Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380854536> ?p ?o ?g. }
- W4380854536 endingPage "154614" @default.
- W4380854536 startingPage "154614" @default.
- W4380854536 abstract "Pancreatic ductal adenocarcinoma (PDAC) is a cancer that is usually diagnosed at late stages. This highly aggressive tumor is resistant to most therapeutic approaches, necessitating identification of differentially expressed genes to design new therapies. Herein, we have analyzed single cell RNA-seq data with a systems biology approach to identify important differentially expressed genes in PDAC samples compared to adjacent non-cancerous samples. Our approach revealed 1462 DEmRNAs, including 1389 downregulated DEmRNAs (like PRSS1 and CLPS) and 73 upregulated DEmRNAs (like HSPA1A and SOCS3), 27 DElncRNAs, including 26 downregulated DElncRNAs (like LINC00472 and SNHG7) and 1 upregulated DElncRNA (SNHG5). We also listed a number of dysregulated signaling pathways, abnormally expressed genes and aberrant cellular functions in PDAC which can be used as possible biomarkers and therapeutic targets in this type of cancer." @default.
- W4380854536 created "2023-06-16" @default.
- W4380854536 creator A5032297413 @default.
- W4380854536 creator A5036114929 @default.
- W4380854536 creator A5055061626 @default.
- W4380854536 creator A5073796304 @default.
- W4380854536 creator A5083975126 @default.
- W4380854536 creator A5086371778 @default.
- W4380854536 date "2023-08-01" @default.
- W4380854536 modified "2023-10-16" @default.
- W4380854536 title "Single cell RNA-seq analysis with a systems biology approach to recognize important differentially expressed genes in pancreatic ductal adenocarcinoma compared to adjacent non-cancerous samples by targeting pancreatic endothelial cells" @default.
- W4380854536 cites W1981509058 @default.
- W4380854536 cites W1981940137 @default.
- W4380854536 cites W1987313243 @default.
- W4380854536 cites W2010168796 @default.
- W4380854536 cites W2093859254 @default.
- W4380854536 cites W2096173332 @default.
- W4380854536 cites W2103151642 @default.
- W4380854536 cites W2103912979 @default.
- W4380854536 cites W2133559011 @default.
- W4380854536 cites W2134629862 @default.
- W4380854536 cites W2141224543 @default.
- W4380854536 cites W2159675211 @default.
- W4380854536 cites W2162036268 @default.
- W4380854536 cites W2168645747 @default.
- W4380854536 cites W2179438025 @default.
- W4380854536 cites W2179886188 @default.
- W4380854536 cites W2340761255 @default.
- W4380854536 cites W2560101007 @default.
- W4380854536 cites W2597447845 @default.
- W4380854536 cites W2736730167 @default.
- W4380854536 cites W2758815122 @default.
- W4380854536 cites W2897825874 @default.
- W4380854536 cites W2899587820 @default.
- W4380854536 cites W2907514116 @default.
- W4380854536 cites W2911657438 @default.
- W4380854536 cites W2954902957 @default.
- W4380854536 cites W2970358232 @default.
- W4380854536 cites W2972661346 @default.
- W4380854536 cites W3096568637 @default.
- W4380854536 cites W3164692211 @default.
- W4380854536 cites W3180777398 @default.
- W4380854536 cites W3210631970 @default.
- W4380854536 cites W3212581192 @default.
- W4380854536 cites W4214900502 @default.
- W4380854536 cites W4294216483 @default.
- W4380854536 cites W4296993022 @default.
- W4380854536 doi "https://doi.org/10.1016/j.prp.2023.154614" @default.
- W4380854536 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37329816" @default.
- W4380854536 hasPublicationYear "2023" @default.
- W4380854536 type Work @default.
- W4380854536 citedByCount "0" @default.
- W4380854536 crossrefType "journal-article" @default.
- W4380854536 hasAuthorship W4380854536A5032297413 @default.
- W4380854536 hasAuthorship W4380854536A5036114929 @default.
- W4380854536 hasAuthorship W4380854536A5055061626 @default.
- W4380854536 hasAuthorship W4380854536A5073796304 @default.
- W4380854536 hasAuthorship W4380854536A5083975126 @default.
- W4380854536 hasAuthorship W4380854536A5086371778 @default.
- W4380854536 hasBestOaLocation W43808545361 @default.
- W4380854536 hasConcept C104317684 @default.
- W4380854536 hasConcept C107397762 @default.
- W4380854536 hasConcept C121608353 @default.
- W4380854536 hasConcept C127561419 @default.
- W4380854536 hasConcept C150194340 @default.
- W4380854536 hasConcept C162317418 @default.
- W4380854536 hasConcept C2780210213 @default.
- W4380854536 hasConcept C2781182431 @default.
- W4380854536 hasConcept C2992026798 @default.
- W4380854536 hasConcept C502942594 @default.
- W4380854536 hasConcept C54355233 @default.
- W4380854536 hasConcept C60644358 @default.
- W4380854536 hasConcept C67705224 @default.
- W4380854536 hasConcept C70721500 @default.
- W4380854536 hasConcept C86803240 @default.
- W4380854536 hasConceptScore W4380854536C104317684 @default.
- W4380854536 hasConceptScore W4380854536C107397762 @default.
- W4380854536 hasConceptScore W4380854536C121608353 @default.
- W4380854536 hasConceptScore W4380854536C127561419 @default.
- W4380854536 hasConceptScore W4380854536C150194340 @default.
- W4380854536 hasConceptScore W4380854536C162317418 @default.
- W4380854536 hasConceptScore W4380854536C2780210213 @default.
- W4380854536 hasConceptScore W4380854536C2781182431 @default.
- W4380854536 hasConceptScore W4380854536C2992026798 @default.
- W4380854536 hasConceptScore W4380854536C502942594 @default.
- W4380854536 hasConceptScore W4380854536C54355233 @default.
- W4380854536 hasConceptScore W4380854536C60644358 @default.
- W4380854536 hasConceptScore W4380854536C67705224 @default.
- W4380854536 hasConceptScore W4380854536C70721500 @default.
- W4380854536 hasConceptScore W4380854536C86803240 @default.
- W4380854536 hasLocation W43808545361 @default.
- W4380854536 hasLocation W43808545362 @default.
- W4380854536 hasOpenAccess W4380854536 @default.
- W4380854536 hasPrimaryLocation W43808545361 @default.
- W4380854536 hasRelatedWork W1981509058 @default.
- W4380854536 hasRelatedWork W2009966535 @default.
- W4380854536 hasRelatedWork W2043890160 @default.
- W4380854536 hasRelatedWork W2073555182 @default.