FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380872743> ?p ?o ?g. }

• W4380872743 endingPage "12593" @default.
• W4380872743 startingPage "12573" @default.
• W4380872743 abstract "Recombinant granulocyte colony-stimulating factor (G-CSF), with a direct repair effect on injured cardiomyocytes against myocardial infarction ischemia-reperfusion-injury (IRI), displays a poor effect owing to the limited cardiac targeting efficacy. There are almost no reports of nanomaterials that deliver G-CSF to the IRI site. Herein, we propose a way to protect G-CSF by constructing one layer of nitric oxide (NO)/hydrogen sulfide (H2S) nanomotors on its outside. NO/H2S nanomotors with specific chemotactic ability to high expression of reactive oxygen species (ROS)/induced nitric oxide synthase (iNOS) at the IRI site can deliver G-CSF to the IRI site efficiently. Meanwhile, superoxide dismutase is covalently bound to the outermost part, reducing ROS at the IRI site through a cascade effect with NO/H2S nanomotors. The synergistic effect between NO and H2S on the effective regulation of the IRI microenvironment can not only avoid toxicity caused by excessive concentration of a single gas but also reduce inflammation level and relieve calcium overload, so as to promote G-CSF to play a cardioprotective role." @default.
• W4380872743 created "2023-06-17" @default.
• W4380872743 creator A5014709585 @default.
• W4380872743 creator A5015105154 @default.
• W4380872743 creator A5020841779 @default.
• W4380872743 creator A5030887101 @default.
• W4380872743 creator A5037039319 @default.
• W4380872743 creator A5053067736 @default.
• W4380872743 creator A5062402725 @default.
• W4380872743 creator A5072078815 @default.
• W4380872743 creator A5073501391 @default.
• W4380872743 creator A5081377631 @default.
• W4380872743 creator A5082429319 @default.
• W4380872743 creator A5083584513 @default.
• W4380872743 creator A5083670525 @default.
• W4380872743 creator A5085929473 @default.
• W4380872743 creator A5091261631 @default.
• W4380872743 date "2023-06-16" @default.
• W4380872743 modified "2023-10-17" @default.
• W4380872743 title "Chemotactic NO/H₂S Nanomotors Realizing Cardiac Targeting of G-CSF against Myocardial Ischemia-Reperfusion Injury" @default.
• W4380872743 cites W1585390661 @default.
• W4380872743 cites W1892519879 @default.
• W4380872743 cites W1966228028 @default.
• W4380872743 cites W1980458823 @default.
• W4380872743 cites W1991379056 @default.
• W4380872743 cites W2005880799 @default.
• W4380872743 cites W2007554420 @default.
• W4380872743 cites W2011847172 @default.
• W4380872743 cites W2012676660 @default.
• W4380872743 cites W2018076136 @default.
• W4380872743 cites W2020647888 @default.
• W4380872743 cites W2022422715 @default.
• W4380872743 cites W2028606217 @default.
• W4380872743 cites W2030710974 @default.
• W4380872743 cites W2047563687 @default.
• W4380872743 cites W2050744280 @default.
• W4380872743 cites W2051395985 @default.
• W4380872743 cites W2051876980 @default.
• W4380872743 cites W2057646089 @default.
• W4380872743 cites W2058851462 @default.
• W4380872743 cites W2067949828 @default.
• W4380872743 cites W2069229543 @default.
• W4380872743 cites W2069943302 @default.
• W4380872743 cites W2072017110 @default.
• W4380872743 cites W2077388370 @default.
• W4380872743 cites W2092941517 @default.
• W4380872743 cites W2093604853 @default.
• W4380872743 cites W2102085357 @default.
• W4380872743 cites W2105457815 @default.
• W4380872743 cites W2116530052 @default.
• W4380872743 cites W2116999983 @default.
• W4380872743 cites W2123970227 @default.
• W4380872743 cites W2126876006 @default.
• W4380872743 cites W2148913109 @default.
• W4380872743 cites W2152247516 @default.
• W4380872743 cites W2159254137 @default.
• W4380872743 cites W2164009656 @default.
• W4380872743 cites W2165201727 @default.
• W4380872743 cites W2201917454 @default.
• W4380872743 cites W2239083587 @default.
• W4380872743 cites W2332595677 @default.
• W4380872743 cites W2591053022 @default.
• W4380872743 cites W259232106 @default.
• W4380872743 cites W2750214174 @default.
• W4380872743 cites W2777035259 @default.
• W4380872743 cites W2780151280 @default.
• W4380872743 cites W2799529459 @default.
• W4380872743 cites W2800356932 @default.
• W4380872743 cites W2801172894 @default.
• W4380872743 cites W2803132938 @default.
• W4380872743 cites W2902104113 @default.
• W4380872743 cites W2908439034 @default.
• W4380872743 cites W2921979876 @default.
• W4380872743 cites W2928131335 @default.
• W4380872743 cites W2955781995 @default.
• W4380872743 cites W2975365532 @default.
• W4380872743 cites W2981524920 @default.
• W4380872743 cites W2989952171 @default.
• W4380872743 cites W2997521288 @default.
• W4380872743 cites W3002371404 @default.
• W4380872743 cites W3034236107 @default.
• W4380872743 cites W3038341522 @default.
• W4380872743 cites W3045740151 @default.
• W4380872743 cites W3094125068 @default.
• W4380872743 cites W3095974721 @default.
• W4380872743 cites W3124265836 @default.
• W4380872743 cites W3148731423 @default.
• W4380872743 cites W3169523536 @default.
• W4380872743 cites W3176618862 @default.
• W4380872743 cites W3181635687 @default.
• W4380872743 cites W3186594920 @default.
• W4380872743 cites W3211617431 @default.
• W4380872743 cites W3213673096 @default.
• W4380872743 cites W4211143906 @default.
• W4380872743 cites W4246057271 @default.
• W4380872743 cites W4281635696 @default.
• W4380872743 cites W4291036658 @default.
• W4380872743 cites W4296345257 @default.

• next