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- W4380997918 endingPage "1265" @default.
- W4380997918 startingPage "1265" @default.
- W4380997918 abstract "Sudden cardiac death (SCD) is an unexpected natural death due to cardiac causes, usually happening within one hour of symptom manifestation or in individuals in good health up to 24 h before the event. Genomic screening has been increasingly applied as a useful approach to detecting the genetic variants that potentially contribute to SCD and helping the evaluation of SCD cases in the post-mortem setting. Our aim was to identify the genetic markers associated with SCD, which might enable its target screening and prevention. In this scope, a case-control analysis through the post-mortem genome-wide screening of 30 autopsy cases was performed. We identified a high number of novel genetic variants associated with SCD, of which 25 polymorphisms were consistent with a previous link to cardiovascular diseases. We ascertained that many genes have been already linked to cardiovascular system functioning and diseases and that the metabolisms most implicated in SCD are the lipid, cholesterol, arachidonic acid, and drug metabolisms, suggesting their roles as potential risk factors. Overall, the genetic variants pinpointed herein might be useful markers of SCD, but the novelty of these results requires further investigations." @default.
- W4380997918 created "2023-06-17" @default.
- W4380997918 creator A5012406384 @default.
- W4380997918 creator A5019564857 @default.
- W4380997918 creator A5040152187 @default.
- W4380997918 creator A5047470048 @default.
- W4380997918 creator A5051701684 @default.
- W4380997918 creator A5064438405 @default.
- W4380997918 creator A5080134092 @default.
- W4380997918 date "2023-06-15" @default.
- W4380997918 modified "2023-09-30" @default.
- W4380997918 title "A Genome-Wide Analysis of a Sudden Cardiac Death Cohort: Identifying Novel Target Variants in the Era of Molecular Autopsy" @default.
- W4380997918 cites W1200359578 @default.
- W4380997918 cites W1495302629 @default.
- W4380997918 cites W1507452774 @default.
- W4380997918 cites W1836340926 @default.
- W4380997918 cites W1854770504 @default.
- W4380997918 cites W1875102167 @default.
- W4380997918 cites W1974882211 @default.
- W4380997918 cites W2000993996 @default.
- W4380997918 cites W2006059705 @default.
- W4380997918 cites W2019386739 @default.
- W4380997918 cites W2044986828 @default.
- W4380997918 cites W2049767963 @default.
- W4380997918 cites W2051150244 @default.
- W4380997918 cites W2053893399 @default.
- W4380997918 cites W2067684528 @default.
- W4380997918 cites W2070050178 @default.
- W4380997918 cites W2074629566 @default.
- W4380997918 cites W2081783279 @default.
- W4380997918 cites W2102426258 @default.
- W4380997918 cites W2104549677 @default.
- W4380997918 cites W2108169091 @default.
- W4380997918 cites W2116533376 @default.
- W4380997918 cites W2116678763 @default.
- W4380997918 cites W2121795854 @default.
- W4380997918 cites W2123446926 @default.
- W4380997918 cites W2125027040 @default.
- W4380997918 cites W2131197556 @default.
- W4380997918 cites W2132603512 @default.
- W4380997918 cites W2134335725 @default.
- W4380997918 cites W2142548787 @default.
- W4380997918 cites W2142769596 @default.
- W4380997918 cites W2144043342 @default.
- W4380997918 cites W2146962564 @default.
- W4380997918 cites W2149131025 @default.
- W4380997918 cites W2157752701 @default.
- W4380997918 cites W2161633633 @default.
- W4380997918 cites W2169076729 @default.
- W4380997918 cites W2169804223 @default.
- W4380997918 cites W2416382276 @default.
- W4380997918 cites W2474247475 @default.
- W4380997918 cites W2491820136 @default.
- W4380997918 cites W2514295222 @default.
- W4380997918 cites W2519483107 @default.
- W4380997918 cites W2593007762 @default.
- W4380997918 cites W2737005305 @default.
- W4380997918 cites W2750874115 @default.
- W4380997918 cites W2754857326 @default.
- W4380997918 cites W2786222183 @default.
- W4380997918 cites W2788198493 @default.
- W4380997918 cites W2790653691 @default.
- W4380997918 cites W2794127771 @default.
- W4380997918 cites W2893054388 @default.
- W4380997918 cites W2914613198 @default.
- W4380997918 cites W2917025828 @default.
- W4380997918 cites W2952686929 @default.
- W4380997918 cites W2961333572 @default.
- W4380997918 cites W2962769165 @default.
- W4380997918 cites W2977263104 @default.
- W4380997918 cites W2989051567 @default.
- W4380997918 cites W3001525407 @default.
- W4380997918 cites W3008488491 @default.
- W4380997918 cites W3011413344 @default.
- W4380997918 cites W3012570809 @default.
- W4380997918 cites W3013027981 @default.
- W4380997918 cites W3017203576 @default.
- W4380997918 cites W3044870380 @default.
- W4380997918 cites W3045517404 @default.
- W4380997918 cites W3087191797 @default.
- W4380997918 cites W3112948680 @default.
- W4380997918 cites W3113925949 @default.
- W4380997918 cites W3128540265 @default.
- W4380997918 cites W3134222661 @default.
- W4380997918 cites W3159679214 @default.
- W4380997918 cites W3191468617 @default.
- W4380997918 cites W3213406154 @default.
- W4380997918 cites W39432941 @default.
- W4380997918 cites W4200185762 @default.
- W4380997918 cites W4206955857 @default.
- W4380997918 cites W4210682818 @default.
- W4380997918 cites W4211244839 @default.
- W4380997918 cites W4214880185 @default.
- W4380997918 cites W4220682024 @default.
- W4380997918 cites W4318457346 @default.
- W4380997918 cites W4321377703 @default.
- W4380997918 cites W4321793918 @default.
- W4380997918 doi "https://doi.org/10.3390/genes14061265" @default.