Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381279863> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4381279863 abstract "Abstract This study examined potential of the extracts obtained from the byproducts generated at commercial pecan nut shelling operations in cancer treatment. The subcritical water extracts obtained from two varieties, Native and Pawnee, were analyzed for their phenolic contents and compositions. Effects of the extracts on viability and IC50 of the human cell lines representing a broad range of cancer types, cervical, lung, skin, breast, colon and prostate cancers, were investigated. Although the effect of the temperature on the phenolic contents and compositions of the extracts was not statistically significant, the influence of the variety was extensive. The pecan shell extracts were not cytotoxic to the healthy cell line Vero in the concentration range examined. Some of the pecan shell extracts had greater efficay than Doxorubicin, a drug used in cancer chemotherapy, in reducing cancer cell viability. This study is novel and practical implications of the data generated in this study are noteworthy, because this is the first report on the beneficial effects of subcritical water extracts obtained from pecan shelling industry byproducts on a broad range of cancer cell lines. It is likely that the experimental data presented in this study will support and encourage future research on the biological pathways involved in the interactions of the cancer cells and the extracts. The findings of this study will facilitate research on downstream processing and purification of the crude extracts exhibiting high cancer cell cytotoxcity, potentially improving the final product efficacy and leading to commercial applications." @default.
- W4381279863 created "2023-06-21" @default.
- W4381279863 creator A5014294571 @default.
- W4381279863 creator A5048132140 @default.
- W4381279863 creator A5059642574 @default.
- W4381279863 date "2023-05-30" @default.
- W4381279863 modified "2023-09-27" @default.
- W4381279863 title "Cytotoxicity of subcritical water extracts obtained from byproducts generated at commercial pecan shelling operations on cancer cells" @default.
- W4381279863 cites W1576303827 @default.
- W4381279863 cites W1963481102 @default.
- W4381279863 cites W1969734406 @default.
- W4381279863 cites W1979317477 @default.
- W4381279863 cites W1985583887 @default.
- W4381279863 cites W1991300511 @default.
- W4381279863 cites W2052064928 @default.
- W4381279863 cites W2066641445 @default.
- W4381279863 cites W2160657822 @default.
- W4381279863 cites W2477222598 @default.
- W4381279863 cites W2743813625 @default.
- W4381279863 cites W2768048116 @default.
- W4381279863 cites W2946589123 @default.
- W4381279863 cites W3156276033 @default.
- W4381279863 cites W3191225109 @default.
- W4381279863 cites W4282012649 @default.
- W4381279863 cites W4295413797 @default.
- W4381279863 cites W4318253513 @default.
- W4381279863 cites W4318712187 @default.
- W4381279863 doi "https://doi.org/10.21203/rs.3.rs-2943734/v1" @default.
- W4381279863 hasPublicationYear "2023" @default.
- W4381279863 type Work @default.
- W4381279863 citedByCount "0" @default.
- W4381279863 crossrefType "posted-content" @default.
- W4381279863 hasAuthorship W4381279863A5014294571 @default.
- W4381279863 hasAuthorship W4381279863A5048132140 @default.
- W4381279863 hasAuthorship W4381279863A5059642574 @default.
- W4381279863 hasBestOaLocation W43812798631 @default.
- W4381279863 hasConcept C109316439 @default.
- W4381279863 hasConcept C121608353 @default.
- W4381279863 hasConcept C1491633281 @default.
- W4381279863 hasConcept C185592680 @default.
- W4381279863 hasConcept C202751555 @default.
- W4381279863 hasConcept C2780192828 @default.
- W4381279863 hasConcept C2994372470 @default.
- W4381279863 hasConcept C31903555 @default.
- W4381279863 hasConcept C53227056 @default.
- W4381279863 hasConcept C54355233 @default.
- W4381279863 hasConcept C55493867 @default.
- W4381279863 hasConcept C81885089 @default.
- W4381279863 hasConcept C86803240 @default.
- W4381279863 hasConcept C96232424 @default.
- W4381279863 hasConceptScore W4381279863C109316439 @default.
- W4381279863 hasConceptScore W4381279863C121608353 @default.
- W4381279863 hasConceptScore W4381279863C1491633281 @default.
- W4381279863 hasConceptScore W4381279863C185592680 @default.
- W4381279863 hasConceptScore W4381279863C202751555 @default.
- W4381279863 hasConceptScore W4381279863C2780192828 @default.
- W4381279863 hasConceptScore W4381279863C2994372470 @default.
- W4381279863 hasConceptScore W4381279863C31903555 @default.
- W4381279863 hasConceptScore W4381279863C53227056 @default.
- W4381279863 hasConceptScore W4381279863C54355233 @default.
- W4381279863 hasConceptScore W4381279863C55493867 @default.
- W4381279863 hasConceptScore W4381279863C81885089 @default.
- W4381279863 hasConceptScore W4381279863C86803240 @default.
- W4381279863 hasConceptScore W4381279863C96232424 @default.
- W4381279863 hasLocation W43812798631 @default.
- W4381279863 hasOpenAccess W4381279863 @default.
- W4381279863 hasPrimaryLocation W43812798631 @default.
- W4381279863 hasRelatedWork W1578197313 @default.
- W4381279863 hasRelatedWork W1972865454 @default.
- W4381279863 hasRelatedWork W1973169836 @default.
- W4381279863 hasRelatedWork W1991092689 @default.
- W4381279863 hasRelatedWork W2072873957 @default.
- W4381279863 hasRelatedWork W2094014322 @default.
- W4381279863 hasRelatedWork W2763585477 @default.
- W4381279863 hasRelatedWork W3094624880 @default.
- W4381279863 hasRelatedWork W4220678905 @default.
- W4381279863 hasRelatedWork W4309341410 @default.
- W4381279863 isParatext "false" @default.
- W4381279863 isRetracted "false" @default.
- W4381279863 workType "article" @default.