FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380291217> ?p ?o ?g. }

• W4380291217 endingPage "13708" @default.
• W4380291217 startingPage "13696" @default.
• W4380291217 abstract "The Wood-Ljungdahl Pathway is a unique biological mechanism of carbon dioxide and carbon monoxide fixation proposed to operate through nickel-based organometallic intermediates. The most unusual steps in this metabolic cycle involve a complex of two distinct nickel-iron-sulfur proteins: CO dehydrogenase and acetyl-CoA synthase (CODH/ACS). Here, we describe the nickel-methyl and nickel-acetyl intermediates in ACS completing the characterization of all its proposed organometallic intermediates. A single nickel site (Nip) within the A cluster of ACS undergoes major geometric and redox changes as it transits the planar Nip, tetrahedral Nip-CO and planar Nip-Me and Nip-Ac intermediates. We propose that the Nip intermediates equilibrate among different redox states, driven by an electrochemical-chemical (EC) coupling process, and that geometric changes in the A-cluster linked to large protein conformational changes control entry of CO and the methyl group." @default.
• W4380291217 created "2023-06-13" @default.
• W4380291217 creator A5007771770 @default.
• W4380291217 creator A5020686423 @default.
• W4380291217 creator A5023020011 @default.
• W4380291217 creator A5023744370 @default.
• W4380291217 creator A5034474295 @default.
• W4380291217 creator A5056583971 @default.
• W4380291217 creator A5065284360 @default.
• W4380291217 creator A5080730574 @default.
• W4380291217 creator A5089695755 @default.
• W4380291217 creator A5089995487 @default.
• W4380291217 date "2023-06-12" @default.
• W4380291217 modified "2023-10-16" @default.
• W4380291217 title "Characterization of Methyl- and Acetyl-Ni Intermediates in Acetyl CoA Synthase Formed during Anaerobic CO₂ and CO Fixation" @default.
• W4380291217 cites W1506904792 @default.
• W4380291217 cites W1508069339 @default.
• W4380291217 cites W1510574485 @default.
• W4380291217 cites W1586734181 @default.
• W4380291217 cites W1600883380 @default.
• W4380291217 cites W1602431495 @default.
• W4380291217 cites W1819850013 @default.
• W4380291217 cites W1935623125 @default.
• W4380291217 cites W1964046434 @default.
• W4380291217 cites W1964153297 @default.
• W4380291217 cites W1964154447 @default.
• W4380291217 cites W1967660707 @default.
• W4380291217 cites W1971226138 @default.
• W4380291217 cites W1972489143 @default.
• W4380291217 cites W1983644317 @default.
• W4380291217 cites W1987063718 @default.
• W4380291217 cites W1988091937 @default.
• W4380291217 cites W2015672631 @default.
• W4380291217 cites W2019528254 @default.
• W4380291217 cites W2024843360 @default.
• W4380291217 cites W2035554655 @default.
• W4380291217 cites W2035901147 @default.
• W4380291217 cites W2040243381 @default.
• W4380291217 cites W2040593453 @default.
• W4380291217 cites W2044210528 @default.
• W4380291217 cites W2044620791 @default.
• W4380291217 cites W2047445868 @default.
• W4380291217 cites W2048516944 @default.
• W4380291217 cites W2053490920 @default.
• W4380291217 cites W2057130451 @default.
• W4380291217 cites W2060731855 @default.
• W4380291217 cites W2061939602 @default.
• W4380291217 cites W2069214890 @default.
• W4380291217 cites W2070227796 @default.
• W4380291217 cites W2070563230 @default.
• W4380291217 cites W2071129190 @default.
• W4380291217 cites W2073096890 @default.
• W4380291217 cites W2091540590 @default.
• W4380291217 cites W2103315092 @default.
• W4380291217 cites W2128898932 @default.
• W4380291217 cites W2130336595 @default.
• W4380291217 cites W2148374597 @default.
• W4380291217 cites W2161935361 @default.
• W4380291217 cites W2163663511 @default.
• W4380291217 cites W2164120424 @default.
• W4380291217 cites W2165545400 @default.
• W4380291217 cites W2316693241 @default.
• W4380291217 cites W2322859815 @default.
• W4380291217 cites W2395067586 @default.
• W4380291217 cites W2492146339 @default.
• W4380291217 cites W2506780551 @default.
• W4380291217 cites W2585223025 @default.
• W4380291217 cites W2586409165 @default.
• W4380291217 cites W2587604825 @default.
• W4380291217 cites W2729425227 @default.
• W4380291217 cites W2915492815 @default.
• W4380291217 cites W2960839136 @default.
• W4380291217 cites W3034310241 @default.
• W4380291217 cites W3048609634 @default.
• W4380291217 cites W3048697861 @default.
• W4380291217 cites W3086503530 @default.
• W4380291217 cites W3120254441 @default.
• W4380291217 cites W3187428342 @default.
• W4380291217 cites W3206119355 @default.
• W4380291217 cites W4285726144 @default.
• W4380291217 doi "https://doi.org/10.1021/jacs.3c01772" @default.
• W4380291217 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37306669" @default.
• W4380291217 hasPublicationYear "2023" @default.
• W4380291217 type Work @default.
• W4380291217 citedByCount "0" @default.
• W4380291217 crossrefType "journal-article" @default.
• W4380291217 hasAuthorship W4380291217A5007771770 @default.
• W4380291217 hasAuthorship W4380291217A5020686423 @default.
• W4380291217 hasAuthorship W4380291217A5023020011 @default.
• W4380291217 hasAuthorship W4380291217A5023744370 @default.
• W4380291217 hasAuthorship W4380291217A5034474295 @default.
• W4380291217 hasAuthorship W4380291217A5056583971 @default.
• W4380291217 hasAuthorship W4380291217A5065284360 @default.
• W4380291217 hasAuthorship W4380291217A5080730574 @default.
• W4380291217 hasAuthorship W4380291217A5089695755 @default.
• W4380291217 hasAuthorship W4380291217A5089995487 @default.
• W4380291217 hasBestOaLocation W43802912171 @default.
• W4380291217 hasConcept C112243037 @default.

• next