FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381252273> ?p ?o ?g. }

• W4381252273 endingPage "4104" @default.
• W4381252273 startingPage "4104" @default.
• W4381252273 abstract "Although the rate of infection after the reconstruction of a ruptured anterior cruciate ligament (ACL) is low, prophylactic incubation of the graft with vancomycin (Vanco-wrap or vancomycin soaking) is routinely performed. A cytotoxic effect of vancomycin is reported for several cell types, and the prophylactic treatment might prevent infection but harm the tissue and cells.A comprehensive study was performed to investigate the effect of vancomycin on tendon tissue and isolated tenocytes using cell viability, molecular and mechanical analysis.Rat tendons or isolated tenocytes were incubated in increasing concentrations of vancomycin (0-10 mg/mL) for different times, and cell viability, gene expression, histology and Young's modulus were analyzed.The clinically used concentration of vancomycin (5 mg/mL for 20 min) had no negative effect on cell viability in the tendons or the isolated tenocytes, while incubation with the toxic control significantly reduced cell viability. Increasing the concentration and prolonging the incubation time had no negative effect on the cells. The expression of Col1a1, Col3a1 and the tenocyte markers mohawk, scleraxis and tenomodulin was not affected by the various vancomycin concentrations. The structural integrity as measured through histological and mechanical testing was not compromised.The results proved the safe application of the Vanco-wrap on tendon tissue.IV." @default.
• W4381252273 created "2023-06-20" @default.
• W4381252273 creator A5000487908 @default.
• W4381252273 creator A5010812199 @default.
• W4381252273 creator A5011049345 @default.
• W4381252273 creator A5049423085 @default.
• W4381252273 creator A5069025368 @default.
• W4381252273 creator A5076383969 @default.
• W4381252273 date "2023-06-17" @default.
• W4381252273 modified "2023-09-29" @default.
• W4381252273 title "Wrap It! Preventive Antimicrobial Treatment Shows No Negative Effects on Tenocytes and Tendons—A Comprehensive Approach" @default.
• W4381252273 cites W1972431610 @default.
• W4381252273 cites W1983214667 @default.
• W4381252273 cites W1991974299 @default.
• W4381252273 cites W199341084 @default.
• W4381252273 cites W2013200703 @default.
• W4381252273 cites W2032073809 @default.
• W4381252273 cites W2056026648 @default.
• W4381252273 cites W2119584750 @default.
• W4381252273 cites W2142564221 @default.
• W4381252273 cites W2149195993 @default.
• W4381252273 cites W2156498074 @default.
• W4381252273 cites W2329641396 @default.
• W4381252273 cites W2397521526 @default.
• W4381252273 cites W2486863554 @default.
• W4381252273 cites W2604370284 @default.
• W4381252273 cites W2789398128 @default.
• W4381252273 cites W2807749865 @default.
• W4381252273 cites W2883240658 @default.
• W4381252273 cites W2910018458 @default.
• W4381252273 cites W2913881017 @default.
• W4381252273 cites W2916599346 @default.
• W4381252273 cites W2937814326 @default.
• W4381252273 cites W2963168786 @default.
• W4381252273 cites W3014394448 @default.
• W4381252273 cites W3023767747 @default.
• W4381252273 cites W3048422295 @default.
• W4381252273 cites W3084091632 @default.
• W4381252273 cites W3087485339 @default.
• W4381252273 cites W3097482974 @default.
• W4381252273 cites W3097722472 @default.
• W4381252273 cites W3120890592 @default.
• W4381252273 cites W3174801302 @default.
• W4381252273 cites W3190267728 @default.
• W4381252273 cites W3198527593 @default.
• W4381252273 cites W3207252223 @default.
• W4381252273 cites W4205118819 @default.
• W4381252273 cites W4210454569 @default.
• W4381252273 cites W4212918908 @default.
• W4381252273 cites W4213097063 @default.
• W4381252273 cites W4213443205 @default.
• W4381252273 cites W4226143174 @default.
• W4381252273 cites W4236822530 @default.
• W4381252273 cites W4238357148 @default.
• W4381252273 cites W4244563543 @default.
• W4381252273 cites W4309024271 @default.
• W4381252273 cites W4312054752 @default.
• W4381252273 cites W4362614197 @default.
• W4381252273 cites W4377690880 @default.
• W4381252273 doi "https://doi.org/10.3390/jcm12124104" @default.
• W4381252273 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37373797" @default.
• W4381252273 hasPublicationYear "2023" @default.
• W4381252273 type Work @default.
• W4381252273 citedByCount "0" @default.
• W4381252273 crossrefType "journal-article" @default.
• W4381252273 hasAuthorship W4381252273A5000487908 @default.
• W4381252273 hasAuthorship W4381252273A5010812199 @default.
• W4381252273 hasAuthorship W4381252273A5011049345 @default.
• W4381252273 hasAuthorship W4381252273A5049423085 @default.
• W4381252273 hasAuthorship W4381252273A5069025368 @default.
• W4381252273 hasAuthorship W4381252273A5076383969 @default.
• W4381252273 hasBestOaLocation W43812522731 @default.
• W4381252273 hasConcept C141071460 @default.
• W4381252273 hasConcept C1491633281 @default.
• W4381252273 hasConcept C25642318 @default.
• W4381252273 hasConcept C2778980435 @default.
• W4381252273 hasConcept C2779489039 @default.
• W4381252273 hasConcept C2780105995 @default.
• W4381252273 hasConcept C523546767 @default.
• W4381252273 hasConcept C53227056 @default.
• W4381252273 hasConcept C54355233 @default.
• W4381252273 hasConcept C55493867 @default.
• W4381252273 hasConcept C71924100 @default.
• W4381252273 hasConcept C86803240 @default.
• W4381252273 hasConceptScore W4381252273C141071460 @default.
• W4381252273 hasConceptScore W4381252273C1491633281 @default.
• W4381252273 hasConceptScore W4381252273C25642318 @default.
• W4381252273 hasConceptScore W4381252273C2778980435 @default.
• W4381252273 hasConceptScore W4381252273C2779489039 @default.
• W4381252273 hasConceptScore W4381252273C2780105995 @default.
• W4381252273 hasConceptScore W4381252273C523546767 @default.
• W4381252273 hasConceptScore W4381252273C53227056 @default.
• W4381252273 hasConceptScore W4381252273C54355233 @default.
• W4381252273 hasConceptScore W4381252273C55493867 @default.
• W4381252273 hasConceptScore W4381252273C71924100 @default.
• W4381252273 hasConceptScore W4381252273C86803240 @default.
• W4381252273 hasIssue "12" @default.
• W4381252273 hasLocation W43812522731 @default.

• next