Matches in SemOpenAlex for { <https://semopenalex.org/work/W4380997910> ?p ?o ?g. }
- W4380997910 abstract "Cirrhosis transcends various progressive stages from compensation to decompensation driven by the severity of portal hypertension. The downstream effect of increasing portal hypertension severity leads to various pathophysiological pathways, which result in the cardinal complications of cirrhosis, including ascites, variceal hemorrhage, and hepatic encephalopathy. Additionally, the severity of portal hypertension is the central driver for further advanced complications of hyperdynamic circulation, hepatorenal syndrome, and cirrhotic cardiomyopathy. The management of these individual complications has specific nuances which have undergone significant developments. In contrast to the classical natural history of cirrhosis and its complications which follows an insidious trajectory, acute-on-chronic failure (ACLF) leads to a rapidly downhill course with high short-term mortality unless intervened at the early stages. The management of ACLF involves specific interventions, which have quickly evolved in recent years. In this review, we focus on complications of portal hypertension and delve into an approach toward ACLF." @default.
- W4380997910 created "2023-06-17" @default.
- W4380997910 creator A5013471768 @default.
- W4380997910 creator A5025871358 @default.
- W4380997910 creator A5030804963 @default.
- W4380997910 creator A5032351621 @default.
- W4380997910 creator A5037076474 @default.
- W4380997910 creator A5055799027 @default.
- W4380997910 creator A5062210742 @default.
- W4380997910 creator A5065083439 @default.
- W4380997910 date "2023-06-15" @default.
- W4380997910 modified "2023-09-26" @default.
- W4380997910 title "Pathophysiology and management of liver cirrhosis: from portal hypertension to acute-on-chronic liver failure" @default.
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