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- W4380729823 abstract "One new sesquiterpenoid, curcaromatin (1), together with twenty-one known compounds 2-22, were isolated from the rhizomes of Curcuma aromatica Salisb. (Zingiberaceae). Their structures were established by extensive spectroscopic (1D and 2D NMR and HR-MS) analysis. Most of the isolated compounds were investigated for nitric oxide (NO) production in lipopolysaccharide (LPS)-activated RAW264.7 cells. (-)-Xanthorrhizol (3) displayed the strongest NO inhibitory activity with an IC50 value of 4.3 μM, which was 3.7-fold more active than the reference compound, aminoguanidine (IC50 15.9 μM). The selectivity index (SI > 28.1) of compound 3 was almost 3-fold higher than that of aminoguanidine." @default.
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- W4380729823 date "2023-06-15" @default.
- W4380729823 modified "2023-10-16" @default.
- W4380729823 title "Potent nitric oxide inhibitory sesquiterpenoids from the rhizome of <i>Curcuma aromatica</i> Salisb." @default.
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- W4380729823 doi "https://doi.org/10.1080/14786419.2023.2222219" @default.
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