @default.
• W4380291032 hasAuthorship W4380291032A5058184445 @default.
• W4380291032 hasAuthorship W4380291032A5086197180 @default.
• W4380291032 hasConcept C105702510 @default.
• W4380291032 hasConcept C126322002 @default.
• W4380291032 hasConcept C142724271 @default.
• W4380291032 hasConcept C170493617 @default.
• W4380291032 hasConcept C204787440 @default.
• W4380291032 hasConcept C2776033226 @default.
• W4380291032 hasConcept C2776164576 @default.
• W4380291032 hasConcept C2780550940 @default.
• W4380291032 hasConcept C2910895738 @default.
• W4380291032 hasConcept C2989005 @default.
• W4380291032 hasConcept C3018615303 @default.
• W4380291032 hasConcept C3020332539 @default.
• W4380291032 hasConcept C71924100 @default.
• W4380291032 hasConcept C96646087 @default.
• W4380291032 hasConceptScore W4380291032C105702510 @default.
• W4380291032 hasConceptScore W4380291032C126322002 @default.
• W4380291032 hasConceptScore W4380291032C142724271 @default.
• W4380291032 hasConceptScore W4380291032C170493617 @default.
• W4380291032 hasConceptScore W4380291032C204787440 @default.
• W4380291032 hasConceptScore W4380291032C2776033226 @default.
• W4380291032 hasConceptScore W4380291032C2776164576 @default.
• W4380291032 hasConceptScore W4380291032C2780550940 @default.
• W4380291032 hasConceptScore W4380291032C2910895738 @default.
• W4380291032 hasConceptScore W4380291032C2989005 @default.
• W4380291032 hasConceptScore W4380291032C3018615303 @default.
• W4380291032 hasConceptScore W4380291032C3020332539 @default.
• W4380291032 hasConceptScore W4380291032C71924100 @default.
• W4380291032 hasConceptScore W4380291032C96646087 @default.
• W4380291032 hasIssue "9" @default.
• W4380291032 hasLocation W43802910321 @default.
• W4380291032 hasLocation W43802910322 @default.
• W4380291032 hasOpenAccess W4380291032 @default.
• W4380291032 hasPrimaryLocation W43802910321 @default.
• W4380291032 hasRelatedWork W1979639779 @default.
• W4380291032 hasRelatedWork W2032134198 @default.
• W4380291032 hasRelatedWork W2103051602 @default.
• W4380291032 hasRelatedWork W2117631462 @default.
• W4380291032 hasRelatedWork W2133467740 @default.
• W4380291032 hasRelatedWork W2239979296 @default.
• W4380291032 hasRelatedWork W2351825298 @default.
• W4380291032 hasRelatedWork W2393804687 @default.
• W4380291032 hasRelatedWork W3478678 @default.

• next