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• W4380358016 endingPage "101101" @default.
• W4380358016 startingPage "101101" @default.
• W4380358016 abstract "The spiders Psechrus triangulus and Hippasa lycosina are widely distributed in Yunnan Province, China, and are important natural enemies of agricultural pests, yet studies regarding the composition of their venom are lacking. In this study, cDNA libraries were constructed from venom gland tissue of P. triangulus and H. lycosina and used for transcriptomic analysis. From the analysis, 39 and 31 toxin-like sequences were predicted for P. triangulus and H. lycosina, respectively. The predicted neurotoxin sequences were categorized according to cysteine sequence motifs, and the predicted neurotoxin sequences of P. triangulus and H. lycosina could be classified into 9 and 6 toxin families, respectively. In addition, potential acetylcholinesterase, hyaluronidase, and astaxanthin-like metalloproteinases were identified through annotation. In summary, transcriptomic techniques were invaluable in mining the gene expression information from these two spider species to explore the toxin composition of their venom and determine how they differ. Studies of this type provide essential baseline data for studying the evolution and physiological activities of spider toxins and for the potential development of medicinal compounds." @default.
• W4380358016 created "2023-06-13" @default.
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• W4380358016 date "2023-09-01" @default.
• W4380358016 modified "2023-09-23" @default.
• W4380358016 title "Transcriptome-based analyses reveal venom diversity in two araneomorph spiders, Psechrus triangulus and Hippasa lycosina" @default.
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• W4380358016 doi "https://doi.org/10.1016/j.cbd.2023.101101" @default.
• W4380358016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37352672" @default.
• W4380358016 hasPublicationYear "2023" @default.
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