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- W4380291292 abstract "Abstract Background Human papillomavirus association has changed the landscape of treatment for oropharyngeal squamous cell carcinoma; it remains to be seen whether current post‐treatment surveillance schedules are effective. Objective Evaluate whether post‐treatment surveillance of oropharyngeal cancer through FDG‐PET imaging is modified by human papillomavirus association. Methods A prospective cohort analysis of retrospective data was conducted for patients undergoing treatment of oropharyngeal cancer between 2016 and 2018. This study was conducted at a single large tertiary referral center in Brisbane, Australia. Results Two‐hundred and twenty‐four patients were recruited for the purposes of the study, 193 (86%) with HPV‐associated disease. In this cohort FDG‐PET had a sensitivity of 48.3%, specificity of 72.6%, positive predictive value of 23.7%, and negative predictive value of 88.8% in detecting disease recurrence. Conclusions FDG‐PET in HPV‐associated oropharyngeal cancer has significantly lower positive predictive value when compared to non‐HPV‐associated oropharyngeal cancer. Caution should be used when interpreting positive post‐treatment FDG‐PET." @default.
- W4380291292 created "2023-06-13" @default.
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- W4380291292 date "2023-06-12" @default.
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- W4380291292 title "Post‐treatment <scp>18F‐fludeoxyglocuse‐positron</scp> emission tomography in human papillomavirus‐associated oropharyngeal cancer" @default.
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- W4380291292 doi "https://doi.org/10.1002/hed.27426" @default.
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