FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380996817> ?p ?o ?g. }

• W4380996817 endingPage "4615" @default.
• W4380996817 startingPage "4609" @default.
• W4380996817 abstract "The recent SARS-Cov2 pandemic and mpox health emergency have led to renewed interest in intradermal vaccination due to its dose sparing potential. Indeed, intradermal vaccination is particularly of interest for use in mass vaccination campaigns, pandemic preparedness programs, and/or for vaccines that are expensive or in short supply. Moreover, the rich immune network in the skin makes it an attractive target not only for prophylactic vaccination, but also for therapeutic vaccination, like immunotherapy and (dendritic) cell-based therapies. The aim of the current paper was to provide an overview of preclinical data generated with VAX-ID®, a novel intradermal drug delivery device, to allow assessing it performance, safety and usability. The device can overcome challenges seen with the Mantoux technique whereby the needle needs to be inserted under a shallow angle. Various parameters of VAX-ID® were evaluated, including dead-space volume, dose accuracy, penetration depth & liquid deposit in piglets, as well as usability by healthcare professionals. The device has shown to have a low dead volume and a high dose accuracy. Importantly, the device performed successful injections at a predefined depth into the dermis with a high safety profile as confirmed by visual and histological evaluation in piglets. Moreover, the device was rated as easy to use by healthcare professionals. The combined preclinical performance and usability findings indicate that VAX-ID® can provide reliable, standardized and accurate drug delivery in the dermal layer of the skin with a high ease of use. The device offers a solution for injection of various prophylactic as well as therapeutic vaccines." @default.
• W4380996817 created "2023-06-17" @default.
• W4380996817 creator A5064576086 @default.
• W4380996817 creator A5068643172 @default.
• W4380996817 creator A5075483017 @default.
• W4380996817 creator A5090450653 @default.
• W4380996817 creator A5092190142 @default.
• W4380996817 creator A5092190143 @default.
• W4380996817 date "2023-07-01" @default.
• W4380996817 modified "2023-09-26" @default.
• W4380996817 title "Preclinical evaluation of performance, safety and usability of VAX-ID®, a novel intradermal injection device" @default.
• W4380996817 cites W1527892029 @default.
• W4380996817 cites W1884070799 @default.
• W4380996817 cites W1992234727 @default.
• W4380996817 cites W1992894246 @default.
• W4380996817 cites W2001663048 @default.
• W4380996817 cites W2014002941 @default.
• W4380996817 cites W2034807093 @default.
• W4380996817 cites W2039009483 @default.
• W4380996817 cites W2045138888 @default.
• W4380996817 cites W2052338984 @default.
• W4380996817 cites W2066442197 @default.
• W4380996817 cites W2082436249 @default.
• W4380996817 cites W2091447598 @default.
• W4380996817 cites W2112080359 @default.
• W4380996817 cites W2162845988 @default.
• W4380996817 cites W2164707561 @default.
• W4380996817 cites W2506030309 @default.
• W4380996817 cites W2587090632 @default.
• W4380996817 cites W2801093090 @default.
• W4380996817 cites W2905902275 @default.
• W4380996817 cites W2918495884 @default.
• W4380996817 cites W2942901252 @default.
• W4380996817 cites W2945450369 @default.
• W4380996817 cites W2953452049 @default.
• W4380996817 cites W3015033438 @default.
• W4380996817 cites W3122946735 @default.
• W4380996817 cites W3129297995 @default.
• W4380996817 cites W3181844424 @default.
• W4380996817 cites W4307227094 @default.
• W4380996817 doi "https://doi.org/10.1016/j.vaccine.2023.06.028" @default.
• W4380996817 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37330370" @default.
• W4380996817 hasPublicationYear "2023" @default.
• W4380996817 type Work @default.
• W4380996817 citedByCount "0" @default.
• W4380996817 crossrefType "journal-article" @default.
• W4380996817 hasAuthorship W4380996817A5064576086 @default.
• W4380996817 hasAuthorship W4380996817A5068643172 @default.
• W4380996817 hasAuthorship W4380996817A5075483017 @default.
• W4380996817 hasAuthorship W4380996817A5090450653 @default.
• W4380996817 hasAuthorship W4380996817A5092190142 @default.
• W4380996817 hasAuthorship W4380996817A5092190143 @default.
• W4380996817 hasBestOaLocation W43809968171 @default.
• W4380996817 hasConcept C107457646 @default.
• W4380996817 hasConcept C136229726 @default.
• W4380996817 hasConcept C160735492 @default.
• W4380996817 hasConcept C162324750 @default.
• W4380996817 hasConcept C170130773 @default.
• W4380996817 hasConcept C19527891 @default.
• W4380996817 hasConcept C203014093 @default.
• W4380996817 hasConcept C22070199 @default.
• W4380996817 hasConcept C41008148 @default.
• W4380996817 hasConcept C50522688 @default.
• W4380996817 hasConcept C71924100 @default.
• W4380996817 hasConceptScore W4380996817C107457646 @default.
• W4380996817 hasConceptScore W4380996817C136229726 @default.
• W4380996817 hasConceptScore W4380996817C160735492 @default.
• W4380996817 hasConceptScore W4380996817C162324750 @default.
• W4380996817 hasConceptScore W4380996817C170130773 @default.
• W4380996817 hasConceptScore W4380996817C19527891 @default.
• W4380996817 hasConceptScore W4380996817C203014093 @default.
• W4380996817 hasConceptScore W4380996817C22070199 @default.
• W4380996817 hasConceptScore W4380996817C41008148 @default.
• W4380996817 hasConceptScore W4380996817C50522688 @default.
• W4380996817 hasConceptScore W4380996817C71924100 @default.
• W4380996817 hasIssue "31" @default.
• W4380996817 hasLocation W43809968171 @default.
• W4380996817 hasLocation W43809968172 @default.
• W4380996817 hasLocation W43809968173 @default.
• W4380996817 hasOpenAccess W4380996817 @default.
• W4380996817 hasPrimaryLocation W43809968171 @default.
• W4380996817 hasRelatedWork W2077735502 @default.
• W4380996817 hasRelatedWork W2098941602 @default.
• W4380996817 hasRelatedWork W2163615598 @default.
• W4380996817 hasRelatedWork W2300139772 @default.
• W4380996817 hasRelatedWork W2572081132 @default.
• W4380996817 hasRelatedWork W2790236813 @default.
• W4380996817 hasRelatedWork W3146107739 @default.
• W4380996817 hasRelatedWork W4205354303 @default.
• W4380996817 hasRelatedWork W4282018554 @default.
• W4380996817 hasRelatedWork W4366405007 @default.
• W4380996817 hasVolume "41" @default.
• W4380996817 isParatext "false" @default.
• W4380996817 isRetracted "false" @default.
• W4380996817 workType "article" @default.