FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380730077> ?p ?o ?g. }

• W4380730077 abstract "Abstract Differences in the correlated activity of networked brain regions have been reported in individuals with generalized anxiety disorder (GAD) but an overreliance on null-hypothesis significance testing (NHST) limits the identification of disorder-relevant relationships. In this preregistered study, we applied both a Bayesian statistical framework and NHST to the analysis of resting-state fMRI scans from females with GAD and matched healthy comparison females. Eleven a-priori hypotheses about functional connectivity (FC) were evaluated using Bayesian (multilevel model) and frequentist ( t -test) inference. Reduced FC between the ventromedial prefrontal cortex (vmPFC) and the posterior-mid insula (PMI) was confirmed by both statistical approaches and was associated with anxiety sensitivity. FC between the vmPFC-anterior insula, the amygdala-PMI, and the amygdala-dorsolateral prefrontal cortex (dlPFC) region pairs did not survive multiple comparison correction using the frequentist approach. However, the Bayesian model provided evidence for these region pairs having decreased FC in the GAD group. Leveraging Bayesian modeling, we demonstrate decreased FC of the vmPFC, insula, amygdala, and dlPFC in females with GAD. Exploiting the Bayesian framework revealed FC abnormalities between region pairs excluded by the frequentist analysis and other previously undescribed regions in GAD, demonstrating the value of applying this approach to resting-state FC data in clinical investigations." @default.
• W4380730077 created "2023-06-16" @default.
• W4380730077 creator A5011557766 @default.
• W4380730077 creator A5026740430 @default.
• W4380730077 creator A5030925693 @default.
• W4380730077 creator A5053885640 @default.
• W4380730077 creator A5057133150 @default.
• W4380730077 creator A5060403232 @default.
• W4380730077 date "2023-06-14" @default.
• W4380730077 modified "2023-10-16" @default.
• W4380730077 title "Reduced vmPFC-insula functional connectivity in generalized anxiety disorder: a Bayesian confirmation study" @default.
• W4380730077 cites W1487460843 @default.
• W4380730077 cites W1513763202 @default.
• W4380730077 cites W1620203002 @default.
• W4380730077 cites W1864952092 @default.
• W4380730077 cites W1895407960 @default.
• W4380730077 cites W1964985504 @default.
• W4380730077 cites W1970818880 @default.
• W4380730077 cites W1973254033 @default.
• W4380730077 cites W1978489779 @default.
• W4380730077 cites W1988850503 @default.
• W4380730077 cites W1989756802 @default.
• W4380730077 cites W2002562224 @default.
• W4380730077 cites W2005244796 @default.
• W4380730077 cites W2008112130 @default.
• W4380730077 cites W2011693288 @default.
• W4380730077 cites W2016521818 @default.
• W4380730077 cites W2026202566 @default.
• W4380730077 cites W2034448215 @default.
• W4380730077 cites W2038671837 @default.
• W4380730077 cites W2040170011 @default.
• W4380730077 cites W2043705607 @default.
• W4380730077 cites W2046557060 @default.
• W4380730077 cites W2054339120 @default.
• W4380730077 cites W2067201491 @default.
• W4380730077 cites W2075803126 @default.
• W4380730077 cites W2085230334 @default.
• W4380730077 cites W2090169446 @default.
• W4380730077 cites W2090495290 @default.
• W4380730077 cites W2095491050 @default.
• W4380730077 cites W2097982135 @default.
• W4380730077 cites W2098423215 @default.
• W4380730077 cites W2106405026 @default.
• W4380730077 cites W2106498117 @default.
• W4380730077 cites W2107790366 @default.
• W4380730077 cites W2108790843 @default.
• W4380730077 cites W2116658855 @default.
• W4380730077 cites W2117140276 @default.
• W4380730077 cites W2121973299 @default.
• W4380730077 cites W2124526585 @default.
• W4380730077 cites W2129624700 @default.
• W4380730077 cites W2132023469 @default.
• W4380730077 cites W2137811349 @default.
• W4380730077 cites W2138092999 @default.
• W4380730077 cites W2144820951 @default.
• W4380730077 cites W2150104440 @default.
• W4380730077 cites W2150258126 @default.
• W4380730077 cites W2151179877 @default.
• W4380730077 cites W2154384688 @default.
• W4380730077 cites W2156874786 @default.
• W4380730077 cites W2162010696 @default.
• W4380730077 cites W2163005465 @default.
• W4380730077 cites W2175149933 @default.
• W4380730077 cites W2293040502 @default.
• W4380730077 cites W2310499978 @default.
• W4380730077 cites W2346625775 @default.
• W4380730077 cites W2402346616 @default.
• W4380730077 cites W2519868887 @default.
• W4380730077 cites W2523729379 @default.
• W4380730077 cites W2547675086 @default.
• W4380730077 cites W2610795206 @default.
• W4380730077 cites W2736579461 @default.
• W4380730077 cites W2736755822 @default.
• W4380730077 cites W2742569683 @default.
• W4380730077 cites W2768172955 @default.
• W4380730077 cites W2777772618 @default.
• W4380730077 cites W2780752719 @default.
• W4380730077 cites W2785114431 @default.
• W4380730077 cites W2792207924 @default.
• W4380730077 cites W2891144030 @default.
• W4380730077 cites W2912015259 @default.
• W4380730077 cites W2951354032 @default.
• W4380730077 cites W2979504717 @default.
• W4380730077 cites W2981605959 @default.
• W4380730077 cites W3006183798 @default.
• W4380730077 cites W3011965540 @default.
• W4380730077 cites W3042526937 @default.
• W4380730077 cites W3049285873 @default.
• W4380730077 cites W3116371286 @default.
• W4380730077 cites W3171418018 @default.
• W4380730077 cites W3203150989 @default.
• W4380730077 cites W4210493812 @default.
• W4380730077 cites W4241074797 @default.
• W4380730077 cites W4246167165 @default.
• W4380730077 cites W4247665917 @default.
• W4380730077 cites W4285504812 @default.
• W4380730077 cites W4320578730 @default.
• W4380730077 cites W634494230 @default.
• W4380730077 doi "https://doi.org/10.1038/s41598-023-35939-2" @default.
• W4380730077 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37316518" @default.

• next