Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380450023> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W4380450023 abstract "Cancer, hematological malignancies and inherited genetic diseases can be diagnosed by detecting chromosome abnormalities. This detection is crucial for the management and follow-up of these diseases. Biologically, there are two categories of chromosome abnormalities: either in their number or in their structure. The process of karyotyping involves creating an ordered representation of the 23 pairs of chromosomes. Each given pair presents a specific band pattern, where both chromosomes are identical, in normal cases. Karyotype images are manually analyzed by qualified cytogeneticists to detect any changes on chromosomes. Based on computer vision methods, it is possible to automate the detection of chromosome abnormalities, which can assist cytogeneticists in the diagnosis process. In the literature, little research has been done to automate the detection of structural abnormalities based on computer vision techniques. In this study, we are interested in the detection of a specific abnormality: the deletion of the long arm of chromosome 5, named del(5q) deletion. We focused our work on the use of the convolutional neural network (CNN) approach, which has shown its ability to provide reliable solutions in computer vision problems. On a collected database, we trained three CNN models to test their ability to differentiate between a healthy and an deleted chromosome 5. The highest performance was provided by VGG19, achieving an accuracy of 98.66%, a sensitivity of 89.33% and specificity of 100%." @default.
- W4380450023 created "2023-06-14" @default.
- W4380450023 creator A5004472410 @default.
- W4380450023 creator A5020685545 @default.
- W4380450023 creator A5035201741 @default.
- W4380450023 creator A5044993894 @default.
- W4380450023 creator A5054711452 @default.
- W4380450023 creator A5055029319 @default.
- W4380450023 date "2023-06-13" @default.
- W4380450023 modified "2023-10-14" @default.
- W4380450023 title "Automatic detection of a structural chromosomal abnormality: the del(5q) deletion" @default.
- W4380450023 doi "https://doi.org/10.1117/12.2665703" @default.
- W4380450023 hasPublicationYear "2023" @default.
- W4380450023 type Work @default.
- W4380450023 citedByCount "0" @default.
- W4380450023 crossrefType "proceedings-article" @default.
- W4380450023 hasAuthorship W4380450023A5004472410 @default.
- W4380450023 hasAuthorship W4380450023A5020685545 @default.
- W4380450023 hasAuthorship W4380450023A5035201741 @default.
- W4380450023 hasAuthorship W4380450023A5044993894 @default.
- W4380450023 hasAuthorship W4380450023A5054711452 @default.
- W4380450023 hasAuthorship W4380450023A5055029319 @default.
- W4380450023 hasConcept C104317684 @default.
- W4380450023 hasConcept C118552586 @default.
- W4380450023 hasConcept C153180895 @default.
- W4380450023 hasConcept C154945302 @default.
- W4380450023 hasConcept C30481170 @default.
- W4380450023 hasConcept C41008148 @default.
- W4380450023 hasConcept C50965678 @default.
- W4380450023 hasConcept C53226629 @default.
- W4380450023 hasConcept C54355233 @default.
- W4380450023 hasConcept C70721500 @default.
- W4380450023 hasConcept C71924100 @default.
- W4380450023 hasConcept C81363708 @default.
- W4380450023 hasConcept C86803240 @default.
- W4380450023 hasConceptScore W4380450023C104317684 @default.
- W4380450023 hasConceptScore W4380450023C118552586 @default.
- W4380450023 hasConceptScore W4380450023C153180895 @default.
- W4380450023 hasConceptScore W4380450023C154945302 @default.
- W4380450023 hasConceptScore W4380450023C30481170 @default.
- W4380450023 hasConceptScore W4380450023C41008148 @default.
- W4380450023 hasConceptScore W4380450023C50965678 @default.
- W4380450023 hasConceptScore W4380450023C53226629 @default.
- W4380450023 hasConceptScore W4380450023C54355233 @default.
- W4380450023 hasConceptScore W4380450023C70721500 @default.
- W4380450023 hasConceptScore W4380450023C71924100 @default.
- W4380450023 hasConceptScore W4380450023C81363708 @default.
- W4380450023 hasConceptScore W4380450023C86803240 @default.
- W4380450023 hasLocation W43804500231 @default.
- W4380450023 hasOpenAccess W4380450023 @default.
- W4380450023 hasPrimaryLocation W43804500231 @default.
- W4380450023 hasRelatedWork W1970446973 @default.
- W4380450023 hasRelatedWork W1990210664 @default.
- W4380450023 hasRelatedWork W2349351051 @default.
- W4380450023 hasRelatedWork W2358175238 @default.
- W4380450023 hasRelatedWork W2369262495 @default.
- W4380450023 hasRelatedWork W2381047706 @default.
- W4380450023 hasRelatedWork W2767651786 @default.
- W4380450023 hasRelatedWork W2912288872 @default.
- W4380450023 hasRelatedWork W3029202981 @default.
- W4380450023 hasRelatedWork W564581980 @default.
- W4380450023 isParatext "false" @default.
- W4380450023 isRetracted "false" @default.
- W4380450023 workType "article" @default.