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- W4381330400 abstract "Background: Areca nut and betel quid (ANBQ) chewing is a widespread carcinogenic habit. The BENIT (ClinicalTrials.gov - NCT02942745) is the first known randomized trial designed for ANBQ chewers. Methods: We compared intensive behavioral treatment intervention condition (IC) with control condition (CC) in the BENIT and included a 5-stage early stopping rule. We report the primary analysis at stage 3. English literate adults in Guam and Saipan who self-identified as ANBQ chewers with tobacco were enrolled between August 2016 and August 2020. IC participants (n=88) received five in-person sessions over 22 days and a brochure containing quitting advice. CC participants (n=88) received only the brochure. Participants were assessed at baseline and day-22 follow-up. Self-reported chewing status at day-22 was determined by a composite of two survey items with disparate wording and response options for cross-verification. Results: Cessation rates were 38.6% (IC) and 9.1% (CC). Proportional hazards regression revealed a p=0.0058, which met the Stage 3 criteria for significance and an estimated reduction in ANBQ chewing for IC compared to the CC of 71% (95% CI: 41%-88%). Conclusion: Robust self-reported intervention effects at day-22 suggests that intensive cessation programs such as BENIT should be further developed and implemented on a larger scale." @default.
- W4381330400 created "2023-06-21" @default.
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- W4381330400 date "2023-06-20" @default.
- W4381330400 modified "2023-09-27" @default.
- W4381330400 title "The Betel Nut Intervention Trial (BENIT). A Randomized Clinical Trial for Areca Nut and Betel Quid Cessation: Primary Outcomes" @default.
- W4381330400 doi "https://doi.org/10.20944/preprints202306.1423.v1" @default.
- W4381330400 hasPublicationYear "2023" @default.
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