Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380291432> ?p ?o ?g. }
- W4380291432 abstract "Artemisia annua L. (Asteraceae Family) is an important plant in Asia that has been used for treating different diseases, including fever due to malaria, wounds, tubercolisis, scabues, pain, convulsions, diabetes, and inflammation. In this study we aimed to evaluate the effects of different polarity extracts (hexane, dichloromethane, ethyl acetate, ethanol, ethanol/water (70 %) and water) from A. annua against the burden of inflammation and oxidative stress occurring in colon tissue exposed to LPS. In parallel, chemical composition, antiradical, and enzyme inhibition effects against α-amylase, α-glucosidase, tyrosinase, and cholinesterases were evaluated. The water extract contained the highest content of the total phenolic with 34.59 mg gallic acid equivalent (GAE)/g extract, while the hexane had the highest content of the total flavonoid (20.06 mg rutin equivalent (RE)/g extract). In antioxidant assays, the polar extracts (ethanol, ethanol/water and water) exhibited stronger radical scavenging and reducing power abilities when compared to non-polar extracts. The hexane extract showed the best AChE, tyrosinase and glucosidase inhibitory effects. All extracts revealed effective anti-inflammatory agents, as demonstrated by the blunting effects on COX-2 and TNFα gene expression. These effects seemed to be not related to the only phenolic content. However, it is worthy of interest to highlight how the higher potency against LPS-induced gene expression was shown by the water extract ; thus suggesting a potential phytotherapy application in the management of clinical symptoms related to inflammatory colon diseases, although future in vivo studies are needed to confirm such in vitro and ex vivo observations." @default.
- W4380291432 created "2023-06-13" @default.
- W4380291432 creator A5003821899 @default.
- W4380291432 creator A5008882202 @default.
- W4380291432 creator A5008895916 @default.
- W4380291432 creator A5018003620 @default.
- W4380291432 creator A5020465694 @default.
- W4380291432 creator A5023388825 @default.
- W4380291432 creator A5024951164 @default.
- W4380291432 creator A5031132046 @default.
- W4380291432 creator A5034792276 @default.
- W4380291432 creator A5046429688 @default.
- W4380291432 creator A5050824577 @default.
- W4380291432 creator A5055336645 @default.
- W4380291432 creator A5065431888 @default.
- W4380291432 creator A5068193682 @default.
- W4380291432 creator A5079470132 @default.
- W4380291432 creator A5083175290 @default.
- W4380291432 creator A5089532880 @default.
- W4380291432 date "2023-07-17" @default.
- W4380291432 modified "2023-09-27" @default.
- W4380291432 title "Chemical Characterization of Different Extracts from <i>Artemisia annua</i> and Their Antioxidant, Enzyme Inhibitory and Anti‐Inflammatory Properties" @default.
- W4380291432 cites W1699617639 @default.
- W4380291432 cites W1750238146 @default.
- W4380291432 cites W1841554146 @default.
- W4380291432 cites W1883029646 @default.
- W4380291432 cites W1969819436 @default.
- W4380291432 cites W1975770902 @default.
- W4380291432 cites W1976919271 @default.
- W4380291432 cites W1981151886 @default.
- W4380291432 cites W1984753812 @default.
- W4380291432 cites W1993590338 @default.
- W4380291432 cites W1997117422 @default.
- W4380291432 cites W1999652235 @default.
- W4380291432 cites W2008108166 @default.
- W4380291432 cites W2013587554 @default.
- W4380291432 cites W2017634218 @default.
- W4380291432 cites W2017811161 @default.
- W4380291432 cites W2020676859 @default.
- W4380291432 cites W2023551843 @default.
- W4380291432 cites W2025667234 @default.
- W4380291432 cites W2028765375 @default.
- W4380291432 cites W2029497930 @default.
- W4380291432 cites W2037572821 @default.
- W4380291432 cites W2043833857 @default.
- W4380291432 cites W2046897841 @default.
- W4380291432 cites W2054276115 @default.
- W4380291432 cites W2060288971 @default.
- W4380291432 cites W2070950181 @default.
- W4380291432 cites W2076857662 @default.
- W4380291432 cites W2076908231 @default.
- W4380291432 cites W2082010159 @default.
- W4380291432 cites W2086184346 @default.
- W4380291432 cites W2091872606 @default.
- W4380291432 cites W2105668062 @default.
- W4380291432 cites W2107277218 @default.
- W4380291432 cites W2121837538 @default.
- W4380291432 cites W2137344325 @default.
- W4380291432 cites W2137736893 @default.
- W4380291432 cites W2142587255 @default.
- W4380291432 cites W2161979413 @default.
- W4380291432 cites W2167682579 @default.
- W4380291432 cites W2172150933 @default.
- W4380291432 cites W2185172372 @default.
- W4380291432 cites W2314402282 @default.
- W4380291432 cites W2340152978 @default.
- W4380291432 cites W2341628457 @default.
- W4380291432 cites W2509818968 @default.
- W4380291432 cites W2511514816 @default.
- W4380291432 cites W2513501240 @default.
- W4380291432 cites W2593725575 @default.
- W4380291432 cites W2610427460 @default.
- W4380291432 cites W2613335053 @default.
- W4380291432 cites W2750571649 @default.
- W4380291432 cites W2774623109 @default.
- W4380291432 cites W2794950260 @default.
- W4380291432 cites W2875881146 @default.
- W4380291432 cites W2896062033 @default.
- W4380291432 cites W2938448257 @default.
- W4380291432 cites W2951446638 @default.
- W4380291432 cites W2952159156 @default.
- W4380291432 cites W2955764702 @default.
- W4380291432 cites W2971755357 @default.
- W4380291432 cites W2995147881 @default.
- W4380291432 cites W2998764138 @default.
- W4380291432 cites W3003765589 @default.
- W4380291432 cites W3008675162 @default.
- W4380291432 cites W3043518867 @default.
- W4380291432 cites W3047552989 @default.
- W4380291432 cites W3096820094 @default.
- W4380291432 cites W3214934314 @default.
- W4380291432 cites W4213205152 @default.
- W4380291432 cites W4214582265 @default.
- W4380291432 cites W4292451743 @default.
- W4380291432 cites W4293715345 @default.
- W4380291432 cites W4295980953 @default.
- W4380291432 cites W4323046287 @default.
- W4380291432 doi "https://doi.org/10.1002/cbdv.202300547" @default.
- W4380291432 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37306942" @default.
- W4380291432 hasPublicationYear "2023" @default.