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- W4380558364 abstract "Background Takayasu’s arteritis (TAK) is a chronic, large-vessel vasculitis that mostly affects young Asian women[1-4]. Vascular inflammation in TAK primarily invades the aorta and its major branches and often leads to arterial stenosis and aneurysms. At present, there is no relevant research report on how to identify the vascular lesions of organs in the early stage and the relationship between the affected vessels. Objectives To investigate the correlation of arterial involvement sites in Takayasu arteritis. Methods We retrospectively investigated data of 144 TAK patients. The clinical and image data of the patients were analyzed. We performed cluster analysis according to the affected artery. Results cluster analysis revealed five clusters of patients. In cluster one was named “abdominal aortic type”. It was characterized by the involvement of arteries in the abdominal aorta, renal artery, coeliac trunk, superior mesenteric artery. In cluster two was named “cardio-cerebral arteries type”. It was characterized by the involvement of arteries in the intracranial artery, coronary artery. In cluster three was named “thoracic aorta type”. It was characterized by the involvement of arteries in the thoracic aorta and pulmonary artery was observed. In cluster four was named “vertebral artery type”. It was characterized by the involvement of arteries in the left vertebral artery, right vertebral artery. In cluster five was named “carotid artery type”. It was characterized by the involvement of arteries in the right common carotid artery, left common carotid artery, right subclavian artery, left subclavian artery, innominate artery. Conclusion Cluster analysis of the involved sites of Takayasu arteritis could be divided into 5 categories. It is abdominal aortic type, cardio-cerebral arteries type, thoracic aorta type, vertebral artery type and carotid artery type. References [1]Arend WP, Michel BA, Bloch DA, Hunder GG, Calabrese LH, Edworthy SM, et al. The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis. Arthritis Rheum. 1990;33(8):1129–34. [2]de Souza AW, de Carvalho JF. Diagnostic and classification criteria of Takayasu arteritis. J Autoimmun. 2014;48-49:79–83. [3]Park SJ, Kim HJ, Park H, Hann HJ, Kim KH, Han S, et al. Incidence, prevalence, mortality and causes of death in Takayasu Arteritis in Korea – A nationwide, population-based study. Int J Cardiol. 2017;235:100–4. [4]Stamatis P. Giant cell arteritis versus Takayasu arteritis: an update. Mediterr J Rheumatol. 2020;31(2):174–82. Acknowledgements: NIL. Disclosure of Interests None Declared." @default.
- W4380558364 created "2023-06-14" @default.
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- W4380558364 date "2023-05-30" @default.
- W4380558364 modified "2023-10-18" @default.
- W4380558364 title "AB0754 CLUSTER ANALYSIS OF ARTERIES INVOLVED IN TAKAYASU ARTERITIS" @default.
- W4380558364 doi "https://doi.org/10.1136/annrheumdis-2023-eular.4518" @default.
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