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- W4381248378 abstract "A 2.4-kg male child of nonconsanguinity was born by difficult normal labor to a 24-year-old second-gravida mother. The mother was admitted with a history of leaking per vagina and abdominal pain for 2 days. All routine antenatal checkups were done. There was no history of any fever with rash, diabetes, hypertension, drug intake, decreased fetal movement, or any radiation exposure in the mother. The first child is healthy without any syndrome or any anomalies. There was a history of prolonged second-stage labor, and the delivery was difficult. The baby cried immediately after birth and was breastfed immediately. The baby was brought by relatives on day 2 of life with a history of skin defects and scalp ulcers. They noticed this swelling after 1 day. There was no history of any fever, lethargy, poor feeding, seizures, or any neurodeficit. On examination, the baby was active and conscious, and all vitals were stable. On scalp examination, a total of 3 different types of well-defined scalp defects of approximately 2.2 cm × 1.5 cm, 1.4 cm × 1.2 cm. and 0.75 cm × 0.5 cm were noticed. The margins were red-colored, well-circumscribed, and regular with no indentation and no bleeding from the site without any evidence of inflammation as shown in Figure 1. There was a localized loss of hair in the affected area and underlying bone was visible. No other skeletal defects were seen. The anterior fontanelle was normal in size and shape. The rest of the systemic examination was insignificant. A cranial ultrasonography was done, which was found to be normal. Seeing the type of lesions, dermatologist’s opinion was taken, and finally, we made the diagnosis of aplasia cutis congenita.Figure 1: Three well-circumscribed scalp defects of size approximately 2.2 cm × 1.5 cm, 1.4 cm × 1.2 cm, and 0.75 cm × 0.5 cm lesions with well-defined erythematous margins without any perilesional edema and absence of bleeding in the surrounding areaRelatives correlated these ulcers with the traumatic delivery process and presumed these marks to be instrument marks. We carefully observed the lesion and found that there were no injury marks surrounding the skin and no abrasion or ulceration over the scalp. We decided to give conservative treatment as there was no other localized lesion or any neurodeficit and the nature of disease was explained to relatives and they were counseled. After a 7-day course of treatment, the patient was absolutely alright with spontaneous ulcer healing. Aplasia cutis congenita is a very rare entity seen in newborn where mostly the dermis or epidermis or scalp and bones are involved. The overall incidence is 0.3 percent, but some mild cases go unreported because doctors are unfamiliar with the condition.[1] Newborns are generally born with skin defects, including well-described scalp ulcers, absence of skin at the vertex, and even calvarial skull defects. The scalp is the most common site, but the arms, trunk, and legs may also be involved. Sometimes patients may have only a transparent membrane over the lesion area, and the underlying organ can be seen clearly through the membrane. Chokoeva et al.[2] described aplasia cutis congenita in a 2-month-old baby who presented with an isolated scalp defect on the vertex of the head. The clinical presentation varies from patient to patient and depends on the severity and underlying defect. Cutis aplasia congenital over the scalp vertex, calvarial skull defect, localized well-defined skin defect, and spinal dysraphism is often seen in 80%–90% of patients.[3] The exact etiology is not clear and is supposed to be multifactorial. The possible reasons may be teratogenic effects of drugs, decreased blood supply to scalp tissues, genetic predisposition, trauma, and developmental abnormalities. One more variety is called cutis aplasia hair collar lesion type: where the defect is bigger and located in the midline, it is associated with a tuft of hair and adipose tissue at the base. The management and outcome depend upon the type, location of the lesion, and other associations. It is sometimes linked to meningomyelocele, midline defects, and spinal dysraphism. The complications may be meningitis, septicemia, hemorrhage, and sinus venous thrombosis.[4] Simple aplasia cutis congenita is a benign ulcer that heals in a few days with good wound care, and local antiseptic applications but may require systemic antibiotics to prevent infection. If there are no associated anomalies or other syndromic features, then parents should be reassured. If the lesions are in the midline, they warrant careful evaluation as the chances of complications are greater.[5] It carries good prognosis without any cosmetic or poor neurological outcome. TAKE HOME MESSAGE These entities closely resemble new ulcers and occasionally may cause misunderstanding for the treating physicians and family members who may correlate and interpret these lesions as trauma during labor. The pediatrician must be familiar with the entity to do an accurate examination and counsel the patient’s family appropriately, emphasizing the etiopathogenesis and prognosis. Such infants can be treated with the bare minimum of intervention by simple observation and sepsis prevention. Declaration of patient consent The authors clarify that they have obtained all appropriate consent from patients’ relatives. In the form, the relatives have given their consent for the image and other clinical information to be reported in the journal. They understand that their names and initials will not be published and due efforts will made to conceal their identity, but anonymity cannot be guaranteed. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest." @default.
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- W4381248378 date "2023-01-01" @default.
- W4381248378 modified "2023-09-26" @default.
- W4381248378 title "A Rare Case of Cutis Aplasia Congenita in a Newborn" @default.
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- W4381248378 doi "https://doi.org/10.4103/jdmimsu.jdmimsu_664_22" @default.
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