FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381158030> ?p ?o ?g. }

• W4381158030 endingPage "505" @default.
• W4381158030 startingPage "495" @default.
• W4381158030 abstract "ABSTRACTIntroduction Soluble interleukin-2 receptor (sIL-2 R), a valuable diagnostic biomarker for sarcoidosis, has been reported with variable results. Based on the literatures currently accessible, a systematic review and meta-analysis of the diagnostic performance of serum sIL-2 R for sarcoidosis were performed.Methods Relevant studies investigating sIL-2 R for sarcoidosis diagnosis in several databases were searched and data on sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR) were pooled by STATA 16.0 software. Overall test performance was assessed using summary receiver operating characteristic curves and the area under the curve (AUC). Potential publication bias was assessed by Deeks test.Results We included eleven studies involving 1,424 subjects, with 1,099 cases of sarcoidosis and 325 of non-sarcoidosis. The pooled parameters of sIL-2 R in diagnosing sarcoidosis were summarized as follows: sensitivity, 0.85 (95% CI: 0.72–0.93); specificity, 0.88 (95% CI: 0.72–0.96); PLR, 7.3 (95% CI: 2.7–20.1); NLR, 0.17 (95% CI:0.08–0.36); DOR, 44 (95% CI: 8–231); and the AUC, 0.93 (95% CI: 0.90–0.95). No publication bias was identified (P = 0.64).Conclusions Evidence suggests sIL-2 R performs well in diagnosing sarcoidosis. Nevertheless, results of sIL-2 R assay should be interpreted with other diagnostic examinations.KEYWORDS: Soluble interleukin-2 receptorsarcoidosisdiagnosisaccuracymeta-analysis Declaration of interestThe authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.Author contributionsD Qin and YC Shen conceived and designed the study. D Qin and LL Fan collected the data, performed the literature search and analyzed data. D Qin and YX Zhong wrote the manuscript. YC Shen and DY Cheng revise key parts of the manuscript. All authors have read and agreed to the published version of the manuscript.Reviewer disclosuresPeer reviewers on this manuscript have no relevant financial or other relationships to disclose.Supplementary materialSupplemental data for this article can be accessed online at https://doi.org/10.1080/17476348.2023.2225772.Additional informationFundingThis work was supported by grants from the 1•3•5 Project for Disciplines of Excellence, West China Hospital, Sichuan University (2019HXFH042) and Sichuan Key Research and Development Program (2020YFS0147). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript." @default.
• W4381158030 created "2023-06-20" @default.
• W4381158030 creator A5017014714 @default.
• W4381158030 creator A5021032631 @default.
• W4381158030 creator A5062933329 @default.
• W4381158030 creator A5066562599 @default.
• W4381158030 creator A5078159946 @default.
• W4381158030 date "2023-06-03" @default.
• W4381158030 modified "2023-09-27" @default.
• W4381158030 title "Diagnostic accuracy of interleukin-2 receptor in sarcoidosis: a systematic review and meta-analysis" @default.
• W4381158030 cites W1940134276 @default.
• W4381158030 cites W1995181043 @default.
• W4381158030 cites W2007833402 @default.
• W4381158030 cites W2009131553 @default.
• W4381158030 cites W2020488794 @default.
• W4381158030 cites W2025607940 @default.
• W4381158030 cites W2046014869 @default.
• W4381158030 cites W2046470313 @default.
• W4381158030 cites W2083346531 @default.
• W4381158030 cites W2086320143 @default.
• W4381158030 cites W2097435251 @default.
• W4381158030 cites W2104676202 @default.
• W4381158030 cites W2105758949 @default.
• W4381158030 cites W2107638293 @default.
• W4381158030 cites W2113009004 @default.
• W4381158030 cites W2114911311 @default.
• W4381158030 cites W2135636581 @default.
• W4381158030 cites W2139129657 @default.
• W4381158030 cites W2336621943 @default.
• W4381158030 cites W2416582336 @default.
• W4381158030 cites W2470932167 @default.
• W4381158030 cites W2593609323 @default.
• W4381158030 cites W2611560721 @default.
• W4381158030 cites W2767208211 @default.
• W4381158030 cites W2888926711 @default.
• W4381158030 cites W2909128569 @default.
• W4381158030 cites W2915848150 @default.
• W4381158030 cites W2980834605 @default.
• W4381158030 cites W2982381045 @default.
• W4381158030 cites W3014532306 @default.
• W4381158030 cites W3015330439 @default.
• W4381158030 cites W3044930638 @default.
• W4381158030 cites W3048772189 @default.
• W4381158030 cites W3085861571 @default.
• W4381158030 cites W3120012665 @default.
• W4381158030 cites W3120157664 @default.
• W4381158030 cites W3141256924 @default.
• W4381158030 cites W3150500703 @default.
• W4381158030 cites W3182419785 @default.
• W4381158030 cites W4211096509 @default.
• W4381158030 cites W4243621905 @default.
• W4381158030 cites W4281564829 @default.
• W4381158030 doi "https://doi.org/10.1080/17476348.2023.2225772" @default.
• W4381158030 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37334768" @default.
• W4381158030 hasPublicationYear "2023" @default.
• W4381158030 type Work @default.
• W4381158030 citedByCount "0" @default.
• W4381158030 crossrefType "journal-article" @default.
• W4381158030 hasAuthorship W4381158030A5017014714 @default.
• W4381158030 hasAuthorship W4381158030A5021032631 @default.
• W4381158030 hasAuthorship W4381158030A5062933329 @default.
• W4381158030 hasAuthorship W4381158030A5066562599 @default.
• W4381158030 hasAuthorship W4381158030A5078159946 @default.
• W4381158030 hasConcept C126322002 @default.
• W4381158030 hasConcept C144494922 @default.
• W4381158030 hasConcept C156957248 @default.
• W4381158030 hasConcept C157481446 @default.
• W4381158030 hasConcept C2780439572 @default.
• W4381158030 hasConcept C2781301800 @default.
• W4381158030 hasConcept C58471807 @default.
• W4381158030 hasConcept C71924100 @default.
• W4381158030 hasConcept C76318530 @default.
• W4381158030 hasConcept C90924648 @default.
• W4381158030 hasConcept C95190672 @default.
• W4381158030 hasConceptScore W4381158030C126322002 @default.
• W4381158030 hasConceptScore W4381158030C144494922 @default.
• W4381158030 hasConceptScore W4381158030C156957248 @default.
• W4381158030 hasConceptScore W4381158030C157481446 @default.
• W4381158030 hasConceptScore W4381158030C2780439572 @default.
• W4381158030 hasConceptScore W4381158030C2781301800 @default.
• W4381158030 hasConceptScore W4381158030C58471807 @default.
• W4381158030 hasConceptScore W4381158030C71924100 @default.
• W4381158030 hasConceptScore W4381158030C76318530 @default.
• W4381158030 hasConceptScore W4381158030C90924648 @default.
• W4381158030 hasConceptScore W4381158030C95190672 @default.
• W4381158030 hasFunder F4320337504 @default.
• W4381158030 hasIssue "6" @default.
• W4381158030 hasLocation W43811580301 @default.
• W4381158030 hasLocation W43811580302 @default.
• W4381158030 hasOpenAccess W4381158030 @default.
• W4381158030 hasPrimaryLocation W43811580301 @default.
• W4381158030 hasRelatedWork W1651000043 @default.
• W4381158030 hasRelatedWork W2010098735 @default.
• W4381158030 hasRelatedWork W2044638794 @default.
• W4381158030 hasRelatedWork W3089272739 @default.
• W4381158030 hasRelatedWork W4220920398 @default.
• W4381158030 hasRelatedWork W4285726763 @default.
• W4381158030 hasRelatedWork W4301401189 @default.

• next