FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381051334> ?p ?o ?g. }

• W4381051334 endingPage "102145" @default.
• W4381051334 startingPage "102145" @default.
• W4381051334 abstract "Mongolian medicine prescriptions are recognized as promising gastroprotective agents. This study is to explore the effects and mechanisms of Liuwei Anxiao San (LAS) in gastric ulcer (GU). GU rat models were established using acetic acid, followed by treatment with LAS at different doses and/or the JAK2 agonist Coumermycin A1 (CA1). The ulcerous area and inhibition rates were calculated. The mucosal damage and cell apoptosis in gastric tissues were assessed by H&E and TUNEL staining. The activities of SOD, GSH-Px, and CAT, and MDA levels were measured. The levels of pro-inflammatory and anti-inflammatory factors were determined by ELISA. The activation of the JAK2/STAT3 pathway was determined by Western blot. As the results suggested, LAS dose-dependently ameliorated gastric mucosal damage and inhibited oxidative stress and inflammatory response, evidenced by increased activities of SOD, GSH-Px, and CAT, decreased MDA level, increment of anti-inflammatory factors and decrement of pro-inflammatory factors, and inhibited the activation of the JAK2/STAT3 pathway in GU rats. CA1 partly abolished the function of LAS on gastric mucosal injury, oxidative stress, and inflammation in GU rats. In conclusion, LAS protects against gastric mucosal injury in GU rats through inhibition of oxidative stress and inflammation by suppressing the JAK2/STAT3 pathway." @default.
• W4381051334 created "2023-06-18" @default.
• W4381051334 creator A5021293751 @default.
• W4381051334 creator A5023384331 @default.
• W4381051334 creator A5030719170 @default.
• W4381051334 creator A5062522582 @default.
• W4381051334 date "2023-08-01" @default.
• W4381051334 modified "2023-09-27" @default.
• W4381051334 title "Liuwei Anxiao San protects gastric mucosa from gastric ulcer in rats by regulating the JAK2/STAT3 pathway" @default.
• W4381051334 cites W1974477809 @default.
• W4381051334 cites W1980270902 @default.
• W4381051334 cites W2030090764 @default.
• W4381051334 cites W2342725433 @default.
• W4381051334 cites W2400434829 @default.
• W4381051334 cites W2549402080 @default.
• W4381051334 cites W2807087421 @default.
• W4381051334 cites W2899491725 @default.
• W4381051334 cites W2908381102 @default.
• W4381051334 cites W2911555809 @default.
• W4381051334 cites W2978896835 @default.
• W4381051334 cites W2979539797 @default.
• W4381051334 cites W2991085179 @default.
• W4381051334 cites W2993438310 @default.
• W4381051334 cites W2997330204 @default.
• W4381051334 cites W3001733563 @default.
• W4381051334 cites W3002119860 @default.
• W4381051334 cites W3028449605 @default.
• W4381051334 cites W3040912584 @default.
• W4381051334 cites W3048710994 @default.
• W4381051334 cites W3101803894 @default.
• W4381051334 cites W3114894706 @default.
• W4381051334 cites W3130075370 @default.
• W4381051334 cites W3156767904 @default.
• W4381051334 cites W3178548350 @default.
• W4381051334 cites W3184417164 @default.
• W4381051334 cites W3193578716 @default.
• W4381051334 cites W3200507062 @default.
• W4381051334 cites W4281975795 @default.
• W4381051334 cites W4292622311 @default.
• W4381051334 cites W4297348257 @default.
• W4381051334 doi "https://doi.org/10.1016/j.tice.2023.102145" @default.
• W4381051334 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37437331" @default.
• W4381051334 hasPublicationYear "2023" @default.
• W4381051334 type Work @default.
• W4381051334 citedByCount "0" @default.
• W4381051334 crossrefType "journal-article" @default.
• W4381051334 hasAuthorship W4381051334A5021293751 @default.
• W4381051334 hasAuthorship W4381051334A5023384331 @default.
• W4381051334 hasAuthorship W4381051334A5030719170 @default.
• W4381051334 hasAuthorship W4381051334A5062522582 @default.
• W4381051334 hasConcept C104317684 @default.
• W4381051334 hasConcept C126322002 @default.
• W4381051334 hasConcept C134018914 @default.
• W4381051334 hasConcept C170493617 @default.
• W4381051334 hasConcept C190283241 @default.
• W4381051334 hasConcept C196795494 @default.
• W4381051334 hasConcept C203014093 @default.
• W4381051334 hasConcept C2776151105 @default.
• W4381051334 hasConcept C2776415932 @default.
• W4381051334 hasConcept C2776914184 @default.
• W4381051334 hasConcept C2778923194 @default.
• W4381051334 hasConcept C2778938600 @default.
• W4381051334 hasConcept C2779422922 @default.
• W4381051334 hasConcept C2780073392 @default.
• W4381051334 hasConcept C2781443798 @default.
• W4381051334 hasConcept C55493867 @default.
• W4381051334 hasConcept C71924100 @default.
• W4381051334 hasConcept C86803240 @default.
• W4381051334 hasConcept C98274493 @default.
• W4381051334 hasConceptScore W4381051334C104317684 @default.
• W4381051334 hasConceptScore W4381051334C126322002 @default.
• W4381051334 hasConceptScore W4381051334C134018914 @default.
• W4381051334 hasConceptScore W4381051334C170493617 @default.
• W4381051334 hasConceptScore W4381051334C190283241 @default.
• W4381051334 hasConceptScore W4381051334C196795494 @default.
• W4381051334 hasConceptScore W4381051334C203014093 @default.
• W4381051334 hasConceptScore W4381051334C2776151105 @default.
• W4381051334 hasConceptScore W4381051334C2776415932 @default.
• W4381051334 hasConceptScore W4381051334C2776914184 @default.
• W4381051334 hasConceptScore W4381051334C2778923194 @default.
• W4381051334 hasConceptScore W4381051334C2778938600 @default.
• W4381051334 hasConceptScore W4381051334C2779422922 @default.
• W4381051334 hasConceptScore W4381051334C2780073392 @default.
• W4381051334 hasConceptScore W4381051334C2781443798 @default.
• W4381051334 hasConceptScore W4381051334C55493867 @default.
• W4381051334 hasConceptScore W4381051334C71924100 @default.
• W4381051334 hasConceptScore W4381051334C86803240 @default.
• W4381051334 hasConceptScore W4381051334C98274493 @default.
• W4381051334 hasFunder F4320317451 @default.
• W4381051334 hasLocation W43810513341 @default.
• W4381051334 hasLocation W43810513342 @default.
• W4381051334 hasOpenAccess W4381051334 @default.
• W4381051334 hasPrimaryLocation W43810513341 @default.
• W4381051334 hasRelatedWork W2004864370 @default.
• W4381051334 hasRelatedWork W2023082526 @default.
• W4381051334 hasRelatedWork W2347680429 @default.
• W4381051334 hasRelatedWork W2358254652 @default.
• W4381051334 hasRelatedWork W2358299559 @default.

• next