FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381252497> ?p ?o ?g. }

• W4381252497 endingPage "101448" @default.
• W4381252497 startingPage "101448" @default.
• W4381252497 abstract "We investigate the roles of genetic predispositions, childhood SES and adult educational attainment in shaping trajectories for three important components of the overall health of older adults -- BMI, depressive symptoms and cognition. We use the Health & Retirement Study (HRS) and group-based trajectory modeling (GBTM) to identify subgroups of people who share the same underlying trajectories ages 51-94 years. After identifying common underlying health trajectories, we use fractional multinomial logit models to estimate associations of (1) polygenic scores for BMI, depression, ever-smoked, education, cognition and subjective wellbeing, (2) childhood SES and (3) educational attainment with the probabilities of trajectory group memberships. While genetic predispositions do play a part in predicting trajectory group memberships, our results highlight the long arm of socioeconomic factors. Educational attainment is the most robust predictor-it predicts increased probabilities of belonging to trajectories with BMI in the normal range, low depressive symptoms and very-high initial cognition. Childhood circumstances are manifested in trajectories to a lesser extent, with childhood SES predicting higher likelihood of being on the low depressive symptoms and very-high initial cognition trajectories. We also find suggestive evidence that associations of educational attainment on the probabilities of being on trajectories with BMI in the normal range, low depressive symptoms and very-high initial cognition vary with genetic predispositions. Our results suggest that policies to increase educational attainment may improve population health by increasing the likelihood of belonging to good aging trajectories." @default.
• W4381252497 created "2023-06-20" @default.
• W4381252497 creator A5014233573 @default.
• W4381252497 creator A5031652001 @default.
• W4381252497 creator A5043862366 @default.
• W4381252497 creator A5063181999 @default.
• W4381252497 creator A5075195476 @default.
• W4381252497 date "2023-06-01" @default.
• W4381252497 modified "2023-10-16" @default.
• W4381252497 title "Heterogenous trajectories in physical, mental and cognitive health among older Americans: Roles of genetics and life course contextual factors" @default.
• W4381252497 cites W1929683447 @default.
• W4381252497 cites W1964931457 @default.
• W4381252497 cites W1965011153 @default.
• W4381252497 cites W1985933989 @default.
• W4381252497 cites W1992903037 @default.
• W4381252497 cites W2020649988 @default.
• W4381252497 cites W2023036351 @default.
• W4381252497 cites W2038652719 @default.
• W4381252497 cites W2039153962 @default.
• W4381252497 cites W2040925948 @default.
• W4381252497 cites W2044594882 @default.
• W4381252497 cites W2062031031 @default.
• W4381252497 cites W2063408601 @default.
• W4381252497 cites W2065692954 @default.
• W4381252497 cites W2070001648 @default.
• W4381252497 cites W2071505844 @default.
• W4381252497 cites W2084491175 @default.
• W4381252497 cites W2085183720 @default.
• W4381252497 cites W2088803718 @default.
• W4381252497 cites W2094193647 @default.
• W4381252497 cites W2102970858 @default.
• W4381252497 cites W2110846909 @default.
• W4381252497 cites W2112658198 @default.
• W4381252497 cites W2136907554 @default.
• W4381252497 cites W2139846893 @default.
• W4381252497 cites W2141369642 @default.
• W4381252497 cites W2153190846 @default.
• W4381252497 cites W2254893897 @default.
• W4381252497 cites W2286293453 @default.
• W4381252497 cites W2336993262 @default.
• W4381252497 cites W2346626662 @default.
• W4381252497 cites W2346790561 @default.
• W4381252497 cites W2346990759 @default.
• W4381252497 cites W2592401173 @default.
• W4381252497 cites W2598022332 @default.
• W4381252497 cites W2620619966 @default.
• W4381252497 cites W2724375316 @default.
• W4381252497 cites W2761944943 @default.
• W4381252497 cites W2767859606 @default.
• W4381252497 cites W2772167081 @default.
• W4381252497 cites W2779292813 @default.
• W4381252497 cites W2802395378 @default.
• W4381252497 cites W2883573930 @default.
• W4381252497 cites W2883666524 @default.
• W4381252497 cites W2895625430 @default.
• W4381252497 cites W2912582321 @default.
• W4381252497 cites W2917754423 @default.
• W4381252497 cites W2919131444 @default.
• W4381252497 cites W2936461437 @default.
• W4381252497 cites W2953204040 @default.
• W4381252497 cites W2964945774 @default.
• W4381252497 cites W2972529548 @default.
• W4381252497 cites W2986804770 @default.
• W4381252497 cites W3000001784 @default.
• W4381252497 cites W3005276084 @default.
• W4381252497 cites W3036758454 @default.
• W4381252497 cites W3039499104 @default.
• W4381252497 cites W3162010007 @default.
• W4381252497 cites W3165183252 @default.
• W4381252497 cites W3167810400 @default.
• W4381252497 cites W4236917116 @default.
• W4381252497 cites W4245198606 @default.
• W4381252497 cites W4252307431 @default.
• W4381252497 cites W4321598953 @default.
• W4381252497 cites W4361772805 @default.
• W4381252497 doi "https://doi.org/10.1016/j.ssmph.2023.101448" @default.
• W4381252497 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37520306" @default.
• W4381252497 hasPublicationYear "2023" @default.
• W4381252497 type Work @default.
• W4381252497 citedByCount "0" @default.
• W4381252497 crossrefType "journal-article" @default.
• W4381252497 hasAuthorship W4381252497A5014233573 @default.
• W4381252497 hasAuthorship W4381252497A5031652001 @default.
• W4381252497 hasAuthorship W4381252497A5043862366 @default.
• W4381252497 hasAuthorship W4381252497A5063181999 @default.
• W4381252497 hasAuthorship W4381252497A5075195476 @default.
• W4381252497 hasBestOaLocation W43812524971 @default.
• W4381252497 hasConcept C117568660 @default.
• W4381252497 hasConcept C118552586 @default.
• W4381252497 hasConcept C119857082 @default.
• W4381252497 hasConcept C134362201 @default.
• W4381252497 hasConcept C138496976 @default.
• W4381252497 hasConcept C144024400 @default.
• W4381252497 hasConcept C147077947 @default.
• W4381252497 hasConcept C149923435 @default.
• W4381252497 hasConcept C15744967 @default.
• W4381252497 hasConcept C162324750 @default.
• W4381252497 hasConcept C1691868 @default.

• next