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- W4380792008 abstract "Acute kidney injury is common and deadly, yet the only approved treatment is dialysis. Thus, a better understanding of injury mechanisms and potential therapies is needed. We found that organ-specific, but not extrarenal, extracellular vesicles improved renal function and structure postischemia when given after renal failure occurred. Oxidative stress was decreased and anti-inflammatory interleukin-10 increased with renal, but not skin or platelet, exosomes. We also propose enhanced nascent peptide synthesis as a novel protective mechanism." @default.
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- W4380792008 date "2023-08-01" @default.
- W4380792008 modified "2023-09-27" @default.
- W4380792008 title "Renal, but not platelet or skin, extracellular vesicles decrease oxidative stress, enhance nascent peptide synthesis, and protect from ischemic renal injury" @default.
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- W4380792008 doi "https://doi.org/10.1152/ajprenal.00321.2022" @default.
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