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• W4380323853 abstract "Abstract Background Pancreatic endocrine insufficiency is more likely to occur after acute pancreatitis (AP), but the risk factors affecting pancreatic endocrine function remain controversial. Therefore, exploring the incidence and risk factors of fasting hyperglycaemia following first-attack AP is important. Methods Data were collected from 311 individuals with first-attack AP without previous diabetes mellitus (DM) or impaired fasting glucose (IFG) history treated in the Renmin Hospital of Wuhan University. Relevant statistical tests were performed. A two-sided p-value < 0.05 was considered statistically significant. Results The incidence of fasting hyperglycaemia in individuals with first-attack AP was 45.3%. Univariate analysis showed that age (χ 2 = 6.27, P = 0.012), aetiology (χ 2 = 11.184, P = 0.004), serum total cholesterol (TC) (χ 2 = 14.622, P < 0.001), and serum triglyceride (TG) (χ 2 = 15.006, P < 0.001) were significantly different between the hyperglycaemia and non-hyperglycaemia groups ( P < 0.05). The serum calcium concentration (Z=-2.480, P = 0.013) was significantly different between the two groups ( P < 0.05). Multiple logistic regression analysis showed that age- ≥60 years ( P < 0.001, OR = 2.631, 95%Cl = 1.529–4.527) and TG ≥ 5.65 mmol/L ( P < 0.001, OR = 3.964, 95%Cl = 1.990–7.895) were independent risk factors for fasting hyperglycaemia in individuals with first-attack AP ( P < 0.05). Conclusions Old age, serum triglycerides, serum total cholesterol, hypocalcaemia, and aetiology are associated with fasting hyperglycaemia following first-attack AP. Age ≥ 60 years and TG ≥ 5.65 mmol/L are independent risk factors for fasting hyperglycaemia following first-attack AP." @default.
• W4380323853 created "2023-06-13" @default.
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• W4380323853 date "2023-06-12" @default.
• W4380323853 modified "2023-10-17" @default.
• W4380323853 title "Incidence and risk factors of fasting hyperglycaemia following first-attack acute pancreatitis before discharge: a retrospective study" @default.
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• W4380323853 doi "https://doi.org/10.1186/s12876-023-02775-7" @default.
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• W4380323853 hasPublicationYear "2023" @default.
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