FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380448204> ?p ?o ?g. }

• W4380448204 abstract "Abstract Background and Aims Acute Kidney Injury (AKI) is a syndrome characterized by an abrupt drop in glomerular filtration and/or a decrease in urinary output. The awakening to a different kind of AKI that also occurs outside the hospital named community-acquired AKI (CA-AKI) occurred in 1991, however, few data have been published about its epidemiology, risk factors and outcome, especially in low-income countries. The recognition of risk factors for CA-AKI and development of symptom-based risk tool that aims to predict the risk of AKI might be able to avoid delays in its recognizing, improve the timely diagnosis and patient outcomes in this frequent syndrome. We aimed to assess CA-AKI incidence, characteristics and independent risk factors associated with CA-AKI; to evaluate the discriminatory capacity of a clinical score tool to AKI prediction to predict CA-AKI in our sample. Method We conducted a prospective observational study of general medical admissions to a tertiary hospital in Campinas (São Paulo) between 10th January 2019 and 16th September 2021; we included patients ≥ 14 years, medical suspicion of infection (or confirmed) and /or presence of at least one of the signs or symptoms on admission: fever, dyspnea, decrease in urine output, edema, hypotension, hemodynamic shock, jaundice, petechiae, ecchymosis or decreased level of consciousness. We excluded patients with stage 5 chronic kidney disease at baseline and pre-existing renal replacement therapy (undergoing dialysis and renal transplantation), and also patients with COVID diagnosis. All patients included were assessed utilizing a symptom-based risk score to predict the development of severe AKI, the need for dialysis and mortality. Patients were subjected to complete history taking, socioeconomic and education data were collected. Healthy literacy was assessed using the test of functional health literacy in adults – short version (S- TOFHLA). Predictors of CA-AKI risk were assessed using multivariate logistic regression analysis. Patients were followed up until discharged hospital. The study outcomes were development of CA-AKI, hospital mortality, dialytic need. Results We enrolled 261 patients. CA-AKI was diagnosed in 65 (25%) patients. The CA-AKI patients were older [59 (51-66) vs. 54 (38-65) years, p = 0,02], had higher basal serum creatinine [0,7 (0,5–0,9) vs. 0,6 (0,5-0,8) mg/dL; p = 0,01], lower baseline estimated glomerular filtration rate (eGFR) [103 (88–113) vs. 109 (97–121) mL/min/1,73 m2; p = 0,01] and lower eGFR on admission [64 (44 – 81) vs. 104 (82 – 116) mL/min/1,73 m2; p = 0,0001]. Liver and heart disease were most common comorbidities in the group CA-AKI [10 (16%) vs. 14 (7%) patients, p = 0.04 and 21 (33%) vs. 39 (20%), p = 0,03, respectively]. The risk score did not show significant accuracy to predicting CA-AKI, however, logistic regression showed that scores ≥7 points (OR 95% CI 1.282, 6.133 p = 0.010) followed by age (OR 95% CI 1.007, 1.044 p = 0.008] and liver disease (95% CI 1.063, 6.379 p = 0,036) were independent factors associated with increased risk for CA-AKI in our population. A higher percentage of patients in our sample declared household income &lt; $ 719.73 (month) and the CA-AKI group maintained the same distribution. Only 41 (16%) patients were able to perform the S-TOFHLA and 18 (44%) were considered inadequate or insufficient health literacy. For hospitalized patients, the mean hospital stay in CA-AKI group was longer [8 (4-18) vs. 4 (2-11) days p = 0,001] than without CA-AKI. Overall mortality rate during the follow up was 5% (13 patients), need dialysis 1% (2 patients) and were not statistically significant between the groups. Conclusion Healthy literacy, education, and social class did not show association with CA-AKI; dialysis needed and mortality were not different between the groups CA-AKI or without CA-AKI. Covariates and factors associated with risk for CA-AKI were age, liver disease and scores ≥7 points. The main limitation of our study was not feasible to screen all the patients due to the high numbers seen daily." @default.
• W4380448204 created "2023-06-14" @default.
• W4380448204 creator A5000704932 @default.
• W4380448204 creator A5003303916 @default.
• W4380448204 creator A5010418317 @default.
• W4380448204 creator A5013751501 @default.
• W4380448204 creator A5026317118 @default.
• W4380448204 date "2023-06-01" @default.
• W4380448204 modified "2023-10-03" @default.
• W4380448204 title "#3311 INDEPENDENT PREDICTORS FOR COMMUNITY-ACQUIRED ACUTE KIDNEY INJURY: A PROSPECTIVE COHORT STUDY" @default.
• W4380448204 doi "https://doi.org/10.1093/ndt/gfad063c_3311" @default.
• W4380448204 hasPublicationYear "2023" @default.
• W4380448204 type Work @default.
• W4380448204 citedByCount "0" @default.
• W4380448204 crossrefType "journal-article" @default.
• W4380448204 hasAuthorship W4380448204A5000704932 @default.
• W4380448204 hasAuthorship W4380448204A5003303916 @default.
• W4380448204 hasAuthorship W4380448204A5010418317 @default.
• W4380448204 hasAuthorship W4380448204A5013751501 @default.
• W4380448204 hasAuthorship W4380448204A5026317118 @default.
• W4380448204 hasBestOaLocation W43804482041 @default.
• W4380448204 hasConcept C107130276 @default.
• W4380448204 hasConcept C126322002 @default.
• W4380448204 hasConcept C177713679 @default.
• W4380448204 hasConcept C188816634 @default.
• W4380448204 hasConcept C2776988256 @default.
• W4380448204 hasConcept C2778653478 @default.
• W4380448204 hasConcept C2779978075 @default.
• W4380448204 hasConcept C2780472472 @default.
• W4380448204 hasConcept C2780496750 @default.
• W4380448204 hasConcept C50440223 @default.
• W4380448204 hasConcept C71924100 @default.
• W4380448204 hasConceptScore W4380448204C107130276 @default.
• W4380448204 hasConceptScore W4380448204C126322002 @default.
• W4380448204 hasConceptScore W4380448204C177713679 @default.
• W4380448204 hasConceptScore W4380448204C188816634 @default.
• W4380448204 hasConceptScore W4380448204C2776988256 @default.
• W4380448204 hasConceptScore W4380448204C2778653478 @default.
• W4380448204 hasConceptScore W4380448204C2779978075 @default.
• W4380448204 hasConceptScore W4380448204C2780472472 @default.
• W4380448204 hasConceptScore W4380448204C2780496750 @default.
• W4380448204 hasConceptScore W4380448204C50440223 @default.
• W4380448204 hasConceptScore W4380448204C71924100 @default.
• W4380448204 hasIssue "Supplement_1" @default.
• W4380448204 hasLocation W43804482041 @default.
• W4380448204 hasOpenAccess W4380448204 @default.
• W4380448204 hasPrimaryLocation W43804482041 @default.
• W4380448204 hasRelatedWork W1535100753 @default.
• W4380448204 hasRelatedWork W2004584453 @default.
• W4380448204 hasRelatedWork W2020909032 @default.
• W4380448204 hasRelatedWork W2051032666 @default.
• W4380448204 hasRelatedWork W2060897516 @default.
• W4380448204 hasRelatedWork W2094830370 @default.
• W4380448204 hasRelatedWork W2395590327 @default.
• W4380448204 hasRelatedWork W2411356314 @default.
• W4380448204 hasRelatedWork W4226172547 @default.
• W4380448204 hasRelatedWork W4213383211 @default.
• W4380448204 hasVolume "38" @default.
• W4380448204 isParatext "false" @default.
• W4380448204 isRetracted "false" @default.
• W4380448204 workType "article" @default.